Risk and performance disclosure during the Covid-19 pandemic: does ownership structure matter? DOI
Rihab Grassa,

Mohammad Alhashmi,

Rashed Rafeea

et al.

Journal of financial reporting & accounting, Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 26, 2023

Purpose This paper aims to investigate whether risk-related information is associated with a higher level of performance disclosure (PerfD) in the annual reports during Covid-19 pandemic. Additionally, this assesses if ownership structure plays moderating effect on relationship between RD and PerfD. Design/methodology/approach A content analysis technique measure risk PerfD for 72 listed firms Abu Dhabi stock exchange Dubai financial market period 2019–2021. Findings The authors find significant correlation Indeed, managers use send signal about their abilities skills managing high-risk situations by disclosing more performance-related accompanying any communicated related information. Besides, our results report that before pandemic, only government had However, foreign also played an important role improve firm transparency. In addition, Big 4 audit have effective quality control, auditors would play improving disclosure. leveraged high may critical mitigating debtholders’ concerns firm’ ability manage pandemic situation generate enough cash flows future pay debts. Originality/value paper’s findings are highly relevant reporting’ users, mainly shareholders, as they will be aware management behaviors crisis how engaged useful regulators reinforce maintain good reporting, especially circumstances. benefit from through optimization (dispersed ownership), which helps promote transparency

Language: Английский

Autoimmune and autoinflammatory conditions after COVID-19 vaccination. New case reports and updated literature review DOI
Yhojan Rodríguez, Manuel Rojas, Santiago Beltrán

et al.

Journal of Autoimmunity, Journal Year: 2022, Volume and Issue: 132, P. 102898 - 102898

Published: Aug. 24, 2022

Language: Английский

Citations

79
SARS-CoV-2 vaccine may trigger thyroid autoimmunity: real-life experience and review of the literature DOI Open Access
Rosaria Maddalena Ruggeri,

L. Giovanellla,

Alfredo Campennì

et al.

Journal of Endocrinological Investigation, Journal Year: 2022, Volume and Issue: 45(12), P. 2283 - 2289

Published: July 12, 2022

Language: Английский

Citations

36
COVID-19 vaccination and thyroiditis DOI Open Access
Süleyman Nahit Şendur, Seda Hanife Oğuz, Uğur Ünlütürk

et al.

Best Practice & Research Clinical Endocrinology & Metabolism, Journal Year: 2023, Volume and Issue: 37(4), P. 101759 - 101759

Published: March 3, 2023

Language: Английский

Citations

18
COVID‐19‐induced autoimmune thyroiditis: Exploring molecular mechanisms DOI
Bita Mohammadi, Kamal Dua,

Mohammadreza Saghafi

et al.

Journal of Medical Virology, Journal Year: 2023, Volume and Issue: 95(8)

Published: July 29, 2023

Abstract Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) damages multiple organs, including the thyroid, by direct invasion and cell entry via angiotensin‐converting enzyme 2 or indirectly promoting excessive inflammation in body. The immune system is a critical factor antiviral immunity disease progression. In context of SARS‐CoV‐2 infection, may become overly activated, resulting shift from regulatory to effector responses, which subsequently promote development progression autoimmune diseases. incidence thyroid diseases, such as subacute thyroiditis, Graves' disease, Hashimoto's increases individuals with COVID‐19 infection. This phenomenon be attributed aberrant responses T‐cell subtypes, presence autoantibodies, impaired function, production inflammatory cytokines, namely interleukin (IL)‐6, IL‐1β, interferon‐γ, tumor necrosis factor‐α. Therefore, insights into involved according can help identify potential therapeutic approaches guide effective interventions alleviate patients' symptoms.

Language: Английский

Citations

15
Endocrine system after 2 years of COVID-19 vaccines: A narrative review of the literature DOI Creative Commons
Letizia Chiara Pezzaioli, Elisa Gatta, Francesca Bambini

et al.

Frontiers in Endocrinology, Journal Year: 2022, Volume and Issue: 13

Published: Nov. 10, 2022

Purpose The purpose of this study was to describe the current knowledge on potential endocrine adverse effects post-COVID-19 vaccines. Methods A PubMed/MEDLINE, Web Science, and Scopus research performed. Case reports, case series, original studies, reviews written in English published online up 31 July 2022 were selected reviewed. final reference list defined based relevance each paper scope review. Results available data showed that side are generally rare with favorable outcome, being thyroid disorders most common. Conversely, type 1 diabetes mellitus rare; adrenal pituitary events even anecdotal. Finally, clinical studies suggest no impact female reproductive system male couple fertility. Conclusion Overall, these show that, after 2 years COVID-19 vaccines, is not heavily threatened.

Language: Английский

Citations

22
Assessing the Causal Association Between COVID-19 and Graves Disease: Mendelian Randomization Study DOI Creative Commons

Hui Nian,

Yu Bai,

Hua Yu

et al.

