Gastrointestinal Disorders,
Journal Year:
2024,
Volume and Issue:
6(1), P. 164 - 179
Published: Feb. 8, 2024
Colorectal
cancer
(CRC)
is
a
disease
characterised
by
the
development
of
malignant
tumours
in
colon
or
rectum;
it
considered
most
common
women,
and
up
to
50%
cases
can
be
prevented
with
healthy
lifestyle.
Nutritional
habits
are
related
its
appearance,
current
trend
an
increased
consumption
ultra-processed
foods
(UPFs)
has
led
surge
incidence
CRC
recent
years.
This
systematic
review
aims
evaluate,
based
on
scientific
evidence,
role
UPF
CRC.
The
PubMed,
Scopus,
CINAHL,
Web
Science
databases
were
reviewed,
total
24
articles
selected
according
inclusion
exclusion
criteria
this
(studies
from
past
5
years
observational
studies
English).
conclusions
study
point
association
between
UPF-based
diets
appearance
CRC,
which
promoted
harmful
effects
high
levels
sugar,
fat,
red
meat,
additives.
These
dietary
habits,
coupled
sedentary
lifestyle
obesity,
further
increase
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(17), P. 3735 - 3735
Published: Aug. 25, 2023
Research
has
shown
that
high
amounts
of
dietary
phosphorus
are
twice
the
amount
U.S.
reference
intake
700
mg
for
adults
associated
with
all-cause
mortality,
phosphate
toxicity,
and
tumorigenesis.
The
present
nested
case-control
study
measured
relative
risk
self-reported
breast
cancer
over
10
annual
visits
in
a
cohort
middle-aged
women
from
Study
Women's
Health
Across
Nation.
Analyzing
data
food
frequency
questionnaires,
highest
level
daily
intake,
>1800
phosphorus,
was
approximately
equivalent
to
levels
menus
promoted
by
United
States
Department
Agriculture.
After
adjusting
participants'
energy
this
2.3-fold
increased
incidence
compared
800
1000
mg,
which
is
based
on
recommendations
National
Kidney
Foundation,
(RR:
2.30,
95%
CI:
0.94-5.61,
p
=
0.07).
Despite
lack
statistical
significance,
likely
due
small
sample
size
cohort,
study's
clinically
significant
effect
size,
dose-response,
temporality,
specificity,
biological
plausibility,
consistency,
coherence,
analogy
other
research
findings
meet
criteria
inferred
causality
observational
studies,
warranting
further
investigations.
Furthermore,
these
suggest
low-phosphate
diet
should
be
tested
patients
cancer.
Frontiers in Immunology,
Journal Year:
2024,
Volume and Issue:
15
Published: March 11, 2024
Objective
To
explore
the
influence
of
serum
metabolites
on
risk
psoriasis.
Methods
In
initial
stage,
we
applied
Mendelian
randomization
to
evaluate
association
between
1,400
and
Causal
effects
were
primarily
assessed
through
Inverse-Variance
Weighted
method
Wald
Ratio’s
odds
ratios,
95%
confidence
intervals.
False
Discovery
Rate
was
used
for
multiple
comparison
corrections.
Sensitivity
analyses
conducted
using
Cochran’s
Q
Test,
MR-PRESSO.
MR-Steiger
Test
employed
check
reverse
causality.
validation
sought
other
sources
psoriasis
GWAS
data
verify
results
meta-analysis
combine
effect
sizes
obtain
robust
causal
relationships.
addition,
also
metabolic
pathway
enrichment
analysis
known
that
have
a
relationship
with
in
both
stages.
Results
identified
112
causally
associated
psoriasis,
including
32
metabolite
ratios
80
(69
11
unknown).
24
(16
known,
1
unknown,
7
ratios)
confirmed
onset.
