A Comparative Genomic and Phylogenetic Investigation of the Xenobiotic Metabolism Enzymes of Cytochrome P450 in Elephants Shows Loss in CYP2E and CYP4A DOI Creative Commons
Kanami Watanabe, Mitsuki Kondo, Yoshinori Ikenaka

et al.

Animals, Journal Year: 2023, Volume and Issue: 13(12), P. 1939 - 1939

Published: June 9, 2023

Cytochrome P450 is an important enzyme that metabolizes a variety of chemicals, including exogenous substances, such as drugs and environmental endogenous steroids, fatty acids, cholesterol. Some CYPs show interspecific differences in terms genetic variation. As little known about the mechanisms elephant metabolism, we carried out comparative genomic phylogenetic analysis CYP elephants. Our results suggest genes have undergone independent duplication, particularly CYP2A, CYP2C, CYP3A genes, unique cluster specific to species. However, while CYP2E CYP4A were conserved other Afrotheria taxa, their decay elephants resulted dysfunction (pseudogene). These findings outline several remarkable characteristics CYP1–4 provide new insights into xenobiotic metabolism. Further functional investigations are necessary characterize CYP, expression patterns interactions with sensitivities chemicals.

Language: Английский

Nontraditional biomanipulation: A powerful ecotechnology to combat cyanobacterial blooms in eutrophic freshwaters DOI Creative Commons

Jun Chen,

Jiarui Liu,

Shengpan Han

et al.

The Innovation Life, Journal Year: 2023, Volume and Issue: 1(3), P. 100038 - 100038

Published: Jan. 1, 2023

<p>Cyanobacterial blooms, occurring frequently in eutrophic freshwaters worldwide, are considered as potential hazards to ecosystems and human health, it is often difficult expensive control their outbreaks large lakes through reduction of nutrient loadings. Biomanipulation, launched an ecology-based solution the 1970s, was once believed be effective way counteract cyanobacterial blooms. It divided into traditional biomanipulation (TB) nontraditional (NTB) that use filter-feeding <i>Daphnia</i> fish, respectively. There have been numerous reviews on former, yet few latter. Here, we first revisit debate digestibility cyanobacteria silver bighead carp. Then, review 42 experiments clearly mention changes reveal substantial reductions abundance by carp 88% cases. In particular, a whole-lake experiment Lake Donghu, increased stock effectively decreased <i>Microcystis</i> blooms from coverage 87% 2021 0% 2022. Finally, discuss possible factors related NTB��s effectiveness depends not only standing stock, niche divergence shape preference fish but also trophic status waterbodies. Particularly, feed more colony-forming than filamentous cyanobacteria, capable increasing small-sized algae. NTB can used prevent or diminish poorly grazed <i>Daphnia</i>, providing sustainable in-lake ecotechnology combat heavy waterbodies.</p>

Language: Английский

Citations

45

Innovations in science, technology, engineering, and policy (iSTEP) for addressing environmental issues towards sustainable development DOI
Lei Luo, Junze Zhang, Haijun Wang

et al.

The Innovation Geoscience, Journal Year: 2024, Volume and Issue: 2(3), P. 100087 - 100087

Published: Jan. 1, 2024

<sec></sec><sec><p> Sustainable development depends on the integration of economy, society, and environment. Yet, escalating environmental challenges pose threats to both society economy. Despite progress in addressing issues promote sustainability, knowledge gaps scientific research, technological advancement, engineering practice, policy persist. In this review, we aim narrow these by proposing innovation-based solutions refining existing paradigms. Reviewing past research actions, first elucidate evolution sustainability science essence sustainable its assessment. Secondly, summarize current major issues, including global warming climate change, biodiversity loss, land degradation desertification, pollution, as well their relationships with achievement Development Goals (SDGs). Subsequently, review critically evaluates role innovations science, technology, engineering, (iSTEP) synergies advancing SDGs. While sequential may vary based specific contexts or scenarios within iSTEP framework, each component reinforces others, fostering continuous improvement. Finally, offers recommendations future perspectives for formulating roadmaps. Recommendations include a vision promoting interdisciplinary collaboration, encouraging transboundary cooperation among stakeholders endeavors.</p></sec>

Language: Английский

Citations

10

Will “Air Eutrophication” Increase the Risk of Ecological Threat to Public Health? DOI Creative Commons
Yan-Feng Sun, Yuming Guo, Chi Xu

et al.

