Gold nanoparticles and gold nanorods in the landscape of cancer therapy

Molecular Cancer, Journal Year: 2023, Volume and Issue: 22(1)

Published: June 21, 2023

Abstract Cancer is a grievous disease whose treatment requires more efficient, non-invasive therapy, associated with minimal side effects. Gold nanoparticles possessing greatly impressive optical properties have been forerunner in bioengineered cancer therapy. This theranostic system has gained immense popularity and finds its application the field of molecular detection, biological imaging, cell targeting, etc. The photothermal property nanoparticles, especially gold nanorods, causes absorption light incident by source, transforms it into heat, resulting tumor destruction. review describes different features summarizes advance research done for precisely nanorods combating various cancers including breast, lung, colon, oral, prostate, pancreatic cancer.

Language: Английский

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Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches

Molecular Cancer, Journal Year: 2023, Volume and Issue: 22(1)

Published: Oct. 6, 2023

Abstract Skin cancer is a global threat to the healthcare system and estimated incline tremendously in next 20 years, if not diagnosed at an early stage. Even though it curable stage, novel drug identification, clinical success, resistance another major challenge. To bridge gap bring effective treatment, important understand etiology of skin carcinoma, mechanism cell proliferation, factors affecting growth, resistance. The current article focusses on understanding structural diversity cancers, treatments available till date including phytocompounds, chemotherapy, radiotherapy, photothermal therapy, surgery, combination molecular targets associated with growth metastasis, special emphasis nanotechnology-based approaches for downregulating deleterious disease. A detailed analysis respect types nanoparticles their scope overcoming multidrug as well trials has been discussed. Graphical

Language: Английский

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Advancements in dextran-based nanocarriers for treatment and imaging of breast cancer

International Journal of Pharmaceutics, Journal Year: 2023, Volume and Issue: 643, P. 123276 - 123276

Published: July 27, 2023

Language: Английский

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Emerging potential of 5-Fluorouracil-loaded chitosan nanoparticles in cancer therapy

Journal of Drug Delivery Science and Technology, Journal Year: 2023, Volume and Issue: 82, P. 104371 - 104371

Published: March 15, 2023

Language: Английский

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New opportunities for RGD-engineered metal nanoparticles in cancer

Molecular Cancer, Journal Year: 2023, Volume and Issue: 22(1)

Published: May 25, 2023

The advent of nanotechnology has opened new possibilities for bioimaging. Metal nanoparticles (such as gold, silver, iron, copper, etc.) hold tremendous potential and offer enormous opportunities imaging diagnostics due to their broad optical characteristics, ease manufacturing technique, simple surface modification. arginine-glycine-aspartate (RGD) peptide is a three-amino acid sequence that seems have considerably greater ability adhere integrin adhesion molecules exclusively express on tumour cells. RGD peptides act the efficient tailoring ligand with variety benefits including non-toxicity, precision, rapid clearance, etc. This review focuses possibility non-invasive cancer using metal assistance.

Language: Английский

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Hyaluronic acid-functionalized lipoplexes and polyplexes as emerging nanocarriers for receptor-targeted cancer therapy

Environmental Research, Journal Year: 2023, Volume and Issue: 233, P. 116506 - 116506

Published: June 25, 2023

Language: Английский

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Self-nanoemulsifying drug delivery system for pancreatic cancer

European Polymer Journal, Journal Year: 2023, Volume and Issue: 190, P. 111993 - 111993

Published: March 15, 2023

Language: Английский

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Targeted therapy of breast tumor by PLGA-based nanostructures: The versatile function in doxorubicin delivery

Environmental Research, Journal Year: 2023, Volume and Issue: 233, P. 116455 - 116455

Published: June 24, 2023

Language: Английский

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Understanding the Novel Approach of Nanoferroptosis for Cancer Therapy

Nano-Micro Letters, Journal Year: 2024, Volume and Issue: 16(1)

Published: May 2, 2024

As a new form of regulated cell death, ferroptosis has unraveled the unsolicited theory intrinsic apoptosis resistance by cancer cells. The molecular mechanism depends on induction oxidative stress through excessive reactive oxygen species accumulation and glutathione depletion to damage structural integrity Due their high loading tunability, nanocarriers can escort delivery ferro-therapeutics desired site enhanced permeation or retention effect active targeting. This review shed light necessity iron in growth fascinating features regulating cycle metastasis. Additionally, we discussed ferroptosis-mediated therapy using nanoplatforms chemical basis overcoming barriers therapy.

Language: Английский

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PLGA nanomedical consignation: A novel approach for the management of prostate cancer

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 652, P. 123808 - 123808

Published: Jan. 14, 2024

Language: Английский

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