Nanomaterials,
Journal Year:
2025,
Volume and Issue:
15(6), P. 441 - 441
Published: March 14, 2025
A
stabilized
biochar
(BC)–nano-scale
zero-valent
iron
(nZVI)
composite
(BC-nZVI@Cell-g-PAA)
was
prepared
using
cellulose-grafted
polyacrylic
acid
(Cell-g-PAA)
as
the
raw
material
through
in
situ
polymerization
and
liquid-phase
reduction
methods
for
remediation
of
hexavalent
chromium
(Cr(VI))-contaminated
water.
BC-nZVI@Cell-g-PAA
characterized
by
XRD,
FT-IR,
SEM,
BET,
TEM,
XPS.
According
to
batch
experiments,
under
optimized
conditions
(Cr(VI)
concentration
50
mg/L,
pH
=
3,
dosage
2
g/L),
achieved
maximum
Cr(VI)
removal
efficiency
(99.69%)
within
120
min.
Notably,
BC,
a
carrier,
high
dispersion
nZVI
its
porous
structure,
effectively
preventing
particle
agglomeration
improving
reaction
activity.
Simultaneously,
functional
groups
on
surface
Cell-g-PAA
provided
excellent
protection
nZVI,
significantly
suppressing
oxidative
deactivation.
Furthermore,
reduced
insoluble
trivalent
chromium(Cr(III))
species
them
immobilization.
The
synergistic
effects
physical
adsorption
chemical
greatly
contributed
Cr(VI).
Remarkably,
exhibited
reusability
with
62.4%
after
five
cycles,
demonstrating
potential
promising
remediating
Cr(VI)-contaminated
In
conclusion,
not
only
demonstrated
remarkable
but
also
showcased
practical
applications
environmental
remediation,
evidenced
sustained
performance
over
multiple
reuse
cycles.
Moreover,
Cr(VI),
toxic
carcinogenic
substance,
poses
significant
risks
aquatic
ecosystems
human
health,
underscoring
importance
developing
effective
from
contaminated
Environmental Toxicology,
Journal Year:
2022,
Volume and Issue:
37(8), P. 2033 - 2043
Published: April 21, 2022
Deltamethrin
(DLM)
is
a
widely
used
and
highly
effective
insecticide.
DLM
exposure
harmful
to
animal
human.
Quail,
as
bird
model,
has
been
in
the
field
of
toxicology.
However,
there
little
information
available
literature
about
quail
cerebrum
damage
caused
by
DLM.
Here,
we
investigated
effect
on
neurons.
Four
groups
healthy
quails
were
assigned
(10
each
group),
respectively
given
0,
15,
30,
45
mg/kg
gavage
for
12
weeks.
Through
measurements
cerebrum,
it
was
found
that
induced
obvious
histological
changes,
oxidative
stress,
neurons
apoptosis.
To
further
explore
possible
molecular
mechanisms,
performed
real-time
quantitative
PCR
detect
expression
endoplasmic
reticulum
(ER)
stress-related
mRNA
such
glucose
regulated
protein
78
kD,
activating
transcription
factor
6,
inositol
requiring
enzyme,
kinase
RNA
(PKR)-like
ER
kinase.
In
addition,
detected
ATP
content
evaluate
functional
status
mitochondria.
The
study
showed
significantly
increased
decreased
tissues.
These
results
suggest
chronic
induces
apoptosis
via
promoting
stress
mitochondrial
dysfunction.
Furthermore,
our
provide
novel
explanation
DLM-induced
avian
Oxidative Medicine and Cellular Longevity,
Journal Year:
2022,
Volume and Issue:
2022, P. 1 - 23
Published: April 16, 2022
Although
massive
hepatocyte
cell
death
and
oxidative
stress
constitute
major
events
of
acute-on-chronic
liver
failure
(ACLF),
the
relationship
ferroptosis
with
ACLF
has
yet
to
be
explored.
Nuclear
factor
erythroid
2-related
2
(Nrf2)
is
a
key
regulator
ferroptosis.
However,
if
Nrf2
modulates
through
remains
unknown.
Here,
tissues
patients
were
collected
murine
models
using
carbon
tetrachloride,
D-galactosamine,
lipopolysaccharide
as
well
an
H2O2-induced
injury
model
established.
Upon
ACLF,
livers
exhibited
features
ferroptosis,
including
lipid
peroxidation
(increase
in
malondialdehyde
whereas
decrease
glutathione
nicotinamide
adenine
dinucleotide
phosphate),
increased
mRNA
expression
prostaglandin-endoperoxide
synthase-2
(PTGS2).
Ferroptosis
inducer
RSL-3
treatment
aggravated
damage,
while
inhibitor
Ferrostatin-1
administration
alleviated
severity,
manifesting
improved
histopathological
lesions
reduced
serum
ALT
AST.
Compared
normal
tissue,
was
upregulated
models.
Pharmacological
activation
(Bardoxolone
Methyl)
attenuated
prevented
peroxidation,
PTGS2
expression,
ferroptosis-specific
mitochondrial
morphology
vivo.
In
contrast,
ML385
exacerbated
injury.
Collectively,
plays
protective
role
progression
repressing
which
provides
promising
therapeutic
cues
for
ACLF.
Journal of Agricultural and Food Chemistry,
Journal Year:
2024,
Volume and Issue:
72(28), P. 15985 - 15997
Published: July 3, 2024
Liver
disease
has
become
an
important
risk
factor
for
global
health.
Resveratrol
(Res)
is
a
natural
polyphenol
which
widely
found
in
foods
and
variety
of
biological
activities.
This
study
investigated
the
role
microbiota-gut-liver
axis
Res
relieving
liver
fibrosis
induced
by
inorganic
mercury
exposure.
Twenty-eight
mice
were
divided
into
four
groups
(n
=
7)
treated
with
mercuric
chloride
and/or
24
weeks,
respectively.
The
results
showed
that
mitigated
ileum
injury
restrained
LPS
alcohol
entering
body
circulation.
Network
pharmacological
molecular
analyses
alleviated
oxidative
stress,
metabolism
disorders,
inflammation,
hepatic
stellate
cell
activation
liver.
In
conclusion,
alleviates
via
activating
Sirt1/PGC-1α
signaling
pathway
regulating
microbial-gut-liver
axis,
particularly,
increasing
relative
enrichment
Bifidobacterium
intestinal
tract.
Bioengineered,
Journal Year:
2021,
Volume and Issue:
12(2), P. 9993 - 10006
Published: Oct. 21, 2021
Curcumin
suppressed
ultraviolet
(UV)
induced
skin
carcinogenesis
and
activated
the
nuclear
factor
erythroid
2-related
2
(Nrf2)
pathway.
However,
whether
curcumin
protects
injury
caused
by
UV
is
still
unknown.
A
vitro
model
was
established
effects
on
Hacat
cells
were
detected.
Nrf2
knocked
down
in
to
verify
role
protective
effect
of
curcumin.
Results
indicated
that
(UVA)
(or
B
(UVB))
irradiation
would
lead
decreased
cell
proliferation,
increased
apoptosis,
catalase,
heme
oxygenase
1,
superoxide
dismutase
expression,
levels
protein
carbonylation
malondialdehyde
(p
<
0.05).
These
adverse
events
could
be
reversed
adding
5-μM
Meanwhile,
we
found
application
effectively
accumulation
cells.
While
knockdown
cells,
against
UVA
UVB)
attenuated.
Conclusively,
exposure-induced
photo-damage
regulating
expression.
