Spotlight on therapeutic efficiency of green synthesis metals and their oxide nanoparticles in periodontitis

Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)

Published: Jan. 5, 2024

Abstract Periodontitis, one of the most prevalent dental diseases, causes loss bone and gum tissue that hold teeth in place. Several bacteria, commonly present clinically healthy oral cavities, may induce perpetuate periodontitis when their concentration rises gingival sulcus. Antibacterial effect against various Gram-negative Gram-positive including pathogenic drug-resistant ones, has been shown for several distinct transient metal oxide NPs. Therefore, NPs be used biomedicine to treat periodontal problems nanotechnology inhibit development microorganisms. Instead using harmful chemicals or energy-intensive machinery, biosynthesis nanoparticles (NPs) suggested. To produce NPs, ideal technique is “Green” synthesis because its low toxicity safety human health environment. Gold (AuNPs) appear less toxic mammalian cells than other nanometals antibacterial activity not dependent on reactive oxygen species (ROS). AgNPs also possess chemical stability, catalytic activity, superior electrical thermal conductivity, name a few advantageous characteristics. It was observed zinc (ZnO) copper (Cu) exhibited discernible inhibitory effects gram-positive gram-negative bacterial strains, respectively. ZnO demonstrated bactericidal microorganisms responsible periodontitis. Medications containing magnetic are highly effective multidrug-resistant fungal infections. The titanium dioxide (TiO 2 ) implicated elevating salivary peroxidase individuals diagnosed with chronic Furthermore, specific metallic have potential enhance antimicrobial efficacy treatments combined. these as well only some metals oxides synthesized environmentally friendly ways therapeutic benefits Graphical

Language: Английский

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Current natural bioactive materials in bone and tooth regeneration in dentistry: a comprehensive overview

Journal of Materials Research and Technology, Journal Year: 2021, Volume and Issue: 13, P. 2078 - 2114

Published: June 11, 2021

Tissue regeneration is a vital phenomenon in the skeletal system of human beings during their life span. The structure bony architecture and teeth are highly dependent to this ongoing procedure maintain functional form. Regarding fundamental function our system, all involved components at constant risk for injuries deformations throughout life. Therefore, modern medicine, promotion bone tooth has become critical counter measure correct these acquired defects. There numerous ways address related erosive pathologies but utilization natural compounds gained immense popularity recent years. These materials provide broad spectrum therapeutic agents with variety biological characteristics. In review, comprehensive exploration been implemented extract categorize relevant scientific evidence on issue, based source candidates potential clinical indications. Database searching presented considerable data pool more than 300 references field. According results, proposed items can be categorized two major groups including scaffolding osteogenesis (or dentinogenesis) induction. applicability number them properly demonstrated trials rest, examinations required reach conclusive decision.

Language: Английский

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Bite Force Transducers and Measurement Devices

Frontiers in Bioengineering and Biotechnology, Journal Year: 2021, Volume and Issue: 9

Published: April 9, 2021

In dental research, bite force has become an important curative effect evaluation index for tooth restoration, periodontal treatment, and orthodontic treatment. Bite is parameter to evaluate the efficacy of masticatory system. Physicians obtain therapeutic basis occlusal adjustment by measuring dynamic changes in contact at different stages treatment objectively effect. At present, many devices are used record force. Most these use transducers detect force, such as strain gauge transducers, piezoresistive piezoelectric optical fiber pressure-sensitive films. This article summarizes various equipment related materials characteristics this equipment. It provides a reference physicians make choices during clinical process same time development new measurement materials.

Language: Английский

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Synthetic Calcium–Phosphate Materials for Bone Grafting

Polymers, Journal Year: 2023, Volume and Issue: 15(18), P. 3822 - 3822

Published: Sept. 19, 2023

Synthetic bone grafting materials play a significant role in various medical applications involving regeneration and repair. Their ability to mimic the properties of natural promote healing process has contributed their growing relevance. While calcium–phosphates composites with polymers biopolymers are widely used clinical experimental research, diverse range available polymer-based poses challenges selecting most suitable grafts for successful This review aims address fundamental issues biology while providing clear perspective on principles guiding development synthetic materials. In this study, we delve into basic underlying creation explore mechanisms formation biologically important complexes structures associated constituent parts these Additionally, offer comprehensive information application active substances enhance bioactivity By presenting insights, our enables deeper understanding processes facilitated by composites.

Language: Английский

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Therapeutic Potential of Flavonoids and Tannins in Management of Oral Infectious Diseases—A Review

Molecules, Journal Year: 2022, Volume and Issue: 28(1), P. 158 - 158

Published: Dec. 24, 2022

Medicinal plants are rich sources of valuable molecules with various profitable biological effects, including antimicrobial activity. The advantages herbal products their effectiveness, relative safety based on research or extended traditional use, and accessibility without prescription. Extensive irrational usage antibiotics since discovery in 1928 has led to the increasing expiration effectiveness due antibacterial resistance. Now, medical is facing a big challenging mission find effective safe therapies replace inactive drugs. Over years, one fields that remained most available area natural products: medicinal metabolites, which could serve as active substances fight against microbes be considered models drug design. This review presents selected flavonoids (such apigenin, quercetin, kaempferol, kurarinone, morin) tannins (including oligomeric proanthocyanidins, gallotannins, ellagitannins, catechins, epigallocatechin gallate), but also these compounds potential therapeutic agents oral infectious diseases usages such Agrimonia eupatoria L., Hamamelis virginiana Matricaria chamomilla Vaccinium myrtillus Quercus robur Rosa gallica Rubus idaeus Potentilla erecta (L.). Some presented extracts already successfully used maintain health, main additive ingredient toothpastes mouthwashes. Others promising for further future applications.

