Rye Flour and Rye Bran: New Perspectives for Use DOI Open Access
Dariusz Dziki

Processes, Journal Year: 2022, Volume and Issue: 10(2), P. 293 - 293

Published: Feb. 1, 2022

Rye (Secale cereale L.) is abundantly cultivated in countries like Europe and North America, particularly regions where soil climate conditions are unfavorable for the growth of other cereals. Among all cereals generally consumed by human beings, rye grains characterized presence highest content fiber. They also a rich source many phytochemical compounds, which mainly distributed outer parts grain. This review focuses on current knowledge regarding characteristics bran wholemeal flour, as well their applications production both food nonfood products. Previous studies have shown that physicochemical properties ground products determined type milling technique used to grind grains. In addition, essential biologically active compounds found were isolated characterized. Subsequently, possibility incorporating bran, extracted from into different industrial discussed.

Language: Английский

Alzheimer’s disease and its treatment by different approaches: A review DOI

Sukriti Srivastava,

Razi Ahmad, Sunil Kumar Khare

et al.

European Journal of Medicinal Chemistry, Journal Year: 2021, Volume and Issue: 216, P. 113320 - 113320

Published: Feb. 23, 2021

Language: Английский

Citations

340

Microbial Nano-Factories: Synthesis and Biomedical Applications DOI Creative Commons

Shubhrima Ghosh,

Razi Ahmad, Md. Zeyaullah

et al.

Frontiers in Chemistry, Journal Year: 2021, Volume and Issue: 9

Published: April 16, 2021

In the recent times, nanomaterials have emerged in field of biology, medicine, electronics, and agriculture due to their immense applications. Owing nanoscale sizes, they present large surface/volume ratio, characteristic structures, similar dimensions biomolecules resulting unique properties for biomedical The chemical physical methods synthesize nanoparticles own limitations which can be overcome using biological synthesis. Moreover, through biogenic synthesis route, usage microorganisms has offered a reliable, sustainable, safe, environmental friendly technique nanosynthesis. Bacterial, algal, fungal, yeast cells are known transport metals from environment convert them elemental nanoparticle forms either accumulated or secreted. Additionally, robust nanocarriers also been developed viruses. order prevent aggregation promote stabilization nanoparticles, capping agents often secreted during biosynthesis. Microbial find applications rapid diagnostics, imaging, biopharmaceuticals, drug delivery systems, antimicrobials, biomaterials tissue regeneration as well biosensors. major challenges therapeutic microbial include biocompatibility, bioavailability, stability, degradation gastro-intestinal tract, immune response. Thus, current review article is focused on microbe-mediated various different strains explored such along with future

Language: Английский

Citations

185

Biosynthesis of selenium nanoparticles using plant extracts DOI Creative Commons
Krystyna Pyrzyńska, Aleksandra Sentkowska

Journal of nanostructure in chemistry, Journal Year: 2021, Volume and Issue: 12(4), P. 467 - 480

Published: July 28, 2021

Abstract Selenium nanoparticles (SeNPs) have the potential to be used for various applications. Therefore, they attracted more attention in recent years and several synthesis methods been exploited. Green using plant extracts has gained popularity because it requires non-toxic solvents moderate temperatures. Furthermore, is environmentally friendly uses a reducing agent that easily accessible biodegradable. In this review, we present reports concerning capability of different materials biosynthesis selenium nanoparticles. The conditions (temperature, time, precursor, extract concentration) are discussed combination with characteristics obtained product (composition, size, shape, stability). application synthesized was briefly presented. Graphic abstract

Language: Английский

Citations

141

Cervical cancer: Novel treatment strategies offer renewed optimism DOI

Gangotri yadav,

Ganga Srinivasan,

Ashish Jain

et al.

Pathology - Research and Practice, Journal Year: 2024, Volume and Issue: 254, P. 155136 - 155136

Published: Jan. 15, 2024

Language: Английский

Citations

18

Advances in gene therapy approaches targeting neuro-inflammation in neurodegenerative diseases DOI
Kuldeep Singh, Pranshul Sethi, Samaresh Datta

et al.

Ageing Research Reviews, Journal Year: 2024, Volume and Issue: 98, P. 102321 - 102321

Published: May 8, 2024

Language: Английский

Citations

17

Effectiveness and mechanisms of essential oils for biofilm control on food-contact surfaces: An updated review DOI
Chiara Rossi, Clemencia Chaves‐López, Annalisa Serio

et al.

Critical Reviews in Food Science and Nutrition, Journal Year: 2020, Volume and Issue: 62(8), P. 2172 - 2191

Published: Nov. 30, 2020

Microbial biofilms represent a constant source of contamination in the food industry, being also real threat for human health. In fact, most biofilm-producing bacteria are becoming resistant to sanitizers, thus arousing interest natural alternatives prevent biofilm formation on foods and food-contact surfaces. particular, studies control by essential oils (EOs) application increasing, EOs characterized unique mixtures compounds able impair mechanisms development. This review reports anti-biofilm properties bacterial (inhibition, removal prevention dispersion) The relationship between effect composition, concentration, involved bacteria, surfaces is discussed, possible sites action elucidated. findings prove high controlling capability through regulation genes proteins implicated motility, Quorum Sensing exopolysaccharides (EPS) matrix. Moreover, incorporation nanosized delivery systems, formulation blends combination with other strategies can increase their activity. provides an overview current knowledge effectiveness surfaces, providing valuable information improving use as sanitizers industries.

