Plants, plant‐derived compounds, probiotics, and postbiotics as green agents to fight against poultry coccidiosis: A review DOI Creative Commons
Pan Chen, Kaili Liu,

Tian-Xiang Yue

et al.

Animal Research and One Health, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 11, 2024

Abstract The intestinal tract is the main place for animals to digest food and absorb nutrients, which also serves as first line of defense against pathogens that invade internal environment. Therefore, normal structure function are essential animal health. Poultry coccidiosis an disease primarily caused by parasitization epithelial cells protozoa genus Eimeria . occurrence not only compromises integrity poultry but increases their susceptibility, thus posing a serious threat overall health productivity poultry. Nowadays, primary methods controlling preventing in anticoccidial drugs or live oocyst vaccines. However, use former may be associated with problems resistance drug residues, while latter cause damage significantly increase farming costs. For these reasons, it critical investigate green, safe, cost‐effective natural alternative strategies such phytochemicals probiotics well mitigating deleterious effects coccidial infections production. In this review, we aim summarize role, mechanisms, therapeutic potential products treatment lay theoretical foundation effective control.

Language: Английский

Ephedra sinica polysaccharide alleviates airway inflammations of mouse asthma-like induced by PM2.5 and ovalbumin via the regulation of gut microbiota and short chain fatty acid DOI
Junxi Liu,

Hong-Yu Yuan,

Yanan Li

et al.

Journal of Pharmacy and Pharmacology, Journal Year: 2022, Volume and Issue: 74(12), P. 1784 - 1796

Published: Oct. 27, 2022

Epidemiological investigations show that long-term exposure to PM2.5 is directly related asthma-like and other respiratory diseases. This study aims further explore the pharmacological effect of Ephedra sinica polysaccharide (ESP) on lung injury caused by atmospheric PM2.5.To achieve aim, we explored therapeutic ESP an aggravated mouse induced combined with ovalbumin (OVA), mechanisms underlying connection between gut microbiota function.Preliminary results showed alleviated symptoms allergic in mice; reduced number eosinophils BALF; levels serum Ig-E, IL-6, TNF-α, IL-1β. Further qRT-PCR detected inhibited NF-κB pathway. The final analysis 16S rRNA short chain fatty acid (SCFA) confirmed increased relative proportions Bacteroides, Lactobacillus, Prevotella, Butyricicoccus Paraprevotella, but decreased Enterococcus Ruminococcus; acetic acid, propionic butyric isobutyric valeric isovaleric isohexanic meanwhile.The has a potential for future therapeutical applications prevention treatment disease OVA via regulation SCFA.

Language: Английский

Citations

20
An exploration of alginate oligosaccharides modulating intestinal inflammatory networks via gut microbiota DOI Creative Commons
Zhikai Zhang, Xuejiang Wang, Feng Li

et al.

Frontiers in Microbiology, Journal Year: 2023, Volume and Issue: 14

Published: Jan. 26, 2023

Alginate oligosaccharides (AOS) can be obtained by acidolysis and enzymatic hydrolysis. The products different methods have structures physiological functions. AOS received increasing interest because of their many health-promoting properties. been reported to exert protective roles for intestinal homeostasis modulating gut microbiota, which is closely associated with inflammation, barrier strength, bacterial infection, tissue injury, biological activities. However, the in inflammation network remain not well understood. A review published reports may help us establish linkage that improve affecting T helper type 1 (Th1) Th2, Th9, Th17, Th22 regulatory (Treg) cells, secreted cytokines [the hub genes protein-protein interaction networks include interleukin-1 beta (IL-1β), IL-2, IL-4, IL-6, IL-10 tumor necrosis factor alpha (TNF-α)]

Language: Английский

Citations

11
Colonic in vitro fermentation of mycoprotein promotes shifts in gut microbiota, with enrichment of Bacteroides species DOI Creative Commons
Raffaele Colosimo, Hannah C. Harris, Jennifer Ahn‐Jarvis

et al.

Communications Biology, Journal Year: 2024, Volume and Issue: 7(1)

Published: March 5, 2024

Abstract Mycoprotein is a fungal-derived ingredient used for meat alternative products whose fungal cell walls are rich in dietary fibre (β-glucans and chitin) defines its structure. Several health benefits have been reported after mycoprotein consumption, however, little known about the impact of fermentation on gut microbiota. This study aims to identify changes microbiome composition microbial metabolites during colonic following simulated upper gastrointestinal digestion. Changes populations produced by were investigated compared plant (oat bran) an animal (chicken) comparator. In this model system, oat showed different but marked population chicken, which minimal differentiation. particular, Bacteroides species degrading β-glucans found abundance fibre. resulted short-chain fatty acid production comparable with chicken at 72 h. Significantly higher branched-chain amino acids observed fermentation. suggests that can promote profile. These results highlight unique structure digestive processes

Language: Английский

Citations

4
Reverse engineering the Gut-Brain Axis and microbiome-metabolomics for symbiotic/pathogenic balance in neurodegenerative diseases DOI Creative Commons
Muhammad Usman Munir, Syed Aoun Ali, Ka Hang Karen Chung

et al.

Gut Microbes, Journal Year: 2024, Volume and Issue: 16(1)

Published: Nov. 10, 2024

Deciphering the molecular communications along gut-brain axis can help in understanding pathophysiology of neurodegenerative diseases and exploiting gut microbiome for therapeutics. However, microbes their metabolites have a multifaceted role mediating both brain physiology pathology. There is lack how when this tipped what are those contributing factors, at local (gut) distal (neuronal) levels, that drive imbalance. Here we reviewed its context summarized different factors such as gut-microbial diversity, metabolites, native immune system integrity epithelial blood-brain barriers interconnected collectively define involvement gut-microbiome pathologies. It also underlines need multidisciplinary tools animal models to simultaneously reflect on many these better correlate with clinical observations data obtained from human biopsies fecal samples. Harnessing will herald paradigm shift medicine aging, emphasizing significance broader spectrum health disease.

Language: Английский

Citations

4
Plants, plant‐derived compounds, probiotics, and postbiotics as green agents to fight against poultry coccidiosis: A review DOI Creative Commons
Pan Chen, Kaili Liu,

Tian-Xiang Yue

et al.

Animal Research and One Health, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 11, 2024

Abstract The intestinal tract is the main place for animals to digest food and absorb nutrients, which also serves as first line of defense against pathogens that invade internal environment. Therefore, normal structure function are essential animal health. Poultry coccidiosis an disease primarily caused by parasitization epithelial cells protozoa genus Eimeria . occurrence not only compromises integrity poultry but increases their susceptibility, thus posing a serious threat overall health productivity poultry. Nowadays, primary methods controlling preventing in anticoccidial drugs or live oocyst vaccines. However, use former may be associated with problems resistance drug residues, while latter cause damage significantly increase farming costs. For these reasons, it critical investigate green, safe, cost‐effective natural alternative strategies such phytochemicals probiotics well mitigating deleterious effects coccidial infections production. In this review, we aim summarize role, mechanisms, therapeutic potential products treatment lay theoretical foundation effective control.

Language: Английский

Citations

4