Results in Chemistry, Journal Year: 2024, Volume and Issue: 11, P. 101854 - 101854
Published: Oct. 1, 2024
Language: Английский
Biomedicine & Pharmacotherapy, Journal Year: 2023, Volume and Issue: 169, P. 115891 - 115891
Published: Nov. 16, 2023
Lung cancer accounts for a relatively high proportion of malignant tumors. As the most prevalent type lung cancer, non-small cell (NSCLC) is characterized by morbidity and mortality. Presently, arsenal treatment strategies encompasses surgical resection, chemotherapy, targeted therapy radiotherapy. However, despite these options, prognosis remains distressingly poor with low 5-year survival rate. Therefore, it urgent to pursue paradigm shift in methodologies. In recent years, advent sophisticated biotechnologies interdisciplinary integration has provided innovative approaches cancer. This article reviews cutting-edge developments nano drug delivery system, molecular photothermal strategy, immunotherapy Overall, systematically summarizing critically analyzing latest progress current challenges we aim provide theoretical basis development novel drugs treatment, thus improve therapeutic outcomes patients.
Language: Английский
Citations
139
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 264, P. 130683 - 130683
Published: March 6, 2024
Language: Английский
Citations
30
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 273, P. 132916 - 132916
Published: June 5, 2024
Language: Английский
Citations
18
International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 253, P. 127278 - 127278
Published: Oct. 6, 2023
Language: Английский
Citations
34
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 135893 - 135893
Published: Sept. 1, 2024
Language: Английский
Citations
7
Artificial Cells Nanomedicine and Biotechnology, Journal Year: 2024, Volume and Issue: 52(1), P. 564 - 586
Published: Dec. 5, 2024
Cancer has a high rate of incidence and mortality throughout the world. Although several conventional approaches have been developed for treatment cancer, such as surgery, chemotherapy, radiotherapy thermal therapy, they remarkable disadvantages which result in inefficient cancer. For example, immunogenicity, prolonged treatment, non-specificity, metastasis cost are considered major drawbacks chemotherapy. Therefore, there is fundamental requirement development breakthrough technologies cancer suppression. Polysaccharide-based drug delivery systems (DDSs) most reliable carriers therapy. Polysaccharides, kind practical biomaterials, divided into types, including chitosan, alginates, dextran, hyaluronic acid, cyclodextrin, pectin, etc. Polysaccharides extracted from different natural resources (like herbal, marine, microorganisms, etc.). The potential features polysaccharides made them candidates therapeutics to sites; simple purification, ease modification functionalization, hydrophilicity, serum stability, appropriate loading capacity, biocompatibility, bioavailability, biodegradability stimuli-responsive sustained release manner considerable aspects these biopolymers. This review highlights applications polysaccharides-based DDSs pharmaceutical science
Language: Английский
Citations
7
Nanomaterials, Journal Year: 2024, Volume and Issue: 14(2), P. 186 - 186
Published: Jan. 13, 2024
Cancer is a severe disease that, in 2022, caused more than 9.89 million deaths worldwide. One worrisome type of cancer bone cancer, such as osteosarcoma and Ewing tumors, which occur frequently infants. This study shows an active interest the use graphene oxide its derivatives therapy against cancer. We present systematic review analyzing current state art related to GO treating osteosarcoma, through evaluating existing literature. In this sense, studies focused on GO-based nanomaterials for potential applications were reviewed, has revealed that there excellent trend toward nanomaterials, based their thermal anti-cancer activities, treatment various therapeutic approaches. However, research needed develop highly efficient localized therapies. It suggested, therefore, photodynamic therapy, photothermal nanocarriers should be considered non-invasive, specific, alternatives osteosarcoma. These options promising approaches enhance effectiveness while also seeking reduce side effects minimize damage surrounding healthy tissues. The bibliometric analysis photochemical treatments reduced from January 2004 December 2022 extracted 948 documents with search strategy, mainly papers, conference demonstrating high-impact field supported by need selective central countries leading are United States, Iran, Italy, Germany, China, South Korea, Australia, strong collaborations At same time, most-cited papers published journals impact factors 6.0 (2021), 290 citations. Additionally, most topic high factor journals, according performed, field.
Language: Английский
Citations
6
Frontiers in Bioengineering and Biotechnology, Journal Year: 2023, Volume and Issue: 11
Published: Nov. 1, 2023
Cancer presents a formidable threat to human health, with the majority of cases currently lacking complete cure. Frequently, chemotherapy drugs are required impede its progression. However, these frequently suffer from drawbacks such as poor selectivity, limited water solubility, low bioavailability, and propensity for causing organ toxicity. Consequently, concerted effort has been made seek improved drug delivery systems. Nano-drug systems based on biodegradable polyesters have emerged subject widespread interest in this pursuit. Extensive research demonstrated their potential offering high effective encapsulation, controlled release, minimal Notably, poly (ε-caprolactone) (PCL), (lactic-co-glycolic acid) (PLGA), polylactic acid (PLA) gained prominence most widely utilized options carriers nano system. This paper comprehensively reviews recent materials nano-carriers delivering chemotherapeutic drugs, summarizing latest advancements, acknowledging limitations, forecasting future directions.
Language: Английский
Citations
13
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 272, P. 132888 - 132888
Published: June 1, 2024
Language: Английский
Citations
4
Molecules, Journal Year: 2025, Volume and Issue: 30(2), P. 252 - 252
Published: Jan. 10, 2025
pH sensitivity of chitosan allows for precise phase transitions in acidic environments, controlling swelling and shrinking, making suitable drug delivery systems. are modulated by the presence cross-linkers functionalization chain. This review relays a summary tailoring to optimize release. The potential customize different environments therapeutic uses introduces opportunities encapsulation focus on improving sustained release specific tissues is an advanced interpretation, reflecting evolving role achieving targeted more efficient outcomes. describes strategies improve solubility stability ensure controlled encapsulated drugs. discussion optimizing factors like cross-linking density, particle size, deeper understanding how achieve effects. These represent refined approach designing chitosan-based systems, pushing boundaries technologies offering new avenues profiles.
Language: Английский
Citations
0