Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

Circulation, Journal Year: 2019, Volume and Issue: 139(10)

Published: Jan. 31, 2019

Language: Английский

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Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association

Circulation, Journal Year: 2020, Volume and Issue: 141(9)

Published: Jan. 29, 2020

The American Heart Association, in conjunction with the National Institutes of Health, annually reports on most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data a range major clinical circulatory disease conditions (including congenital rhythm disorders, subclinical atherosclerosis, coronary failure, valvular venous peripheral artery disease) associated outcomes quality care, procedures, economic costs).The through its Statistics Committee, continuously monitors evaluates sources stroke United States provide current information available annual Update. 2020 is product full year's worth effort by dedicated volunteer clinicians scientists, committed government professionals, Association staff members. This edition includes monitoring benefits population, metrics assess monitor healthy diets, an enhanced focus social determinants health, global burden further evidence-based approaches changing behaviors, implementation strategies, implications Association's Impact Goals.Each 26 chapters focuses different topic statistics.The represents critical resource for lay public, policy makers, media clinicians, healthcare administrators, researchers, advocates, others seeking best these conditions.

Language: Английский

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Heart Disease and Stroke Statistics—2021 Update

Circulation, Journal Year: 2021, Volume and Issue: 143(8)

Published: Jan. 27, 2021

The American Heart Association, in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data on a range major clinical circulatory disease conditions (including congenital rhythm disorders, subclinical atherosclerosis, coronary failure, valvular venous peripheral artery disease) associated outcomes quality care, procedures, economic costs).The through its Statistics Committee, continuously monitors evaluates sources stroke United States provide current information available annual Update. 2021 is product full year's worth effort by dedicated volunteer clinicians scientists, committed government professionals, Association staff members. This edition includes monitoring benefits population, an enhanced focus social determinants health, adverse pregnancy outcomes, vascular contributions brain global burden further evidence-based approaches changing disease.Each 27 chapters focuses different topic statistics.The represents critical resource for lay public, policy makers, media clinicians, care administrators, researchers, advocates, others seeking best these conditions.

Language: Английский

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Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

Circulation, Journal Year: 2022, Volume and Issue: 145(8)

Published: Jan. 26, 2022

The American Heart Association, in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data on a range major clinical circulatory disease conditions (including congenital rhythm disorders, subclinical atherosclerosis, coronary failure, valvular venous peripheral artery disease) associated outcomes quality care, procedures, economic costs).

Language: Английский

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Molecular mechanisms and physiological importance of circadian rhythms

Nature Reviews Molecular Cell Biology, Journal Year: 2019, Volume and Issue: 21(2), P. 67 - 84

Published: Nov. 25, 2019

Language: Английский

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Depression in sleep disturbance: A review on a bidirectional relationship, mechanisms and treatment

Journal of Cellular and Molecular Medicine, Journal Year: 2019, Volume and Issue: 23(4), P. 2324 - 2332

Published: Feb. 7, 2019

Abstract Sleep disturbance is the most prominent symptom in depressive patients and was formerly regarded as a main secondary manifestation of depression. However, many longitudinal studies have identified insomnia an independent risk factor for development emerging or recurrent depression among young, middle‐aged older adults. This bidirectional association between sleep has created new perspective that problems are no longer epiphenomenon but predictive prodromal symptom. In this review, we highlight treatment before, during after depression, which probably plays important role improving outcomes preventing recurrence clinical practice, pharmacological therapies, including hypnotics antidepressants, non‐pharmacological therapies typically applied. A better understanding pathophysiological mechanisms can help psychiatrists manage comorbidity.

Language: Английский

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Rhythms of life: circadian disruption and brain disorders across the lifespan

Nature reviews. Neuroscience, Journal Year: 2018, Volume and Issue: 20(1), P. 49 - 65

Published: Nov. 20, 2018

Language: Английский

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Crosstalk between metabolism and circadian clocks

Nature Reviews Molecular Cell Biology, Journal Year: 2019, Volume and Issue: 20(4), P. 227 - 241

Published: Jan. 11, 2019

Language: Английский

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Genomics of circadian rhythms in health and disease

Genome Medicine, Journal Year: 2019, Volume and Issue: 11(1)

Published: Dec. 1, 2019

Abstract Circadian clocks are endogenous oscillators that control 24-h physiological and behavioral processes. The central circadian clock exerts over myriad aspects of mammalian physiology, including the regulation sleep, metabolism, immune system. Here, we review advances in understanding genetic sleep through system, as well impact dysregulated gene expression on metabolic function. We also recent studies have begun to unravel clock’s role controlling cardiovascular nervous systems, gut microbiota, cancer, aging. Such these systems relies, part, transcriptional regulation, with evidence for genome-wide chromosome organization. These novel insights into genomic human physiology provide opportunities discovery improved treatment strategies new biological underpinnings disease.

Language: Английский

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Circadian Mechanisms in Medicine

New England Journal of Medicine, Journal Year: 2021, Volume and Issue: 384(6), P. 550 - 561

Published: Feb. 10, 2021

Molecular insights into diurnal variations in human physiology and behavior are extending our understanding of a wide range disease processes. Chronobiology is also providing testable hypotheses regarding the timing treatments.

Language: Английский

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