Advances in the polymeric nanoparticulate delivery systems for RNA therapeutics DOI

Sristi,

Waleed Hassan Almalki, Ritu Karwasra

et al.

Progress in molecular biology and translational science, Journal Year: 2024, Volume and Issue: unknown, P. 219 - 248

Published: Jan. 1, 2024

Language: Английский

Gold nanoparticles and gold nanorods in the landscape of cancer therapy DOI Creative Commons
Prashant Kesharwani,

Ruiyang Ma,

Liang Sang

et al.

Molecular Cancer, Journal Year: 2023, Volume and Issue: 22(1)

Published: June 21, 2023

Abstract Cancer is a grievous disease whose treatment requires more efficient, non-invasive therapy, associated with minimal side effects. Gold nanoparticles possessing greatly impressive optical properties have been forerunner in bioengineered cancer therapy. This theranostic system has gained immense popularity and finds its application the field of molecular detection, biological imaging, cell targeting, etc. The photothermal property nanoparticles, especially gold nanorods, causes absorption light incident by source, transforms it into heat, resulting tumor destruction. review describes different features summarizes advance research done for precisely nanorods combating various cancers including breast, lung, colon, oral, prostate, pancreatic cancer.

Language: Английский

Citations

164

Nanoparticle‐Based Photothermal Therapy for Breast Cancer Noninvasive Treatment DOI

Yao Xiong,

Yan Rao,

Jiawei Hu

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 10, 2023

Rapid advancements in materials science and nanotechnology, intertwined with oncology, have positioned photothermal therapy (PTT) as a promising noninvasive treatment strategy for cancer. The breast's superficial anatomical location aesthetic significance render breast cancer particularly pertinent candidate the clinical application of PTT following melanoma. This review comprehensively explores research conducted on various types nanoparticles employed elaborates their specific roles mechanisms action. integration existing therapies is scrutinized, underscoring its potential synergistic outcomes. Additionally, underlying consequential modifications to tumor microenvironment after are elaborated from medical perspective. Future directions suggested, an emphasis development integrative platforms that combine multiple therapeutic approaches optimization nanoparticle synthesis enhanced efficacy. goal push boundaries toward comprehensive, clinically applicable

Language: Английский

Citations

85

Nanomaterials-assisted photothermal therapy for breast cancer: State-of-the-art advances and future perspectives DOI Creative Commons
Sagnik Nag, Oishi Mitra, G. Tripathi

et al.

Photodiagnosis and Photodynamic Therapy, Journal Year: 2024, Volume and Issue: 45, P. 103959 - 103959

Published: Jan. 21, 2024

Breast cancer (BC) remains an enigmatic fatal modality ubiquitously prevalent in different parts of the world. Contemporary medicines face severe challenges remediating and healing breast cancer. Due to its spatial specificity nominal invasive therapeutic regime, photothermal therapy (PTT) has attracted much scientific attention down lane. PTT utilizes a near-infrared (NIR) light source irradiate tumor target intravenously or non-invasively, which is converted into heat energy over optical fibre. Dynamic progress nanomaterial synthesis was achieved with specialized visual, physicochemical, biological, pharmacological features make up for inadequacies expand horizon PTT. Numerous nanomaterials have substantial NIR absorption can function as efficient transducers. It achievable limit wavelength range absorbance peak specific by manipulating their synthesis, enhancing precision quality Along same lines, various are conjugated wide surface-modifying chemicals, including polymers antibodies, may modify persistence diminish toxicity concerns. In this article, we tend put forth insights fundamental conceptualizations on pre-existing advances upon conjugation biocompatible working synergy combat cancer, encompassing several strategies like immunotherapy, chemotherapy, photodynamic therapy, radiotherapy coupled Additionally, role mechanisms nanoparticles, well possible alternatives PTT, summarized distinctive integral aspect article.

Language: Английский

Citations

56

New opportunities for RGD-engineered metal nanoparticles in cancer DOI Creative Commons
Qin Wei,

Jyoti Chandra,

Mohammed A. S. Abourehab

et al.

Molecular Cancer, Journal Year: 2023, Volume and Issue: 22(1)

Published: May 25, 2023

The advent of nanotechnology has opened new possibilities for bioimaging. Metal nanoparticles (such as gold, silver, iron, copper, etc.) hold tremendous potential and offer enormous opportunities imaging diagnostics due to their broad optical characteristics, ease manufacturing technique, simple surface modification. arginine-glycine-aspartate (RGD) peptide is a three-amino acid sequence that seems have considerably greater ability adhere integrin adhesion molecules exclusively express on tumour cells. RGD peptides act the efficient tailoring ligand with variety benefits including non-toxicity, precision, rapid clearance, etc. This review focuses possibility non-invasive cancer using metal assistance.

Language: Английский

Citations

43

Nanotechnology-empowered strategies in treatment of skin cancer DOI

Jyoti Chandra,

Nazeer Hasan, Nazim Nasir

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 235, P. 116649 - 116649

Published: July 13, 2023

Language: Английский

Citations

42

Carbon nanotube-mediated platinum-based drug delivery for the treatment of cancer: Advancements and future perspectives DOI
Mohammad Sameer Khan, B.H. Jaswanth Gowda, Nazeer Hasan

et al.

European Polymer Journal, Journal Year: 2024, Volume and Issue: 206, P. 112800 - 112800

Published: Jan. 26, 2024

Language: Английский

Citations

24

Hyaluronic acid-functionalized lipoplexes and polyplexes as emerging nanocarriers for receptor-targeted cancer therapy DOI

Jyoti Chandra,

Nagashekhara Molugulu, Sivakumar Annadurai

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 233, P. 116506 - 116506

Published: June 25, 2023

Language: Английский

Citations

29

Self-nanoemulsifying drug delivery system for pancreatic cancer DOI

Neha Parveen,

Afsana Sheikh,

Mohammed A. S. Abourehab

et al.

European Polymer Journal, Journal Year: 2023, Volume and Issue: 190, P. 111993 - 111993

Published: March 15, 2023

Language: Английский

Citations

28

Understanding the theranostic potential of quantum dots in cancer management DOI
Mohammad Sameer Khan,

Afsana Sheikh,

Mohammed A. S. Abourehab

et al.

Materials Today Communications, Journal Year: 2023, Volume and Issue: 36, P. 106424 - 106424

Published: June 12, 2023

Language: Английский

Citations

26

Targeted therapy of breast tumor by PLGA-based nanostructures: The versatile function in doxorubicin delivery DOI

Tenzin Sonam Dongsar,

Tenzin Tsering Dongsar,

Nagashekhara Molugulu

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 233, P. 116455 - 116455

Published: June 24, 2023

Language: Английский

Citations

26