Polymer Bulletin,
Journal Year:
2024,
Volume and Issue:
81(15), P. 13975 - 13992
Published: June 24, 2024
Abstract
In
this
study,
the
lavender
essential
oil-incorporated
polylactic
acid
(PLA)
nanofibers
were
fabricated
by
electrospinning
technique
with
presence
of
kolliphor
as
a
nonionic
surfactant.
The
FTIR
spectra
supported
chemical
composition
fibers.
demonstrated
that
there
is
no
reaction
present
between
PLA
and
oil.
SEM
images
all
showed
bead-free
morphology.
ImageJ
results
average
diameter
oil-loaded
fibers
ranged
121.6
±
32
228.2
53
nm.
All
hydrophobic
satisfactory
thermal
properties.
Furthermore,
nanofibrous
mats
exhibited
good
antioxidant
activity.
concentration
oil
in
resulting
increased,
activity
also
increased.
According
to
can
be
considered
for
wide
range
potential
applications
such
active
packaging,
food
coating,
facial
masks,
wound
dressing.
Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
16(3)
Published: May 1, 2024
Abstract
The
shapes
of
micro‐
and
nano‐products
have
profound
influences
on
their
functional
performances,
which
has
not
received
sufficient
attention
during
the
past
several
decades.
Electrohydrodynamic
atomization
(EHDA)
techniques,
mainly
include
electrospinning
electrospraying,
are
facile
in
manipulate
products'
shapes.
In
this
review,
generated
using
EHDA
for
modifying
drug
release
profiles
reviewed.
These
linear
nanofibers,
round
micro‐/nano‐particles,
beads‐on‐a‐string
hybrids.
They
can
be
further
divided
into
different
kinds
sub‐shapes,
explored
providing
desired
pulsatile
release,
sustained
biphasic
delayed
pH‐sensitive
release.
Additionally,
resulted
from
organizations
electrospun
nanofibers
discussed
delivery,
inner
structures
considered
together
developing
novel
delivery
systems.
future,
related
shape–performance
relationships
at
nanoscale,
besides
size,
structure
structure–performance
relationships,
would
play
important
roles
promoting
developments
field.
This
article
is
categorized
under:
Therapeutic
Approaches
Drug
Discovery
>
Emerging
Technologies
Biomolecules,
Journal Year:
2024,
Volume and Issue:
14(7), P. 789 - 789
Published: July 3, 2024
Alginate
is
a
natural
polymer
with
good
biocompatible
properties
and
potential
polymeric
material
for
the
sustainable
development
replacement
of
petroleum
derivatives.
However,
non-spinnability
pure
alginate
solutions
has
hindered
expansion
applications.
With
continuous
electrospinning
technology,
synthetic
polymers,
such
as
PEO
PVA,
are
used
co-spinning
agents
to
increase
spinnability
alginate.
Moreover,
coaxial,
parallel
Janus,
tertiary
other
diverse
novel
electrospun
fiber
structures
prepared
by
multi-fluid
have
found
new
breakthrough
problem
poor
spinning
polymers.
Meanwhile,
effectively
achieve
multiple
release
modes
drugs.
The
powerful
combination
electrostatic
widely
in
many
biomedical
fields,
tissue
engineering,
regenerative
bioscaffolds,
drug
delivery,
research
fever
continues
climb.
This
particularly
true
controlled
delivery
aspect
review
provides
brief
overview
alginate,
introduces
advances
spinning,
highlights
progress
alginate-based
nanofibers
achieving
various
modes,
pulsed
release,
sustained
biphasic
responsive
targeted
release.
Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
16(2)
Published: March 1, 2024
Core-shell
structure
is
a
concentric
circle
found
in
nature.
The
rapid
development
of
electrospinning
technology
provides
more
approaches
for
the
production
core-shell
nanofibers.
nanoscale
effects
and
expansive
specific
surface
area
nanofibers
can
facilitate
dissolution
drugs.
By
employing
ingenious
structural
designs
judicious
polymer
selection,
specialized
nanofiber
drug
delivery
systems
be
prepared
to
achieve
controlled
release.
synergistic
combination
materials
exhibits
strong
strategy
enhancing
utilization
efficiency
customizing
release
profile
Consequently,
multi-chamber
hold
great
promise
highly
efficient
disease
treatment.
However,
little
attention
concentration
focused
on
effect
In
this
review,
we
introduced
different
fabrication
techniques
nanostructures,
including
advanced
technologies
functionalization.
Subsequently,
reviewed
behaviors
their
potential
needs
comprehensive
elucidation
based
electrospun
nanostructures
could
inspire
exploration
novel
systems.
Furthermore,
once
these
fibers
with
customizable
profiles
move
toward
industrial
mass
production,
they
will
potentially
promote
pharmacy
treatment
various
diseases.
This
article
categorized
under:
Therapeutic
Approaches
Drug
Discovery
>
Emerging
Technologies.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2024,
Volume and Issue:
12
Published: Feb. 5, 2024
Diabetic
wounds
are
a
significant
subset
of
chronic
characterized
by
elevated
levels
inflammatory
cytokines,
matrix
metalloproteinases
(MMPs),
and
reactive
oxygen
species
(ROS).
They
also
associated
with
impaired
angiogenesis,
persistent
infection,
high
likelihood
hospitalization,
leading
to
substantial
economic
burden
for
patients.
In
severe
cases,
amputation
or
even
mortality
may
occur.
foot
ulcers
(DFUs)
common
complication
diabetes,
up
25%
diabetic
patients
being
at
risk
developing
over
their
lifetime,
more
than
70%
ultimately
requiring
amputation.
Electrospun
scaffolds
exhibit
structural
similarity
the
extracellular
(ECM),
promoting
adhesion,
growth,
migration
fibroblasts,
thereby
facilitating
formation
new
skin
tissue
wound
site.
The
composition
size
electrospun
can
be
easily
adjusted,
enabling
controlled
drug
release
through
fiber
structure
modifications.
porous
nature
these
facilitates
gas
exchange
absorption
exudate.
Furthermore,
surface
readily
modified
impart
specific
functionalities,
making
electrospinning
nanofiber
highly
promising
treatment
wounds.
This
article
provides
concise
overview
healing
process
in
normal
pathological
mechanisms
underlying
wounds,
including
complications
such
as
ulcers.
It
explores
advantages
treatment.
Additionally,
it
summarizes
findings
from
various
studies
on
use
different
types
reviews
methods
loading
onto
scaffolds.
These
advancements
broaden
horizon
effectively
treating
Polymers,
Journal Year:
2024,
Volume and Issue:
16(4), P. 504 - 504
Published: Feb. 12, 2024
In
the
21st
century,
chemotherapy
stands
as
a
primary
treatment
method
for
prevalent
diseases,
yet
drug
resistance
remains
pressing
challenge.
Utilizing
electrospinning
to
support
drugs
offers
sustained
and
controlled
release
methods
in
contrast
oral
implantable
delivery
modes,
which
enable
localized
of
distinct
tumor
types.
Moreover,
core–sheath
structure
bears
advantages
dual-drug
loading:
core
sheath
layers
can
carry
different
drugs,
facilitating
collaborative
counter
resistance.
This
approach
minimizes
patient
discomfort
associated
with
multiple-drug
administration.
Electrospun
fibers
not
only
transport
but
also
integrate
metal
particles
targeted
compounds,
enabling
combinations
magnetic
heat
therapies
comprehensive
cancer
treatment.
review
delves
into
preparation
techniques
tailored
various
cancers,
foreseeing
their
promising
roles