Meta-analysis
showed
overall
combined
consistent
main
direction
Of
16
metabolites,
most
attributed
lipid
metabolism,
5
as
factors
8
protective
Peptidic
Gamma-glutamylvaline
levels
had
negative
while
exogenous
Catechol
sulfate
amino
acid
3-methylglutaconate
positive
disease
The
two
stages
are
mainly
enriched
following
pathways:
Glutathione
Alpha
Linolenic
Acid
Linoleic
Metabolism,
Biosynthesis
unsaturated
fatty
acids,
Arachidonic
Glycerophospholipid
metabolism.
Conclusion
Circulating
may
potential
risk,
targeting
specific
benefit
diagnosis,
assessment,
treatment.
Deleted Journal,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 19, 2024
Abstract
Incidence
of
non-communicable
diseases
(NCDs)
such
as
diabetes
and
obesity
is
on
the
rise
worldwide.
Rising
consumption
ultra-processed
food
(UPF)
products
or
those
high
in
fats,
sugars
salt
also
called
junk
foods
contributes
to
this
grave
situation.
Increasing
UPFs
associated
with
obesity,
type-2
diabetes,
cardiovascular
disease,
cancers,
cerebral
vascular
disease
all-cause
mortality.
Aggressive
pervasive
marketing
targeting
children
adolescents
leads
development
preference
for
foods,
turns
diets
be
unhealthy.
India
made
progress
2017
document
recommend
through
national
multisectoral
plan
action
prevent
control
NCDs
using
legal
measures
have
front-of-the-pack
labels
ban
advertisements.
However,
it
remains
implemented.
This
review
article
delves
into
scientific
evidence
why
there
need
prioritise
regulating
fat,
sugar
(HFSS)
India,
while
mass
awareness
citizens
risks
how
read
pre-packaged
foods.
Nutrition Reviews,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 31, 2025
Abstract
Context
Relationships
between
ultraprocessed
food
(UPF)
intakes
and
health
have
been
well
described
in
adults,
but
evidence
of
these
relationships
older
adults
is
rather
limited.
Demographic
shifts
aging
emphasize
the
importance
understanding
role
diet
maintaining
during
later
life.
Objective
The
aim
this
systematic
review
was
to
identify
outcomes
associated
with
UPF
consumption
those
aged
≥60
years.
Data
Sources
Medline,
Web
Science,
Scopus,
Embase
databases
were
searched
from
inception
until
June
2023,
using
search
terms
representing
any
outcome.
Observational
studies
restricted
individuals
years
Nova
classification
included.
Articles
screened
independently
by
2
researchers
PECOS
inclusion
criteria.
Extraction
Two-thirds
present
prospective
cohort
(n
=
4)
rest
cross-sectional
2).
number
participants
ranged
652
2713
across
6
studies.
mean
age
67
73
Analysis
In
studies,
highest
incident
frailty,
dyslipidemia,
renal
function
decline,
abdominal
obesity.
For
intake
negative
similar
young
middle-aged
cohorts,
addition
nutritional
frailty
worse
cognitive
performance.
Conclusions
Currently,
limited
how
high
could
be
for
influences
ability
inform
policy
practice
recommendations.
More
research
required
owing
very
specifically
adults.
Systematic
Review
Registration
PROSPERO
registration
no.
CRD42023442783.
Revista Brasileira de Cancerologia,
Journal Year:
2025,
Volume and Issue:
71(1)
Published: Feb. 3, 2025
Introdução:
O
consumo
de
alimentos
ultraprocessados
tem
aumentado
na
população
brasileira
nos
últimos
anos
e
está
associado
ao
desenvolvimento
agravamento
doenças
crônicas
como
o
câncer.
Objetivo:
Avaliar
por
mulheres
brasileiras
sobreviventes
dos
cânceres
mama,
ovário
colo
do
útero.
