Ceramics International, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 1, 2025
Language: Английский
Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 95, P. 105601 - 105601
Published: March 18, 2024
Language: Английский
Citations
28
International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(14), P. 7810 - 7810
Published: July 17, 2024
Nowadays, as a result of the frequent occurrence accidental injuries and traumas such bone damage, number people causing or fractures is increasing around world. The design fabrication ideal tissue engineering (BTE) materials have become research hotspot in scientific community, thus provide novel path for treatment diseases. Among used to construct scaffolds BTE, including metals, bioceramics, bioglasses, biomacromolecules, synthetic organic polymers, etc., natural biopolymers more advantages against them because they can interact with cells well, polymers be widely studied applied field BTE. In particular, alginate has excellent biocompatibility, good biodegradability, non-immunogenicity, non-toxicity, wide sources, low price, easy gelation, enabling itself biomaterial. However, pure hydrogel BTE scaffold material still many shortcomings, insufficient mechanical properties, disintegration physiological environments, lack cell-specific recognition sites, which severely limits its clinical application order overcome defects single hydrogels, researchers prepared composite hydrogels by adding one matrix certain proportion improve their bioapplicability. For this reason, review will introduce detail methods constructing alginate/polymer alginate/bioprotein polypeptide alginate/bioceramic alginate/nanoclay well biological trends materials, look forward future direction. These exhibit both unexceptionable biochemical high value repair regeneration, providing theoretical basis development sustainable alginate-based functional biomedical materials.
Language: Английский
Citations
14
Biomaterials Advances, Journal Year: 2024, Volume and Issue: 159, P. 213828 - 213828
Published: March 11, 2024
Language: Английский
Citations
13
Biomimetics, Journal Year: 2024, Volume and Issue: 9(7), P. 409 - 409
Published: July 5, 2024
The aim of this study is to provide an overview the current state-of-the-art in fabrication bioceramic scaffolds for bone tissue engineering, with emphasis on use three-dimensional (3D) technologies coupled generative design principles. field modern medicine has witnessed remarkable advancements and continuous innovation recent decades, driven by a relentless desire improve patient outcomes quality life. Central progress which holds immense promise regenerative applications. Scaffolds are integral engineering serve as 3D frameworks that support cell attachment, proliferation, differentiation. A wide array materials been explored scaffolds, including bioceramics (i.e., hydroxyapatite, beta-tricalcium phosphate, bioglasses) bioceramic–polymer composites, each offering unique properties functionalities tailored specific Several methods, such thermal-induced phase separation, electrospinning, freeze-drying, gas foaming, particle leaching/solvent casting, fused deposition modeling, printing, stereolithography selective laser sintering, will be introduced thoroughly analyzed discussed from point view their characteristics, have proven invaluable obtaining scaffolds. Moreover, highlighting important role scaffold optimization, review seeks pave way development innovative strategies personalized solutions address significant gaps literature, mainly related complex defects engineering.
Language: Английский
Citations
13
ACS Applied Bio Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
The resection of bone tumors results in large defects with some residual tumor cells, and the treatment this type defect area often faces a dilemma, namely, trade-off between repair antitumor after tumors. In order to promote local repair, at same time inhibit recurrence by continuous controlled drug administration, we developed multifunctional NIR-responsive scaffold, whose main components are polylactic acid MXene, loaded PLGA/DOX microspheres, hope that scaffold can take into account both bidirectional modulation effect NIR. showed 1% MXene content had relatively good performance photothermal therapy (PT) other aspects, it could be smoothly increased 50 °C within 2 min under NIR illumination, release microspheres was 10% illumination compared body temperature. vivo experiments animals effectively limited situ cells lung metastasis able osteogenic differentiation irradiation. Therefore, not only control drugs but also enhance through PT formation, which provides application solution for integrated surgery.
Language: Английский
Citations
1
Ceramics International, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Language: Английский
Citations
1
ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: 17(2), P. 2791 - 2813
Published: Jan. 6, 2025
Transplantation of bone implants is currently recognized as one the most effective means treating defects. Biobased and biodegradable polyester composites combine good mechanical degradable properties polyester, thereby providing an alternative for implant materials. Bone tissue engineering (BTE) accelerates defect repair by simulating microenvironment. Composite scaffolds support formation further accelerate process repair. The introduction 3D printing technology enables preparation to be more precise, reproducible, flexible, which a very promising development. This review presents physical BTE summarizes strategies adopted domestic international scholars improve based on biobased polyester/ceramic in recent years. In addition, future development prospects field challenges expanding production clinical applications are presented.
Language: Английский
Citations
1
Regenerative Engineering and Translational Medicine, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 17, 2025
Language: Английский
Citations
1
Coatings, Journal Year: 2024, Volume and Issue: 14(7), P. 848 - 848
Published: July 6, 2024
Metal and metal oxide nanoparticles are gaining traction in inorganic catalysis photocatalysis, driving the development of eco-friendly methods. This study introduces an cost-effective approach for synthesizing Al2O3 (NPs) using extracts derived from leaves Calligonum comosum L. The primary objective this investigation is to assess photocatalytic efficacy synthesized catalyst addressing organic pollutants. NPs exhibit a spherical morphology with crystalline arrangements, as evidenced by average crystallite size 25.1 nm XRD analysis. band gap energy determined be 2.86 eV. In terms mechanical properties, show significant potential enhancing both flexural compressive thereby making them viable choice improving performance composites. Notably, Young’s modulus hybrid composite (comprising plant material NPs) exhibits remarkable increase 34.4% flexion 78.3% compression compared alone. catalytic evaluated methylene blue (MB) cationic dye Rose Bengal (RB) anionic dye. Impressively, demonstrate degradation efficiencies 98.2% MB 90.5% RB. processes occur under solar light irradiation, contact time 120 m, maintained pH 7, temperature 25 °C. found that promising, cost-effective, environmentally friendly option water treatment.
Language: Английский
Citations
7
Acta Biomaterialia, Journal Year: 2024, Volume and Issue: 185, P. 111 - 125
Published: July 11, 2024
Language: Английский
Citations
6