World Journal of Methodology,
Journal Year:
2024,
Volume and Issue:
14(3)
Published: June 25, 2024
The
lymphocyte
to
monocyte
ratio
(LMR)
is
considered
a
marker
of
systemic
inflammation
in
cardiovascular
disease
and
acts
as
predictor
mortality
coronary
artery
disease.
Immunity Inflammation and Disease,
Journal Year:
2024,
Volume and Issue:
12(9)
Published: Sept. 1, 2024
This
study
aimed
to
evaluate
six
novel
lymphocyte-based
inflammatory
markers
(neutrophil-lymphocyte
ratio,
monocyte-lymphocyte
platelet-lymphocyte
ratio
[PLR],
systemic
immune
inflammation
index
[SII],
response
index,
and
[SIIRI])
in
patients
with
newly
diagnosed
coronary
artery
disease
[CAD].
Journal of Diabetes Investigation,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 6, 2024
Previous
studies
have
shown
higher
cardiovascular
mortality
risk
with
monocyte-lymphocyte
ratio
levels
in
general
population.
However,
the
of
oxidative
stress
individuals
type
2
diabetes
are
than
those
population,
which
may
affect
link
between
monocyte-to-lymphocyte
and
disease
deaths.
And
association
people
still
be
unknown.
This
study
aimed
to
investigate
prognostic
significance
diabetes.
Journal of Clinical Medicine,
Journal Year:
2024,
Volume and Issue:
13(19), P. 5875 - 5875
Published: Oct. 2, 2024
Background:
The
pathophysiology
of
heart
failure
(HF)
with
preserved
ejection
fraction
(HFpEF)
is
suggested
to
be
influenced
by
inflammation.
Leukocyte
indices,
including
the
neutrophil–lymphocyte
ratio
(NLR),
monocyte–lymphocyte
(MLR),
and
pan-immune
inflammation
value
(PIV),
can
utilized
as
biomarkers
systemic
Their
prognostic
utility
yet
fully
understood.
Methods:
Between
December
2010
May
2023,
patients
presenting
a
tertiary
referral
center
for
HFpEF
were
included
into
prospective
registry.
association
NLR,
MLR,
PIV
composite
endpoint
all-cause
mortality
HF-related
hospitalization
was
tested
utilizing
Cox
regression
analysis.
Results:
In
total,
479
(median
74.3,
interquartile
range
(IQR):
69.22–78.3
years,
27.8%
male)
included.
Patients
observed
43
(IQR:
11–70)
months,
during
which
total
267
(55.7%)
met
primary
endpoint.
univariate
analysis,
an
above-the-median
NLR
implied
hazard
(HR)
1.76
(95%-confidence
interval
(CI):
1.38–2.24,
p
<
0.001),
MLR
1.46
(95%-CI:
1.14–1.86,
=
0.003),
1.67,
95%-CI:
1.30–2.13,
0.001)
After
adjustment
in
step-wise
model,
(HR:
1.81,
1.22–2.69,
1.57,
1.06–2.34,
0.026),
1.64,
1.10–2.46,
0.015)
remained
significantly
associated
combined
Conclusions:
are
simple
independently
outcomes
HFpEF.
