A practical guide for researchers and reviewers using the ABCD Study and other large longitudinal datasets

Developmental Cognitive Neuroscience, Journal Year: 2022, Volume and Issue: 55, P. 101115 - 101115

Published: May 20, 2022

As the largest longitudinal study of adolescent brain development and behavior to date, Adolescent Brain Cognitive Development (ABCD) Study® has provided immense opportunities for researchers across disciplines since its first data release in 2018. The size scope also present a number hurdles, which range from becoming familiar with design structure employing rigorous reproducible analyses. current paper is intended as guide reviewers working ABCD data, highlighting features (and strengths limitations therein) well relevant analytical methodological considerations. Additionally, we explore justice, equity, diversity, inclusion efforts they pertain Study other large-scale datasets. In doing so, hope increase both accessibility transparency within field developmental cognitive neuroscience.

Language: Английский

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Association of Social Determinants of Health and Vaccinations With Child Mental Health During the COVID-19 Pandemic in the US

JAMA Psychiatry, Journal Year: 2022, Volume and Issue: 79(6), P. 610 - 610

Published: April 27, 2022

Importance

The COVID-19 pandemic disproportionately affected mental health in socioeconomically disadvantaged children the US. However, little is known about relationship of preexisting and time-varying social determinants (SDoH) at individual structural levels, vaccination eligibility/rates, racial ethnic differences to trajectories child during pandemic.

Objective

To estimate association multilevel SDoH eligibility/rates.

Design, Setting, Participants

This prospective longitudinal cohort study, conducted from May 16, 2020, March 2, 2021, integrated structural-level, pandemic-related data with Adolescent Brain Cognitive Development (ABCD) (release 4.0). ABCD study recruited 11 878 (baseline) 6 rapid response surveys across 21 US sites (in 17 states) 2021.

Exposures

Preexisting (eg, household income) (area deprivation) food insecurity, unemployment) distancing, eligibility/rates) SDoH.

Main Outcomes Measures

Perceived Stress Scale, National Institutes Health–Toolbox emotion measures, COVID-19–related worry.

Results

sample included 8493 (mean [SD] age, 9.93 [0.63] years; 5011 girls [47.89%]; 245 Asian [2.34%], 1213 Black [11.59%], 2029 Hispanic [19.39%], 5851 White [55.93%], 1124 other/multiracial ethnicity [10.74%]). Trajectories stress, sadness, worry decreased after adult rollout. Compared younger children, boys, or those living married parents, who reported greater perceived stress older aged 12 15 years (β = 0.26; 95% CI, 0.12-0.41;P < .001); 0.75; 0.61-0.89;P 0.24; 0.01-0.47;P .04); separated parents 0.50; 0.03-0.96;P experiencing disrupted medical care access 0.19; 0.01-0.36;P economically deprived neighborhoods 0.28; 0.05-0.51;P .02); areas more full-time working-class adults were unable distance 1.35; 0.13-2.67;P states fewer fully vaccinated 0.59; 0.16-1.02;P .007). pandemic–related was higher among 0.22; 0.08-0.37;P .003), 0.33; 0.22-0.43;P .001), 0.17; 0.09-0.25;P 0.15; 0.09-0.21) treatment 0.11; 0.06-0.16). Inability afford associated increased sadness 1.50; 0.06-2.93;P .04). States later eligibility dates for all 0.16; 0.01-0.31;P .03) positive affect −1.78; −3.39 −0.18;P children.

Conclusions Relevance

Results this suggest a adverse minority groups, which may be improved by addressing modifiable (food unemployment, services, parental supervision) deprivation, job protection, vaccination)

Language: Английский

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Patterns of Social Determinants of Health and Child Mental Health, Cognition, and Physical Health

