Effects of mobilization or manipulation of the thoracic spine on autonomic nervous system markers in symptomatic and asymptomatic participants – a systematic review and meta-analysis DOI
Lars Kai Hansen,

Hartmut Goebel,

Larissa Pagels

et al.

Journal of Manual & Manipulative Therapy, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 24

Published: April 15, 2025

To identify the effects of thoracic mobilization/manipulation on autonomic nervous system responses. Four electronic databases were searched for controlled trials published before February 2024. Studies spine included evaluating (ANS). Risk bias was assessed by two independent assessors using Cochrane risk-of-bias tool 2, RoB-2 crossover studies or ROBINS-I tool. Meta-analyses random-effects models present overall combined mean effects. 2139 articles identified, 20 (863 participants) in qualitative data analysis and 15 meta-analyses. had a high risk one more domains. indicated no statistically significant effect mobilization manipulation markers ANS. The ratio low-frequency-to-high-frequency power did not significantly decrease after compared to any type control intervention (-0.28; 95% CI -0.59 0.04; p=0.09). Skin conductance root square successive RR interval differences as well LFab (ms^2; absolute low-frequency band) increase mobilization/manipulation. Subgroup sensitivity-analyses Methodological limitations heterogeneity (I2=0-94%) reported outcomes, reduce level evidence. Future with rigorous methodological approach symptomatic participants longer follow-ups are warranted. No ANS found. direction changes towards increased decreased sympathetic parasympathetic activity ambiguous.

Language: Английский

Integration of wearable electronics and heart rate variability for human physical and mental well-being assessment DOI
Feifei Yin, Jian Chen, Hao Xue

et al.

Journal of Semiconductors, Journal Year: 2025, Volume and Issue: 46(1), P. 011603 - 011603

Published: Jan. 1, 2025

Abstract Heart rate variability (HRV) that can reflect the dynamic balance between sympathetic nervous and parasympathetic of human autonomic system (ANS) has attracted considerable attention. However, traditional electrocardiogram (ECG) devices for HRV analysis are bulky, hard wires needed to attach measuring electrodes chest, resulting in poor wearable experience during long-term measurement. Compared with that, electronics enabling continuously cardiac signals monitoring assessment provide a desirable promising approach helping subjects determine sleeping issues, cardiovascular diseases, or other threats physical mental well-being. Until now, significant progress advances have been achieved applications predicting In this review, latest integration as well practical health included. The commonly used methods physiological briefly summarized. Furthermore, we highlighted research on concerning diverse such stress estimation, drowsiness detection, etc. Lastly, current limitations integrated concluded, possible solutions direction outlined.

Language: Английский

Citations

3

The effects of ketogenic metabolic therapy on mental health and metabolic outcomes in schizophrenia and bipolar disorder: a randomized controlled clinical trial protocol DOI Creative Commons
Calogero Longhitano,

Sabine Finlay,

Isabella Peachey

et al.

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Aug. 21, 2024

Background Schizophrenia, schizoaffective disorder, and bipolar affective disorder are debilitating psychiatric conditions characterized by a chronic pattern of emotional, behavioral, cognitive disturbances. Shared psychopathology includes the pre-eminence altered states, disorders thoughts, behavioral control. Additionally, those share epidemiological traits, including significant cardiovascular, metabolic, infectious, respiratory co-morbidities, resulting in reduced life expectancy up to 25 years. Nutritional ketosis has been successfully used treat range neurological preclinical data have convincingly shown potential for its use animal models psychotic disorders. More recent from open clinical trials pointed toward dramatic reduction psychotic, affective, metabolic symptoms both schizophrenia disorder. Objectives investigate effects nutritional via modified ketogenic diet (MKD) over 14 weeks stable community patients with or schizophrenia. Design A randomized placebo-controlled trial 100 non-hospitalized adult participants diagnosis who capable consenting willing change their diets. Intervention Dietitian-led medically supervised compared following Australian Guide Healthy Eating weeks. Outcomes The primary outcomes include measures, reported as symptom improvement functional changes Positive Negative Symptoms Scale (PANSS), Young Mania Rating (YMS), Beck Depression Inventory (BDI), WHO Disability Schedule, Affect Lability Cambridge Cognitive Battery. secondary body weight, blood pressure, liver kidney function tests, lipid profiles, markers insulin resistance. Ketone glucose levels will be study correlation between outcomes. Optional hair cortisol analysis assess long-term stress variations fecal microbiome composition. Autonomic nervous system activity measured wearable devices (OURA ring EMBRACE wristband) form skin conductance, oximetry, continuous pulse monitoring, rate, movement tracking, sleep quality. Based on encouraging results established research, other neurodevelopment disorders, schizophrenia, we predict that therapy well tolerated result improved global measures social functioning. We additionally may exist level achieved cognitive, intervention group.

