mSystems,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 20, 2024
A
good
quality
egg
is
essential
for
a
successful
pregnancy
and
early
embryo
development.
Oocyte
development
vulnerable
to
environmental
exposures.
Bisphenol
S
(BPS)
widely
used
as
replacement
its
analog
bisphenol
A,
but
the
reproductive
toxicity
of
BPS
has
been
great
concern.
In
this
study,
we
showed
that
exposure
induces
dysbiosis
gut
microbiota,
which
further
leads
intestinal
permeability
inflammation,
ultimately
impairs
oocyte
quality.
More
importantly,
found
alginate
oligosaccharide
reshapes
microbiota
improve
homeostasis,
thereby
preventing
deleterious
effects
on
oocytes.
Overall,
study
not
only
demonstrates
intestine
oocytes
by
inducing
also
develops
preventive
strategy.
Food & Function,
Journal Year:
2024,
Volume and Issue:
15(19), P. 9632 - 9661
Published: Jan. 1, 2024
Metabolic
syndrome
(MetS)
is
a
disease
condition
incorporating
the
abnormal
accumulation
of
various
metabolic
components,
including
obesity,
insulin
resistance
and
glucose
tolerance,
hypertension,
atherosclerosis,
or
dyslipidemia.
World Journal of Biology Pharmacy and Health Sciences,
Journal Year:
2024,
Volume and Issue:
17(1), P. 014 - 022
Published: Jan. 11, 2024
Alginate
Oligosaccharides
(AOs)
are
bioactive
compounds
prepared
through
the
enzymatic
degradation
of
alginate
polysaccharides
by
lyase.
These
have
become
a
focus
growing
interest
in
scientific
community,
largely
because
their
array
attributes,
which
include
immunomodulatory,
antioxidant,
anti-inflammatory
and
prebiotic
effects.
This
review
critically
examines
current
literature
on
(AOs),
encompassing
vitro
studies,
animal
models
preliminary
human
clinical
trials.
It
also
addresses
safety
profiles
AOs,
focusing
toxicological
assessments,
to
provide
comprehensive
view
risk-to-benefit
ratio.
Additionally,
assesses
existing
information
regarding
impact
health.
aims
identify
research
gaps
outline
potential
future
directions
for
therapeutic
application.
Journal of obstetrics and women s diseases,
Journal Year:
2024,
Volume and Issue:
73(3), P. 27 - 39
Published: July 17, 2024
BACKGROUND:
A
microbial
imbalance
in
the
vaginal
biotope
leads
to
development
of
infections
and
is
associated
with
urinary
tract
infections.
The
ineffectiveness
therapy
frequent
recurrence
these
are
important
reasons
for
searching
alternative
treatment
strategies.
progressive
solution
this
issue
has
been
use
oral
probiotics
a
targeted
effect
on
intestinal
microflora.
AIM:
aim
study
was
evaluate
antagonistic
antibacterial
activity
probiotic
strains
Lactobacillus
rhamnosus
HN001
acidophilus
La-14,
which
components
probiotic,
against
opportunistic
microorganisms
origin,
while
assessing
sensitivity
antimicrobial
drugs.
MATERIALS
AND
METHODS:
La-14
included
Duogynal®
were
cultivated
grown
colonies
identified
using
matrix-assisted
laser
desorption/ionization
time-of-flight
mass
spectrometry
method
(Bruker
Daltonics
GmbH
Co.,
Germany).
To
antagonism
lactobacilli
pathogenic
microorganisms,
following
11
clinical
isolates
collected:
Escherichia
coli
(two
isolates),
Klebsiella
pneumoniae,
oxytoca,
Enterobacter
asburiae,
Proteus
mirabilis,
Citrobacter
freundii,
Staphylococcus
aureus,
Enterococcus
faecalis,
Streptococcus
agalactiae,
Candida
albicans.
assess
drugs,
Gram
Positive
AST
panel
(Autobio
Diagnostics
Ltd,
China)
used.
RESULTS:
When
co-cultivated
(Lactobacillus
La-14),
we
noted
decrease
pH
death
such
as
coli,
well
yeast-like
fungi
studying
antibiotic
resistance,
it
found
that
both
resistant
ampicillin,
vancomycin,
daptomycin,
clindamycin,
linezolid,
moxifloxacin,
nitrofurantoin,
oxacillin,
oritavancin,
penicillin,
rifampin,
teicoplanin,
tigecycline,
trimethoprim/sulfamethoxazole,
cefoxitin,
ceftarolin,
ciprofloxacin.
CONCLUSIONS:
contains
combination
two
pronounced
microorganisms.
These
most
drugs
used
widespread
practice,
may
be
basis
recommending
drug
together
prescribed
antibiotics
prevention
or
dysbiosis.