JMIR Formative Research, Journal Year: 2025, Volume and Issue: 9, P. e66003 - e66003

Published: April 8, 2025

Abstract Background Graves disease (GD) is an autoimmune thyroid disorder characterized by hyperthyroidism and autoantibodies. The COVID-19 pandemic has raised questions about its potential relationship with diseases like GD. Objective This study aims to investigate the causal association between GD through Mendelian randomization (MR) analysis assess impact of on Methods We conducted MR using extensive genome-wide data for susceptibility severity. used stringent single nucleotide polymorphism selection criteria various methodologies, including inverse-variance weighting, MR-Egger, weighted median analyses, relationships. also tests directional pleiotropy heterogeneity, as well sensitivity analyses. Results analysis, based largest available dataset date, did not provide evidence supporting a (odds ratio [OR] 0.989, 95% CI 0.405‐2.851; P =.93), hospitalization (OR 0.974, 0.852‐1.113; =.70), severity 0.979, 0.890‐1.077; =.66), Tests supported these findings. Conclusions comprehensive does sufficient support onset or exacerbation These results contribute better understanding diseases, alleviating concerns surge in due pandemic. Further research warranted explore this complex thoroughly.

Language: Английский

Citations

0
Graves‘ disease following vaccination against SARS-CoV-2: A systematic review of the reported cases DOI Creative Commons
Konstantinos Katsikas Triantafyllidis, Panagiotis Giannos,

Dimitra Stathi

et al.

Frontiers in Endocrinology, Journal Year: 2022, Volume and Issue: 13

Published: Sept. 27, 2022

The newly developed COVID-19 vaccines have established a safe profile, yet some individuals experience wide range of adverse events. Recently, thyroid dysfunction, including Graves' disease, has been observed after administration different vaccines, although causality remains matter debate. aim this systematic review was to examine the available literature and provide an overview reported cases disease following vaccination. We identified 21 eligible articles which included 57 patients with Fourteen participants were males (25%, 14/57) 43 (75%, 44/57) females mean age 44.3 years. most common presenting symptom palpitations (63%, 27/43) followed by weight loss (35%, 15/43). majority received thionamides (47%, 25/53). clinical status treatment provided for 37 it improved in them (84%, 31/37). is possibly condition clinicians may expect encounter receiving vaccines. While above event rare, considering scarcity data scientific literature, not confirmed, increased awareness early recognition disorder are important optimal management these patients.

Language: Английский

Citations

18
Influence of COVID-19 vaccines on endocrine system DOI Open Access
Ying Zhao, Xiaohong Wu

Endocrine, Journal Year: 2022, Volume and Issue: 78(2), P. 241 - 246

Published: June 25, 2022

Language: Английский

Citations

17
Graves’ orbitopathy post-SARS-CoV-2 vaccines: report on six patients DOI Open Access

Juliette Abeillon-du Payrat,

Solange Grunenwald,

E. Gall

et al.

Journal of Endocrinological Investigation, Journal Year: 2022, Volume and Issue: 46(3), P. 617 - 627

Published: Nov. 15, 2022

Language: Английский

Citations

16
Graves’ disease after exposure to the SARS-CoV-2 vaccine: a case report and review of the literature DOI Creative Commons
Kai Takedani, Masakazu Notsu,

Naoto Ishiai

et al.

BMC Endocrine Disorders, Journal Year: 2023, Volume and Issue: 23(1)

Published: June 15, 2023

Abstract Background Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) is characterized immune system dysregulation after exposure to adjuvants, such as aluminum. Although cases of autoimmune thyroid diseases caused ASIA have been reported, Graves' disease one the rarer diseases. There are some reports that vaccines against severe acute respiratory coronavirus 2 (SARS-CoV-2) cause ASIA. Here, we describe a case Graves’ following SARS-CoV-2 vaccination and review literature. Case presentation A 41-year-old woman was admitted our hospital because palpitations fatigue. Two weeks receiving second vaccine (BNT162b2, Coronavirus Modified Uridine messenger RNA (mRNA) Vaccine, Pfizer), she developed fatigue gradually worsened. On admission, exhibited thyrotoxicosis (thyroid-stimulating hormone (TSH) < 0.01 mIU/L (0.08–0.54), free triiodothyronine (FT3) 33.2 pmol/L (3.8–6.3), thyroxine (FT4) 72.1 (11.6–19.3)) associated with atrial fibrillation. TSH receptor antibody (TRAb) positive (TRAb 5.0 IU/L (< 2.0)), 99m Tc scintigraphy showed diffuse uptake in gland, suggesting this disease. Thiamazole prescribed correct her condition, soon treatment initiated, symptoms levels were significantly reduced. Conclusions This report reinforces potential correlation between affecting mRNA vaccines. The clinical course suggests it essential consider possibility developing ASIA, disease, vaccine.

Language: Английский

Citations

10