Language: Английский

Citations

10

Heart rate variability, a potential assessment tool for identifying anxiety, depression, and sleep disorders in elderly individuals DOI Creative Commons

Wenna Liu,

Shutong Wang,

Hanyang Gu

et al.

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 16

Published: Jan. 23, 2025

Introduction This study investigates how anxiety, depression, and sleep disorders impact heart rate variability (HRV) in the elderly, exploring clinical implications of HRV changes. Methods We examined 355 patients (163 men, 192 women) at Xijing Hospital from July 2021 to December 2022 during health check-ups. Demographics were recorded, emotional status was assessed using Hamilton Anxiety Scale (HAMA) Depression (HAMD). The Pittsburgh Sleep Quality (PSQI) evaluated quality. Patients categorized into groups A-G based on presence states disorders. indices—SDNN, SDANN, RMSSD, PNN50, LF/HF, LF, HF—were analyzed ANOVA multivariate logistic regression. Results No statistically significant differences observed demographic, clinical, lifestyle factors across eight groups. Variables included age, sex, body mass index (BMI), fasting blood glucose, glycated hemoglobin (HbA1c), lipids, pressure, rate, histories smoking alcohol consumption. Additionally, hypertension, diabetes, coronary disease, marital status, income, education level evaluated, with all showing equivalence ( P > 0.05). Significant indices groups, particularly group G (patients depression disorders), which showed decreased parameters except H (control group), increased parameters, also LF/HF < 0.01). an independent risk factor for reduced SDNN, LF ≤ 0.01), ratio linked HF independently predicted PNN50 SDANN Conclusion individuals varying exhibited degrees decrease. Anxiety, presented a superimposed effect HRV. are great reference value diagnosis For elderly experiencing cognitive impairment, is anticipated serve as convenient effective tool assessing mood

Language: Английский

Citations

1

Beyond Limits: The Fusion of Nature and Technology in Achieving Optimal Health—The Truth of Biohacking DOI

Dorothea Portius

Published: Jan. 1, 2025

Language: Английский

Citations

1

Behavioral and psychophysiological responses of initial pilots in collaboration with an experienced but risky captain: A flight-simulation study based on the social facilitation DOI
Shan Gao, Yu Bai, Ruiyuan Hong

et al.

Safety Science, Journal Year: 2025, Volume and Issue: 187, P. 106858 - 106858

Published: March 15, 2025

Language: Английский

Citations

1

POST-TRAUMATIC STRESS DISORDER, INSOMNIA, HEART RATE VARIABILITY AND METABOLIC SYNDROME (NARRATIVE REVIEW) DOI Creative Commons
A.A. Serhiyenko, Myroslav Baitsar,

V.B. Sehin

et al.