Método:
Estudo
transversal
com
informações
secundárias
da
Pesquisa
Nacional
Saúde
(2019),
um
inquérito
saúde
em
geral,
que
investigou
aspectos
sociodemográficos,
clínicos
alimentares,
onde
foram
coletadas
adultas
diagnósticos
autorreferidos
câncer
foi
avaliado
pelo
escore
NOVA,
baseado
frequência
tipos
ultraprocessados.
A
associação
entre
diagnóstico
explorada
usando
modelos
regressão
Poisson
variação
robusta,
software
Stata/MP
17.0.
Resultados:
prevalência
cinco
ou
mais
7,8%
as
histórico
câncer,
sendo
alta
menos
40
anos.
variou
conforme
índice
massa
corporal
tipo
maiores
prevalências
obesidade
útero
(RP=6,37;
IC95%:1,46;27,68).
Conclusão:
Pacientes
consomem
quantidade
expressiva,
Food Science and Technology International,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 18, 2025
Fermented
foods
are
a
good
option
due
to
the
beneficial
compounds
generated
in
fermentation
process
and
low
pH
that
allows
conservation
without
additives.
The
objective
of
study
was
produce
include
Tommy
mango
peel
flour
production
kombucha
evaluate
its
effects
on
physicochemical
sensory
properties,
antioxidant
capacity,
microbiological
profile.
developed
with
green
tea
addition
(10%
20%).
kombuchas
were
evaluated
first
(aerobic)
at
end
second
(anaerobic),
granulometry
colorimetry
profile
evaluated.
Microbiome
analysis
performed
by
16S
DNA
extraction.
For
analysis,
an
affective
test
for
global
evaluation,
flavor,
texture,
oral
perception.
results
showed
total
phenolic
content
4.86
mg
EAG/mL
F1,
8.79
F2
10%
flour,
8.83
±
0.54
20%
evidencing
significant
increase
flour.
In
addition,
activity
also
higher
fermentation.
values
obtained
F1
=
15.27
µmol
TE/mL;
FCMT
18.80
26.76
TE/mL.
These
findings
indicate
capacity
increases
significantly
during
fermentation,
directly
correlating
amount
added.
most
abundant
bacterial
genera
Liquorilactobacillus
nagelii
(72%),
Acetobacter
(13%),
Komagataeibacter
(12%)
fungi
(90%)
Brettanomyces/Dekkera
bruxellensis.
beverage
different
levels
acceptance
among
consumers
non-consumers
only
terms
proving
be
alternative
food
industry
applying
byproduct
drinks.
Current Oncology Reports,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 27, 2025
Abstract
Purposeof
Review
Ultra-processed
foods
(UPFs)
are
becoming
more
and
important
in
daily
diets
around
the
world;
some
cases,
they
can
account
for
as
much
60%
of
energy
intake.
Epidemiological
evidence
suggests
that
this
shift
toward
high
levels
food
processing
may
be
partially
responsible
global
obesity
epidemic
rise
prevalence
chronic
diseases.
Recent
Findings
Few
prospective
studies
have
examined
relationship
between
UPF
consumption
cancer
outcomes.
According
to
currently
available
information,
UPFs
increase
risk
due
their
obesogenic
properties
exposure
substances
cause
cancer,
such
certain
additives
pollution
from
product
processing.
The
complex
involves
factors
immune
dysregulation,
altered
adipokine
sex
hormone
levels,
abnormal
fatty
acid
metabolism,
extracellular
matrix
remodeling,
inflammation.
Addressing
associated
with
could
involve
a
multifaceted
approach,
including
consumer
behavior
modification
programs
robust
public
health
regulations
aimed
at
enhancing
environments.
Improved
knowledge
potential
dual
negative
impacts
on
environment
is
one
priority
areas
we
identify
future
research
policy
implications.
Various
approaches
used
prevent
cancers
consumption,
change
stricter
needed
improve
environment.
Summary
This
review
examines
first
time
role
obesity,
exploring
underlying
biological
mechanisms
identifying
key
action,
environmental
impact
UPFs.