JAMA Pediatrics, Journal Year: 2023, Volume and Issue: 177(12), P. 1294 - 1294

Published: Oct. 16, 2023

Importance Social determinants of health (SDOH) influence child health. However, most previous studies have used individual, small-set, or cherry-picked SDOH variables without examining unbiased computed patterns from high-dimensional factors to investigate associations with mental health, cognition, and physical Objective To identify estimate their children’s mental, cognitive, developmental outcomes. Design, Setting, Participants This population-based cohort study included children aged 9 10 years at baseline caregivers enrolled in the Adolescent Brain Cognitive Development (ABCD) Study between 2016 2021. The ABCD includes 21 sites across 17 states. Exposures Eighty-four neighborhood-level, geocoded spanning 7 domains SDOH, including bias, education, infrastructure, natural environment, socioeconomic status, social context, crime drugs, were studied. Hierarchical agglomerative clustering was patterns. Main Outcomes Measures Associations (internalizing externalizing behaviors) suicidal behaviors, cognitive function (performance, reading skills), (body mass index, exercise, sleep disorder) estimated using mixed-effects linear logistic regression models. Results Among 504 (baseline median [SD] age, 9.9 [0.6] years; 5510 boys [52.5%] 4994 girls [47.5%]; 229 Asian [2.2%], 1468 Black [14.0%], 2128 Hispanic [20.3%], 5565 White [53.0%], 1108 multiracial [10.5%]), 4 identified: pattern 1, affluence (4078 [38.8%]); 2, high-stigma environment (2661 [25.3%]); 3, high deprivation (2653 4, drug sales, low population density (1112 [10.6%]). distinctly associated Children exposed (SDOH 3) showed worst profiles, manifesting more internalizing (β = 0.75; 95% CI, 0.14-1.37) 1.43; 0.83-2.02) problems, lower performance, adverse Conclusions shows that an quantitative analysis multidimensional can permit determination how are outcomes relative other categories. These findings suggest need determine whether improvement conditions enhance

Language: Английский

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Characterizing the dimensional structure of early-life adversity in the Adolescent Brain Cognitive Development (ABCD) Study

Developmental Cognitive Neuroscience, Journal Year: 2023, Volume and Issue: 61, P. 101256 - 101256

Published: May 18, 2023

Early-life adversity has profound consequences for youth neurodevelopment and adjustment; however, experiences of are heterogeneous interrelated in complex ways that can be difficult to operationalize organize developmental research. We sought characterize the underlying dimensional structure co-occurring adverse among a subset (ages 9–10) from Adolescent Brain Cognitive Development (ABCD) Study (N = 7115), community sample United States. identified 60 environmental experiential variables reflect experiences. Exploratory factor analysis 10 robust dimensions early-life co-occurrence, corresponding conceptual domains such as caregiver substance use biological separation, psychopathology, lack support, socioeconomic disadvantage / neighborhood safety. These demonstrated distinct associations with internalizing problems, externalizing cognitive flexibility, inhibitory control. Non-metric multidimensional scaling characterized qualitative similarity dimensions. Results supported nonlinear three-dimensional representing adversity, including continuous gradients "perspective", "environmental uncertainty", "acts omission/commission". Our findings suggest there co-occurrence ABCD at baseline, resulting may have unique implications behavior.

Language: Английский

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Causal Relationships Between Screen Use, Reading, and Brain Development in Early Adolescents

Advanced Science, Journal Year: 2024, Volume and Issue: 11(11)

Published: Jan. 2, 2024

Abstract The rise of new media has greatly changed the lifestyles, leading to increased time on these platforms and less spent reading. This shift particularly profound impacts early adolescents, who are in a critical stage brain development. Previous studies have found associations between screen use mental health, but it remains unclear whether is direct cause outcomes. Here, Adolescent Brain Cognitive Development (ABCD) dataset utlized examine causal relationships results revealed adverse effects language ability specific behaviors while reading positive their volume frontal temporal regions. Interestingly, identified as result, rather than cause, certain such rule‐breaking aggressive behaviors. Furthermore, analysis uncovered an indirect influence use, mediated by changes habits, These findings provide evidence for influences development highlight importance monitoring related habit change children.

Language: Английский

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Comparing two measures of neighborhood quality and internalizing and externalizing behaviors in the adolescent brain cognitive development study

Social Psychiatry and Psychiatric Epidemiology, Journal Year: 2024, Volume and Issue: 59(8), P. 1321 - 1334

Published: Feb. 2, 2024

Language: Английский

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Prevalence and Patterns of Social Media Use in Early Adolescents

Academic Pediatrics, Journal Year: 2025, Volume and Issue: unknown, P. 102784 - 102784

Published: Jan. 1, 2025

To describe patterns of social media use, including underage (under 13 years) use and sex differences, in a diverse, national sample early adolescents the U.S. We analyzed data Adolescent Brain Cognitive Development Study (2019-2021, Year 3), which includes Specifically, using chi-squared t-tests, we compared across demographic characteristics stratified by age sex. In 10,092 11-to-15-year-old adolescents, 69.5% had at least one account; among users, most common platforms were TikTok (67.1%), YouTube (64.7%), Instagram (66.0%). A majority (63.8%) participants under years (minimum requirement) reported use. Under-13 users an average 3.38 accounts, with 68.2% having accounts 39.0% saying was site they used most. Females higher TikTok, Snapchat, Instagram, Pinterest, while males Reddit. Additionally, 6.3% secret account hidden from their parents' knowledge. Our findings reveal high prevalence rate adolescence. These can inform current policies legislation aimed more robust verification measures, minimum requirements, enhancement parental controls on media. Clinicians counsel about potential risks adolescent old accounts.