Language: Английский

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Potential Impact of Prosthetic Biomaterials on the Periodontium: A Comprehensive Review

Molecules, Journal Year: 2023, Volume and Issue: 28(3), P. 1075 - 1075

Published: Jan. 20, 2023

The success of a prosthetic treatment is closely related to the periodontal health individual. aim this article was review and present importance restorative materials on condition periodontium, changes that occur in composition subgingival microbiota levels inflammatory markers gingival crevicular fluid. Articles influence different proinflammatory cytokines were searched for using keywords "prosthetic biomaterials", "fixed prosthesis", "periodontal health", "subgingival microbiota", biomarkers" "gingival fluid" PubMed/Medline, Science Direct, Scopus Google Scholar. type material used prosthesis fabrication together with poor marginal internal fit can result microbiota, as well increased accumulation retention dentobacterial plaque, thus favoring development disease failure. Biological have helped understand response tissues main purpose improving their clinical application patients who need them. Metal-free ceramic prostheses induce lower regardless method; however, use CAD/CAM systems recommended fabrication. In addition, it presumed metal-ceramic cause producing more dysbiotic biofilm higher prevalence periodontopathogenic bacteria, which may further favor deterioration.

Language: Английский

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Herbal remedies for oral and dental health: a comprehensive review of their multifaceted mechanisms including antimicrobial, anti-inflammatory, and antioxidant pathways

Inflammopharmacology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 5, 2025

Abstract Across diverse cultures, herbal remedies have been used to alleviate oral discomfort and maintain dental hygiene. This review presents studies on with remarkable antimicrobial, anti-inflammatory, antioxidant, anticancer, anticaries, analgesic, healing properties. The manuscripts demonstrate the depth of scientific inquiry into for management various health conditions. These include gingivitis, ulcers, mucositis, periodontitis, pathogens, carcinoma, xerostomia, caries. Researchers investigated phytochemical pharmacological properties plant-derived compounds their extracts evaluated interactions pathogens inflammatory processes. convergence traditional knowledge rigorous investigation offers a compelling narrative, fostering deeper understanding as viable alternatives conventional interventions. work has potential provide patients access gentle, yet effective solutions, simultaneously offer professionals opportunity enrich knowledge, ability personalized, holistic care. highlights symbiotic relationship between medicine understanding, emphasizing importance disseminating this benefit both practitioners patients, enabling evidence-based decision-making in exploration promising alternative, potentially mitigating some these side effects while promoting more natural manner.

Language: Английский

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Tissue engineering innovations to enhance osseointegration in immediate dental implant loading: A narrative review

Cell Biochemistry and Function, Journal Year: 2024, Volume and Issue: 42(2)

Published: March 1, 2024

Abstract The demand for efficient and accelerated osseointegration in dental implantology has led to the exploration of innovative tissue engineering strategies. Immediate implant loading reduces treatment duration necessitates robust ensure long‐term success. This review article discusses current studies innovations enhancing immediate recent decade. Keywords “tissue engineering,” “osseointegration,” “immediate loading,” related terms were systematically searched. highlights potential bioactive materials growth factor delivery systems promoting osteogenic activity accelerating bone regeneration. vivo experiment demonstrates significantly improved experimental group compared traditional techniques, as evidenced by histological analyses biomechanical assessments. It is possible revolutionize outcomes patient satisfaction implants integrating factors.

Language: Английский

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The current techniques in dorsal augmentation rhinoplasty: a comprehensive review

Maxillofacial Plastic and Reconstructive Surgery, Journal Year: 2024, Volume and Issue: 46(1)

Published: April 28, 2024

An essential aspect of rhinoplasty is the enhancement nasal dorsal contour by performing augmentation (DA) rhinoplasty. A wide range techniques are available for DA as demand aesthetic refinement grows. This review aims to provide a comprehensive overview current used in

Language: Английский

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Full-ceramic resin-bonded fixed dental prostheses: A systematic review

Journal of Applied Biomaterials & Functional Materials, Journal Year: 2024, Volume and Issue: 22

Published: Jan. 1, 2024

Despite the development of implant-supported prostheses, there are still patients for whom conservative treatments such as resin-bonded fixed dental prostheses (RBFDPs) more appropriate. This study’s objective was to analyze available research on full-ceramic RBFDPs. In this study, Web Science, MEDLINE/PubMed, Scopus, Embase, Cochrane Library, and Google Scholar databases were searched articles published in English between 2010 2020. A total 14 studies reviewed based eligibility criteria. The results showed that using a cantilever design with one abutment had an advantage over two abutments. Additionally, it proposed preparations designed retentive aids, proximal box, groove, pinhole, could improve RBFDP survival rates. IPS e.max ZirCAD, In-Ceram alumina, zirconia CAD/CAM most commonly used framework materials. Most air abrasion, salinization, or hydrofluoric acid surface treatment. Adhesive resin cements frequently type cement. rate ceramics (85.3%–94.8%) lower than ZirCAD. Debonding, followed by fracture, leading cause failure. Following 3–10 years follow-up, percentage all-ceramic RBFDPs ranged from 76% 100%. Although have demonstrated satisfactory success treatment, long-term follow-ups higher sample sizes clinical required gain reliable outcomes various designs.

Language: Английский

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