Language: Английский

Citations

96

Chitosan-Coating Effect on the Characteristics of Liposomes: A Focus on Bioactive Compounds and Essential Oils: A Review DOI Open Access

Carine Sebaaly,

Adriana Trifan, Elwira Sieniawska

et al.

Processes, Journal Year: 2021, Volume and Issue: 9(3), P. 445 - 445

Published: March 1, 2021

In recent years, liposomes have gained increasing attention for their potential applications as drug delivery systems in the pharmaceutic, cosmetic and food industries. However, they a tendency to aggregate are sensitive degradation caused by several factors, which may limit effectiveness. A promising approach improve liposomal stability is modify surfaces forming polymeric layers. Among natural polymers, chitosan has received great interest due its biocompatibility biodegradability. This review discussed characteristics of this combined system, called chitosomes, comparison those conventional liposomes. The coating with or derivatives improved liposome stability, provided sustained release increased penetration across mucus mechanisms behind these results highlighted paper. Alternative assembly polyelectrolytes using alginate, sodium hyaluronate, pectin could further characteristics. Chitosomal encapsulation also ensure targeted boost antimicrobial efficacy essential oils (EOs). Moreover, chitosomes be an efficient tool overcome major drawbacks related chemical properties EOs (low water solubility, sensitivity oxygen, light, heat, humidity) poor bioavailability. Overall, considered strategy enlarge use

Language: Английский

Citations

68

Molecular Pathogenesis of Colorectal Cancer with an Emphasis on Recent Advances in Biomarkers, as Well as Nanotechnology-Based Diagnostic and Therapeutic Approaches DOI Creative Commons

Fakhria A. Al-Joufi,

Aseem Setia, Mounir M. Salem‐Bekhit

et al.

Nanomaterials, Journal Year: 2022, Volume and Issue: 12(1), P. 169 - 169

Published: Jan. 4, 2022

Colorectal cancer (CRC) is a serious disease that affects millions of people throughout the world, despite considerable advances in therapy. The formation colorectal adenomas and invasive adenocarcinomas consequence succession genetic epigenetic changes normal colonic epithelium. Genetic processes associated with onset, development, metastasis sporadic CRC have been studied depth, resulting identifying biomarkers might be used to predict behaviour prognosis beyond staging influence therapeutic options. A novel biomarker, or group biomarkers, must discovered order build an accurate clinically useful test may as alternative conventional methods for early detection identify prospective new intervention targets. To minimise mortality burden cancer, screening higher accuracy nano-based diagnostic precision are needed. Cytotoxic medication has negative side effects restricted by resistance. One most promising treatment techniques use carrier system delivery mechanism. deliver cytotoxic medicines, targeted nanoparticles take advantage differently expressed molecules on surface cells. different compounds ligands interact cells, enabling efficient antitumor medicines. Formulations based aid diagnosis help overcome limitations traditional treatments, including low water solubility, nonspecific biodistribution, bioavailability. This article addresses about molecular pathogenesis highlights biomarkers. It also provides conceptual knowledge nanotechnology-based approaches malignant cancer.

Language: Английский

Citations

67

COVID-19 and SARS-CoV-2 Variants: Current Challenges and Health Concern DOI Creative Commons
Md. Zeyaullah, Abdullah M. AlShahrani, Khursheed Muzammil

et al.

Frontiers in Genetics, Journal Year: 2021, Volume and Issue: 12

Published: June 15, 2021

The ongoing coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China, was triggered and unfolded quickly throughout the globe by severe acute respiratory syndrome 2 (SARS-CoV-2). new virus, transmitted primarily through inhalation or contact with infected droplets, seems very contagious pathogenic, an incubation period varying from to 14 days. epidemic is public health problem that challenges present global system. A worldwide social economic stress has been observed. transitional source of origin its transport humans unknown, but speedy human transportation accepted extensively. typical clinical symptoms COVID-19 are almost like colds. With case fatality rates 3 percent, a small number patients may experience serious problems even die. To date, there limited antiviral agents vaccines for treatment COVID-19. occurrence pathogenicity infection outlined comparatively analyzed, given outbreak’s urgency. recent developments diagnostics, treatment, marketed vaccine discussed deal this viral outbreak. Now scientist concerned about appearance several variants over efficacy against these variants. There need consistent monitoring virus epidemiology surveillance variant related severity.

Language: Английский

Citations

64

Innovative Delivery Systems Loaded with Plant Bioactive Ingredients: Formulation Approaches and Applications DOI Creative Commons
Anastasia Kyriakoudi, Eleni Spanidi, Ioannis Mourtzinos

et al.

Plants, Journal Year: 2021, Volume and Issue: 10(6), P. 1238 - 1238

Published: June 18, 2021

Plants constitute a rich source of diverse classes valuable phytochemicals (e.g., phenolic acids, flavonoids, carotenoids, alkaloids) with proven biological activity antioxidant, anti-inflammatory, antimicrobial, etc.). However, factors such as low stability, poor solubility and bioavailability limit their food, cosmetics pharmaceutical applications. In this regard, wide range delivery systems have been developed to increase the stability plant-derived bioactive compounds upon processing, storage or under gastrointestinal digestion conditions, enhance solubility, mask undesirable flavors well efficiently deliver them target tissues where they can exert promote human health. present review, latest advances regarding design innovative for pure plant compounds, extracts essential oils, in order overcome above-mentioned challenges, are presented. Moreover, broad spectrum applications along future trends critically discussed.

Language: Английский

Citations

61