Proceedings of the Shevchenko Scientific Society Medical Sciences, Journal Year: 2024, Volume and Issue: 73(1)

Published: June 28, 2024

This narrative review was aimed to analyze the scientific data about association of post-traumatic stress disorder, insomnia, obstructive sleep apnea syndrome, dyssomnias, heart rate variability, metabolic type 2 diabetes mellitus, and cardiovascular autonomic neuropathy, along with potential pathophysiological mechanisms underlying these associations. The results experimental, cohort, prospective, randomized clinical studies provide evidence common pathogenetic pathways contributing their development. Searches were conducted in Scopus, Science Direct (from Elsevier), EBSCO, PubMed databases, including Medline databases. Additionally, a manual search publication bibliographies undertaken uncover research outcomes not accessible through online searches.

Language: Английский

Citations

6

Heart–Brain Axis: A Narrative Review of the Interaction between Depression and Arrhythmia DOI Creative Commons

Shuping Fang,

Wei Zhang

Biomedicines, Journal Year: 2024, Volume and Issue: 12(8), P. 1719 - 1719

Published: Aug. 1, 2024

Arrhythmias and depression are recognized as diseases of the heart brain, respectively, both major health threats that often co-occur with a bidirectional causal relationship. The autonomic nervous system (ANS) serves crucial component heart–brain axis (HBA) pathway interoception. Cardiac activity can influence emotional states through ascending interoceptive pathways, while psychological stress precipitate arrhythmias via ANS. However, HBA interoception frameworks considered overly broad, precise mechanisms underlying relationship between remain unclear. This narrative review aims to synthesize existing literature, focusing on pathological ANS in arrhythmia integrating other potential detail interactions. In communication we emphasize considering various internal factors such genes, personality traits, stress, endocrine system, inflammation, 5-hydroxytryptamine, behavioral factors. Current research employs multidisciplinary knowledge elucidate relationships, deeper understanding these interactions help optimize clinical treatment strategies. From broader perspective, this study emphasizes importance body complex, interconnected rather than treating organs isolation. Investigating enhance our disease pathogenesis advances medical science, ultimately improving human quality life.

Language: Английский

Citations

6

Cardiorespiratory fitness, perceived fitness and autonomic function in in-patients with different depression severity compared with healthy controls DOI Creative Commons
Jan-Niklas Kreppke, C. Robyn, Johannes Beck

et al.

Journal of Psychiatric Research, Journal Year: 2024, Volume and Issue: 175, P. 437 - 445

Published: May 21, 2024

Over 300 million individuals worldwide suffer from major depressive disorder (MDD). Individuals with MDD are less physically active than healthy people which results in lower cardiorespiratory fitness (CRF) and favorable perceived compared controls. Additionally, may show autonomic system dysfunction. The purpose of the present study was to evaluate CRF, function in-patients different severity We used data 212 (age: 40.7 ± 12.6 y, 53% female) 141 controls 36.7 12.7 58% female). assessed CRF Åstrand-Rhyming test, self-reported by heart rate variability (HRV). In specific, we resting rate, time- frequency-based parameters for HRV. In-patients completed Beck Depression Inventory-II (BDI-II) self-assess subjectively rated depression. Based on these scores, participants were grouped into mild, moderate severe MDD. main finding an inverse association between depression as well Resting elevated increasing severity. time-based but not showed pattern suggests that among disorder, those particularly high self-assessed scores a partial dysfunction To counteract conditions, physical activity interventions be effective.

Language: Английский

Citations

5

Cardiovascular toxic effects of nanoparticles and corresponding molecular mechanisms DOI

Chunfeng Huang,

Xuting Liu,

Qingchun Wu

et al.

Environmental Pollution, Journal Year: 2024, Volume and Issue: 356, P. 124360 - 124360

Published: June 12, 2024

Language: Английский

Citations

4

Emotion contagion and physiological synchrony: The more intimate relationships, the more contagion of positive emotions DOI

Daichun Lin,

Tongtong Zhu,

Yanmei Wang

et al.

Physiology & Behavior, Journal Year: 2023, Volume and Issue: 275, P. 114434 - 114434

Published: Dec. 11, 2023

Language: Английский

Citations

11