Materials Chemistry Frontiers, Journal Year: 2021, Volume and Issue: 5(15), P. 5595 - 5616
Published: Jan. 1, 2021
This review summarizes the development and utilization of marine polysaccharides in wound dressings. The commonly used are classified, types polysaccharide-based dressings described detail.
Language: Английский
Polymers, Journal Year: 2021, Volume and Issue: 13(7), P. 1105 - 1105
Published: March 30, 2021
Tissue engineering (TE) and regenerative medicine integrate information technology from various fields to restore/replace tissues damaged organs for medical treatments. To achieve this, scaffolds act as delivery vectors or cellular systems drugs cells; thereby, material is able colonize host cells sufficiently meet up the requirements of regeneration repair. This process multi-stage requires development components create desired neo-tissue organ. In several current TE strategies, biomaterials are essential components. While polymers established their use biomaterials, careful consideration environment interactions needed required in selecting a polymer given application. Depending on scaffold materials can be natural synthetic origin, degradable nondegradable. this review, an overview possible composite with physicochemical properties including biocompatibility, biodegradability, morphology, mechanical strength, pore size, porosity discussed. The fabrication techniques few commercially available biopolymers also tabulated.
Language: Английский
Citations
714
International Journal of Biological Macromolecules, Journal Year: 2022, Volume and Issue: 218, P. 930 - 968
Published: July 24, 2022
Language: Английский
Citations
265
Advanced Fiber Materials, Journal Year: 2022, Volume and Issue: 4(5), P. 1027 - 1057
Published: June 30, 2022
Language: Английский
Citations
154
Advanced Fiber Materials, Journal Year: 2022, Volume and Issue: 5(1), P. 107 - 129
Published: Nov. 2, 2022
Language: Английский
Citations
78
Advanced Functional Materials, Journal Year: 2023, Volume and Issue: 33(49)
Published: Sept. 7, 2023
Abstract Hyaluronic acid (HA) is an attractive anionic polysaccharide polymer with inherent pharmacological properties and versatile chemical groups for modification. Due to their water retention ability, biocompatibility, biodegradation, cluster of differentiation‐44 targeting, highly designable capacity, HA hydrogels have been emerging biomaterial, showing tailoring performance in terms modifications hydrogel forms. Various preparation technologies developed the fabrication unique structures functions. They utilized diverse biomedical applications like drug delivery tissue engineering scaffolds. Herein, this review comprehensively summarizes derivatives different molecule weights functional modifications. Then various methods obtain forms nanogel, nanofiber, microparticle, microneedle patch, injectable hydrogel, scaffold are reviewed as well. The emphasis focused on shining these anti‐bacteria, anti‐inflammation, wound healing, cancer treatment, regenerative medicine, psoriasis diagnosis, etc. potentials prospects subsequently given inspire further investigation, aiming at accelerating product translation from research clinic.
Language: Английский
Citations
73
Journal of Applied Polymer Science, Journal Year: 2023, Volume and Issue: 141(1)
Published: Oct. 3, 2023
Abstract In recent years, there has been a significant focus on bioactive dressings suitable for treating chronic and acute wounds. Electrospinning nanofibers are considered advanced dressing options due to their high porosity permeability air water, effective barrier properties against external pathogens, excellent resemblance the extracellular matrix wound healing skin regeneration. This article reviews advancements in application of electrospinning healing. The review begins with an overview process methods. It then explores advantages disadvantages different synthetic natural polymers used preparation dressings. discussed this include collagen, gelatin, silk fibroin, chitosan, hyaluronic acid, sodium alginate. Additionally, delves into commonly like polyvinyl alcohol, chloride, polyethylene lactone, polylactide, polyurethane applications. Furthermore, examines blending create high‐performance also incorporation functional additives, such as antimicrobial agents, growth factors, extracts, expedite tissue repair. conclusion, is emerging technology that provides unique opportunities designing more care products.
Language: Английский
Citations
66
RSC Advances, Journal Year: 2024, Volume and Issue: 14(5), P. 3359 - 3378
Published: Jan. 1, 2024
Electrostatic spinning as a technique for producing nanoscale fibers has recently attracted increasing attention due to its simplicity, versatility, and loadability.
Language: Английский
Citations
33
Materials Today Bio, Journal Year: 2021, Volume and Issue: 13, P. 100201 - 100201
Published: Dec. 30, 2021
Injectable hydrogel has the advantage to fill defective area and thereby shows promise as therapeutic implant or cell/drug delivery vehicle for tissue repair. In this study, an injectable hyaluronic acid in situ dual-enzymatically cross-linked by galactose oxidase (GalOx) horseradish peroxidase (HRP) was synthesized optimized, effect of encapsulated with bone mesenchymal stem cells (BMSC) nerve growth factors (NGF) traumatic brain injury (TBI) mice investigated. Results from vitro experiments showed that either tyramine-modified hydrogels (HT) NGF loaded HT (HT/NGF) possessed good biocompatibility. More importantly, BMSC could facilitate survival proliferation endogenous neural probably neurotrophic release neuroinflammation regulation, consequently improved neurological function recovery accelerated repair process a C57BL/6 TBI model. All these findings highlight injectable, NGF-laden enormous potential other therapy.
Language: Английский
Citations
87
Frontiers in Bioengineering and Biotechnology, Journal Year: 2022, Volume and Issue: 10
Published: Dec. 1, 2022
Nanotechnology is one of the most promising technologies available today, holding tremendous potential for biomedical and healthcare applications. In this field, there an increasing interest in use polymeric micro/nanofibers construction structures. Due to its applications various fields like pharmaceutics biomedicine, electrospinning process has gained considerable attention producing nano-sized fibers. Electrospun nanofiber membranes have been used drug delivery, controlled release, regenerative medicine, tissue engineering, biosensing, stent coating, implants, cosmetics, facial masks, theranostics. Various natural synthetic polymers successfully electrospun into ultrafine Although biopolymers demonstrate exciting properties such as good biocompatibility, non-toxicity, biodegradability, they possess poor mechanical properties. Hybrid nanofibers from bio combine characteristics with those polymers, high strength stability. addition, a variety functional agents, nanoparticles biomolecules, can be incorporated create multifunctional hybrid nanofibers. remarkable nanofibers, latest research on unique highlighted study. Moreover, established fabrication techniques, especially electrospinning-based methods, well emerging strategies characterization are summarized. Finally, development application discussed.
Language: Английский
Citations
60
International Journal of Nanomedicine, Journal Year: 2022, Volume and Issue: Volume 17, P. 3913 - 3931
Published: Sept. 1, 2022
As a type of biological macromolecule, natural polysaccharides have been widely used in wound healing due to their low toxicity, good biocompatibility, degradability and reproducibility.Electrospinning is versatile simple technique for producing continuous nanoscale fibers from variety synthetic polymers.The application electrospun nanofibers as dressings has made great progress they are considered one the most effective dressings.This paper reviews preparation polysaccharide by electrospinning prospects field healing.A nanofibers, including chitosan, starch, alginate, hyaluronic acid introduced.The strategy functions promoting summarized.In addition, future challenges also discussed.
Language: Английский
Citations
59