Occurrence, sources and conventional treatment techniques for various antibiotics present in hospital wastewaters: A critical review

TrAC Trends in Analytical Chemistry, Journal Year: 2020, Volume and Issue: 129, P. 115921 - 115921

Published: June 5, 2020

Language: Английский

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An assessment of hospital wastewater and biomedical waste generation, existing legislations, risk assessment, treatment processes, and scenario during COVID-19

Journal of Environmental Management, Journal Year: 2022, Volume and Issue: 308, P. 114609 - 114609

Published: Jan. 26, 2022

Language: Английский

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A review of emerging micro-pollutants in hospital wastewater: Environmental fate and remediation options

Results in Engineering, Journal Year: 2022, Volume and Issue: 16, P. 100671 - 100671

Published: Sept. 28, 2022

Hospitals played vital role in the maintenance and sustenance of human health. However, hospital activities generate high volume toxic solid liquid containing diverse inorganic, organic microbial wastes released untreated into ecosystem. The management wastewater particular has been a major source concern due to presence unregulated emerging micro-pollutants at concentrations range ng/L μg/L. These pollutants low concentration exert different potential health effects on aquatic species. In this review, formation, composition, properties ecotoxicology selected (Norfloxacin, Ofloxacin, Ciprofloxacin, Clofibric acid Carbamazepine) were reviewed. review also elucidates detection quantification micropollutants by Spectrophotometry techniques, Gas Chromatography, Ion Chromatography-Mass spectrometry, High-Performance Liquid Chromatography. Furthermore, treatment through physical, biological, chemical, adsorption advanced oxidation processes such as photocatalysis photo-Fenton including their operational mechanism provided. chemistry degradation several intermediates It was found that conventional methods are not designed for effective removal these because they exist mixtures very exerts toxicological effects. reveals no single technology can effectively detoxify wastewater, instead combination (phototcatalytic/adsorption or photo-fenton/adsorption) most appropriate treatment. Finally, regular monitoring determination physicochemical ecotoxicological parameters recommended.

Language: Английский

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Anticancer drugs in wastewater and natural environments: A review on their occurrence, environmental persistence, treatment, and ecological risks

Journal of Hazardous Materials, Journal Year: 2023, Volume and Issue: 447, P. 130818 - 130818

Published: Jan. 18, 2023

Language: Английский

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A DFT study of pure and Si-decorated boron nitride allotrope Irida monolayer as an effective sensor for hydroxyurea drug

Journal of Molecular Graphics and Modelling, Journal Year: 2025, Volume and Issue: 136, P. 108958 - 108958

Published: Jan. 22, 2025

Language: Английский

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Environmental fate of pharmaceutical compounds and antimicrobial-resistant bacteria in hospital effluents, and contributions to pollutant loads in the surface waters in Japan

The Science of The Total Environment, Journal Year: 2018, Volume and Issue: 657, P. 476 - 484

Published: Dec. 3, 2018

Language: Английский

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Cytostatic pharmaceuticals as water contaminants

European Journal of Pharmacology, Journal Year: 2019, Volume and Issue: 866, P. 172816 - 172816

Published: Nov. 20, 2019

Due to the growing problem of cancer diseases, cytostatic drugs have become a great environmental threat. Their main sources are hospital effluents, household discharge and drug manufacturers. As these compounds not removed during wastewater treatment with sufficient efficiency, they found in surface, ground drinking water quantities up 2.12 × 10−4 mg/l. The current knowledge about their harmful influence on humans does indicate significant risk health consumers, although it points certain groups (children lactating women) particular. In aquatic organisms, anticancer detected concentrations can cause chronic toxicity detrimental impact genetic material. acute effect is less likely. HC5 value calculated by us (the concentration at which 5% species potentially affected) equalling 2.1 mg/l shows that real hazardous contaminants for environment. It indicates effective elimination cytostatics from still requires intensive research.

Language: Английский

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Removal of doxorubicin hydrochloride using Fe3O4 nanoparticles synthesized by euphorbia cochinchinensis extract

Chemical Engineering Journal, Journal Year: 2018, Volume and Issue: 353, P. 482 - 489

Published: July 25, 2018

Language: Английский

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Anticancer drugs in the aquatic ecosystem: Environmental occurrence, ecotoxicological effect and risk assessment

Environment International, Journal Year: 2021, Volume and Issue: 153, P. 106543 - 106543

Published: April 2, 2021

Anticancer drugs are a group of therapeutic agents used to enhance cell death in targeted types neoplasia. Because frequent use and eventual discharge, they have been often detected wastewater from pharmaceutical factories hospitals, domestic wastewater, surface waters. The occurrence these aquatic ecosystems their effects on organisms poorly characterized. This review focuses the global major classes anticancer water sediments freshwater ecotoxicological at different biological levels. While availability data is fairly limited, concentrations most range < 2 ng/L 762 µg/L receiving water, while levels sludge vary 0.25 42.5 µg/kg. Their detection frequencies were 58%, 52% (78%) 59% hospital treatment plant effluents (influents) respectively. Predicted log Kow values vincristine, imatinib mesylate tamoxifen higher than 3 estimated half-lives>60 d waters using quantitative structure-activity relationship models, indicating high potential for persistence bioaccumulation. Based species sensitivity distribution evaluation 9 compounds, crustaceans sensitive drugs. hazardous compound cisplatin which has hazard concentration 5th percentile. For Daphnia magna, acute toxicities ranked as platinum complexes > endocrine therapy antibiotics antimetabolite alkylating agents. Using quotient analysis based primarily lowest observed effect (LOECs), cyclophosphamide, cisplatin, 5-fluorouracil, mesylate, bicalutamide, etoposide paclitaxel highest organisms. Further research needed identify appropriate chronic endpoints risk assessment thresholds well better understand mechanisms action multigenerational toxicity, trophic transfer ecosystems.

Language: Английский

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Environmental risk assessment of widely used anticancer drugs (5-fluorouracil, cisplatin, etoposide, imatinib mesylate)

Water Research, Journal Year: 2019, Volume and Issue: 164, P. 114953 - 114953

Published: Aug. 4, 2019

Language: Английский

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