Language: Английский

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Associations between socioeconomic status and mental health trajectories during early adolescence: Findings from the Adolescent Brain Cognitive Development study

JCPP Advances, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 25, 2025

Abstract Background Low socioeconomic status (SES) during childhood is associated with higher levels of youth psychopathology. However, limited longitudinal work has examined the role both household and neighborhood SES in shaping mental health trajectories over time using population‐based data. The goal present study was to characterize associations between changes problems early adolescence. Methods We investigated independent joint income‐to‐needs ratio, parent educational attainment, material hardship, disadvantage internalizing, externalizing, attention symptom data from Adolescent Brain Cognitive Development (ABCD) Study. Given sex‐based differences ABCD study, analyses were conducted separately males females. assessed at baseline youth‐reported across six time‐points age 10–13 years ( M = 10.4, SD 0.63 years; first 6‐month follow‐up; N 9488). Results Main effects indicated that, general, high lower symptoms. longitudinally, increases relative SES. In females, while internalizing symptoms increased all income‐to‐needs, association most positive B 0.036, SE 0.008, p < 0.001). males, positively predicted externalizing 0.022, 0.007, 0.002) 0.023, 0.001) trajectories, linked income‐to‐needs. Two‐way interactions indicators predicting non‐significant. Conclusion Our finding that lower‐SES backgrounds exhibited adolescence contrasts findings prior cross‐sectional studies. are on rise landscape risk for psychopathology changing. More research needed understand how contributes resilience transition

Language: Английский

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Five recommendations for using large-scale publicly available data to advance health among American Indian peoples: the Adolescent Brain and Cognitive Development (ABCD) StudySM as an illustrative case

Neuropsychopharmacology, Journal Year: 2022, Volume and Issue: 48(2), P. 263 - 269

Published: Nov. 16, 2022

Abstract American Indian and Alaska Native (AIAN) populations have suffered a history of exploitation abuse within the context mental health research related fields. This is rooted in assimilation policies, historical trauma, cultural loss, promulgated through discrimination disregard for traditional culture community knowledge. In recognition this history, it imperative researchers to utilize culturally sensitive approaches that consider tribal communities better address issues AIAN individuals. The public availability data from large-scale studies creates both opportunities challenges when studying populations. manuscript has two goals; first, showcase an example problematic use Adolescent Brain Cognitive Development (ABCD) Study SM promulgate stereotypes about individuals and, second, partnership with collaborators Cherokee Nation, we provide five recommendations utilizing publicly available datasets advance Specifically, argue consideration (1) heterogeneity represented, (2) importance focusing on well-being, (3) engagement relevant leaders, (4) ongoing injustices, (5) regulatory agencies or review boards. These are founded principles broader indigenous efforts emphasizing community-engaged Indigenous Data Sovereignty Governance.

Language: Английский

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Changes in patterns of age-related network connectivity are associated with risk for schizophrenia

Proceedings of the National Academy of Sciences, Journal Year: 2023, Volume and Issue: 120(32)

Published: Aug. 1, 2023

Alterations in fMRI-based brain functional network connectivity (FNC) are associated with schizophrenia (SCZ) and the genetic risk or subthreshold clinical symptoms preceding onset of SCZ, which often occurs early adulthood. Thus, age-sensitive FNC changes may be relevant to SCZ risk-related FNC. We used independent component analysis estimate from childhood adulthood 9,236 individuals. To capture individual features more accurately than single-session fMRI, we studied an average three fMRI scans per individual. identify potential familial changes, compared age-related first-degree relatives patients mostly including unaffected siblings (SIB) neurotypical controls (NC) at same age stage. Then, examined how polygenic scores for influenced patterns. Finally, investigated patterns adult (oSCZ) young individuals subclinical psychotic (PSY). Age-sensitive emerge during adolescence adulthood, but not before. Young SIB always followed older NC patterns, decreased a cerebellar-occipitoparietal circuit increased two prefrontal-sensorimotor circuits when NC. Two these alterations were also found oSCZ, one exhibiting reversed pattern. All linked unrelated (R

Language: Английский

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