Inorganic Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 27, 2024
We
have
prepared
and
characterized
two
diradicaloid
systems
5a
5b
that
originated
from
the
oxidation
of
a
1,7-(4-(2,6-di-tert-butyl)phenol)-substituted
aza-BODIPY
core.
The
diradicaloids
were
by
large
array
experimental
computational
methods.
diamagnetic
closed-shell
state
was
postulated
as
ground
in
solution
solid-state
with
substantial
thermal
population
originating
both
open-shell
diradical
triplet
states
observed
at
room
temperature.
Transient
absorption
spectroscopy
indicates
fast
(<10
ps)
excited
deactivation
pathways
associated
target
compounds'
character
Variable-temperature
1H
NMR
spectra
indicate
solvent
dependency
5b.
could
be
stepwise
reduced
to
mixed-valence
radical-anion
dianion
upon
consequent
single-electron
reductions.
Similarly,
deprotonated
aza-BODIPYs
can
oxidized
form.
Both
dianionic
forms
exhibit
an
intense
NIR
region.
Density
functional
theory
(DFT)
time-dependent
DFT
calculations
used
explain
transformations
UV–Vis-NIR
all
compounds.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
34(36)
Published: March 29, 2024
Abstract
Fluorescence
imaging
in
the
second
near‐infrared
window
(NIR‐II,
1000–1700
nm)
has
aroused
immense
attention
for
biomedical
applications,
offering
exceptional
advantages
such
as
ultra‐low
photon
scattering
and
increased
tissue
penetration.
Among
NIR‐II‐emitted
organic
dyes,
Boron
dipyrromethene
(BODIPY),
emerged
a
noteworthy
candidate.
BODIPY,
distinguished
by
its
controllable
molecular
structure
optical
properties,
outstanding
fluorescence
quantum
yields,
high
molar
absorption
coefficients,
remarkable
chemical
stability,
undergone
comprehensive
investigation
extensive
exploration
within
realm
of
biological
theranostics.
This
work
aims
to
provide
summary
advancements
development
design
strategies
NIR‐II
BODIPY
fluorophores
tailored
advanced
phototheranostics.
Initially,
elucidates
several
representative
strategies,
concluding
electron‐programming
strategy,
extension
conjugated
backbone,
J‐aggregation
strategic
establishment
activatable
fluorophores,
which
enhance
skeletons.
Subsequently,
developments
fluorescent
BODIPY‐based
nanoplatforms
applications
are
intricately
elaborated.
In
conclusion,
this
outlines
future
efforts
directions
refining
meet
evolving
clinical
demands.
It
is
anticipated
that
contribution
may
feasible
reference
thereby
advancing
their
potential
practices.
Chemical Science,
Journal Year:
2024,
Volume and Issue:
15(20), P. 7408 - 7440
Published: Jan. 1, 2024
Recent
advances
in
synthesis
have
opened
the
way
to
a
variety
of
boron
helicenes.
We
highlight
main
achievements
these
chiral
compounds
and
discuss
their
photophysical
properties
potential
as
functional
materials.
Chemistry - An Asian Journal,
Journal Year:
2024,
Volume and Issue:
19(15)
Published: May 11, 2024
Organic
dyes
that
absorb
light
in
the
visible
to
near-infrared
region
have
garnered
significant
interest,
owing
their
extensive
utility
organic
photovoltaics
and
various
biomedical
applications.
Aza-boron-dipyrromethene
(Aza-BODIPY)
are
a
class
of
chromophores
with
impressive
photophysical
properties
such
as
tunable
absorption
from
towards
near
infrared
(NIR)
region,
high
molar
absorptivity,
fluorescence
quantum
yield.
In
this
review,
we
discuss
developments
aza-BODIPYs,
related
synthetic
routes,
Their
design
strategies,
modifications
chemical
structures,
mode/position
attachment,
impact
on
photo-physical
reviewed.
The
potential
applications
aza-BODIPY
derivatives
solar
cells,
photodynamic
therapy,
boron-neutron
capture
sensors,
photo-redox
catalysis,
photoacoustic
probes
optoelectronic
devices
explained.
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
13(28)
Published: July 28, 2024
Conventional
phototherapeutic
agents
are
typically
used
in
either
photodynamic
therapy
(PDT)
or
photothermal
(PTT).
However,
efficacy
is
often
hindered
by
hypoxia
and
elevated
levels
of
heat
shock
proteins
the
tumor
microenvironment
(TME).
To
address
these
limitations,
a
formylated,
near-infrared
(NIR)-absorbing
heavy-atom-free
Aza-BODIPY
dye
presented
that
exhibits
both
type-I
type-II
PDT
actions
with
high
yield
reactive
oxygen
species
(ROS)
manifests
efficient
conversion
precise
adjustments
to
conjugate
structure
electron
distribution,
leading
large
amount
ROS
production
even
under
severe
hypoxia.
improve
biosafety
water
solubility,
an
amphiphilic
triblock
copolymer
(Pluronic
F-127),
yielding
BDP-6@F127
nanoparticles
(NPs)
coated.
Furthermore,
inspired
fact
phototherapy
triggers
release
tumor-associated
antigens,
strategy
leverages
potential
immune
activation
combining
PDT/PTT
checkpoint
blockade
(ICB)
amplify
systemic
response
achieve
much-desired
abscopal
effect
developed.
In
conclusion,
this
study
presents
promising
molecular
design
integrates
multimodal
therapeutics
for
effective
approach
cancer
therapy.
