Journal of environmental chemical engineering, Journal Year: 2024, Volume and Issue: 12(5), P. 113461 - 113461
Published: July 1, 2024
Language: Английский
Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(10), P. 2514 - 2514
Published: Oct. 23, 2023
Hydrogels prepared from natural polymer have attracted extensive attention in biomedical fields such as drug delivery, wound healing, and regenerative medicine due to their good biocompatibility, degradability, flexibility. This review outlines the commonly used hydrogel preparation, including cellulose, chitosan, collagen/gelatin, alginate, hyaluronic acid, starch, guar gum, agarose, dextran. The polymeric structure process/synthesis of polymers are illustrated, polymer-based hydrogels formation properties elaborated. Subsequently, applications based on tissue regeneration, other summarized. Finally, future perspectives them discussed. For polymers, novel technologies enzymatic biological methods been developed improve structural properties, development new natural-based or derivatives with high performance is still very important challenging. hydrogels, materials, like double-network hydrogel, multifunctional composite microrobots designed meet advanced requirements applications, strategies dual-cross-linking, microfluidic chip, micropatterning, 3D/4D bioprinting explored fabricate materials for applications. Overall, increasing interest strategies/methods fabrication highly desirable
Language: Английский
Citations
100
Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(7), P. 1829 - 1829
Published: June 26, 2023
Nanofiber scaffolds have emerged as a revolutionary drug delivery platform for promoting wound healing, due to their unique properties, including high surface area, interconnected porosity, excellent breathability, and moisture absorption, well spatial structure which mimics the extracellular matrix. However, use of nanofibers achieve controlled loading release still presents many challenges, with ongoing research exploring how load drugs onto nanofiber without loss activity control in specific spatiotemporal manner. This comprehensive study systematically reviews applications recent advances related drug-laden skin-wound management. First, we introduce commonly used methods preparation, electrostatic spinning, sol-gel, molecular self-assembly, thermally induced phase separation, 3D-printing techniques. Next, summarize polymers preparation utilizing scaffolds. We then review application drug-loaded considering different stages healing acts. Finally, briefly describe stimulus-responsive schemes scaffolds, other exciting systems.
Language: Английский
Citations
77
RSC Advances, Journal Year: 2023, Volume and Issue: 13(50), P. 35251 - 35291
Published: Jan. 1, 2023
Nanocomposite hydrogel biomaterials represent an exciting frontier in biomedicine, offering solutions to longstanding challenges.
Language: Английский
Citations
72
Advances in Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 324, P. 103095 - 103095
Published: Jan. 28, 2024
Direct ink writing (DIW) stands as a pioneering additive manufacturing technique that holds transformative potential in the field of hydrogel fabrication. This innovative approach allows for precise deposition inks layer by layer, creating complex three-dimensional structures with tailored shapes, sizes, and functionalities. By harnessing versatility hydrogels, DIW opens up possibilities applications spanning from tissue engineering to soft robotics wearable devices. comprehensive review investigates applied hydrogels its multifaceted applications. The paper introduces diverse range printing techniques while providing thorough exploration hydrogel-based printing. investigation aims explain progress made, challenges faced, trajectories lie ahead manufacturing. fundamental principles underlying are carefully examined, specifically focusing on rheological attributes parameters, prompting survey wide variety materials. These encompass both natural synthetic variations, all which can be effectively harnessed this purpose. Furthermore, explores latest biomedical areas, primary focus engineering, wound dressing, drug delivery systems. document not only consolidates existing state within context but also charts avenues further research breakthroughs.
Language: Английский
Citations
49
Surfaces and Interfaces, Journal Year: 2023, Volume and Issue: 41, P. 103178 - 103178
Published: July 14, 2023
Language: Английский
Citations
45
Materials Science and Engineering R Reports, Journal Year: 2024, Volume and Issue: 159, P. 100799 - 100799
Published: April 30, 2024
Alginate, a polymer mainly derived from seaweed, has garnered significant attention owing to its renewability, biocompatibility, biodegradability, and exceptional gel formation characteristics, rendering it highly versatile for numerous applications. Recognizing the imperative tailored bulk materials, this review scrutinizes processing methodologies of alginate-based materials delineates strategies improve their properties, encompassing ionic crosslinking, plasticization, hybridization with other polymers and/or fillers. It explores noteworthy blends natural like polysaccharides proteins, alongside fossil-based poly(vinyl alcohol). also examines composites incorporating various nanofillers such as cellulose nanoparticles, graphene, nanoclays. The techniques these multiphase systems encompass solution casting, coating, spinning, 3D printing, thermomechanical processing. Strategies crosslinking alginate, plasticizing it, optimizing interactions polymers/fillers are outlined, bearing repercussions on resultant properties. This emphasizes structure–process–property relationships in highlights synergistic effects potential impediments property improvements. surveys prospective applications multiphasic spanning membrane separation, controlled release, wound healing, tissue engineering, food packaging, agricultural domains. Finally field, knowledge gaps have been identified future research directions suggested.
Language: Английский
Citations
31
European Polymer Journal, Journal Year: 2024, Volume and Issue: 213, P. 113078 - 113078
Published: May 16, 2024
Language: Английский
Citations
21
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 273, P. 132916 - 132916
Published: June 5, 2024
Language: Английский
Citations
20
Separation and Purification Technology, Journal Year: 2024, Volume and Issue: 353, P. 128265 - 128265
Published: June 6, 2024
Language: Английский
Citations
19
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 140958 - 140958
Published: Feb. 1, 2025
Language: Английский
Citations
5