Environmental Science & Technology, Journal Year: 2023, Volume and Issue: 57(29), P. 10512 - 10520

Published: July 10, 2023

Aquatic eutrophication, often with anthropogenic causes, facilitates blooms of cyanobacteria including cyanotoxin producing species, which profoundly impact aquatic ecosystems and human health. An emerging concern is that eutrophication may interact other environmental changes thereby lead to unexpected cascading effects on terrestrial systems. Here, we synthesize recent evidence showing the possibility accelerating will spill over from atmosphere via "air eutrophication", a novel concept refers process promoting growth airborne algae, some them capacity produce toxic compounds for humans organisms. Being catalyzed by various forcings─including climate warming, air contamination, artificial light at night─accelerated be expected in future, posing potentially increasing risk threat public health environment. So far knowledge this topic sparse, therefore consider important research field propose an agenda cross-discipline research. As contribution, have calculated tolerable daily intake 17 ng m–3 day–1 nasal microcystins humans.

Language: Английский

Citations

13

Nodding syndrome: A role for environmental biotoxins that dysregulate MECP2 expression? DOI Creative Commons
Peter S. Spencer, Raquel Valdes Angues,

Valerie S. Palmer

et al.

Journal of the Neurological Sciences, Journal Year: 2024, Volume and Issue: 462, P. 123077 - 123077

Published: June 2, 2024

Language: Английский

Citations

5

Probiotic Lactobacillus rhamnosus alleviates the neurotoxicity of microcystin-LR in zebrafish (Danio rerio) through the gut-brain axis DOI

Ning Luan,

Junli Zuo,

Qianping Niu

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 908, P. 168058 - 168058

Published: Oct. 31, 2023

Language: Английский

Citations

12

Detection of Aerosolized Anabaenopeptins from Cyanobacterial Harmful Algal Blooms in Atmospheric Particulate Matter DOI
Jia H. Shi,

Johnna A. Birbeck,

Nicole E. Olson

et al.

ACS Earth and Space Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 25, 2025

Language: Английский

Citations

0

Anaerobic Enrichment and Succession of Microcystin-Degrading Bacterial Communities from Shrimp Pond Sediment and Shrimp Intestine DOI Open Access
Wenjie Zhao, Xiangdong Bi, Xinyu Wang

et al.

Water, Journal Year: 2025, Volume and Issue: 17(6), P. 774 - 774

Published: March 7, 2025

Under anaerobic conditions, microcystins (MCs)-degrading bacteria from shrimp pond sediment and the intestine were repeatedly enriched using Widdel medium with MCs as sole source of carbon nitrogen. The succession two bacterial communities during enrichment was compared, MC-degrading strains isolated final communities. results showed that, increase in time, alpha diversity indices decreased significantly at first (p<0.05) then increased gradually, but difference not significant (p>0.05). composition dominant genera changed gradually stabilized. After six instances enrichment, had similar microbial essentially same genera. Principal coordinate analysis (PCoA) revealed differentiation original between intestine, no separation Compared communities, degradation rates by 1.01 times 1.42 times, respectively. Three identified Shewanella algae, Serratia marcescens, Bacillus flexu. They could all degrade MCs, there differences their rates, which differ more than 100 times. Our suggest that a common native community exists different sites pond, biodegradation plays an important role eliminating MC pollution ponds.

Language: Английский

Citations

0

Design of a Fractional-Order Environmental Toxin-Plankton System in Aquatic Ecosystems: A Novel Machine Predictive Expedition with Nonlinear Autoregressive Neuroarchitectures DOI

Muhammad Junaid Ali Asif Raja,

Amir Sultan, Chuan‐Yu Chang

et al.

Water Research, Journal Year: 2025, Volume and Issue: unknown, P. 123640 - 123640

Published: April 1, 2025

Language: Английский

Citations

0

The photoactivity of complexation of DOM and Fe(Ⅱ)/Mn(Ⅱ) in aquatic system: Implication on the photodegradation of MCLR DOI

Haishuo Wang,

Xiuchun Tian, Zhichun Li

et al.

Journal of environmental chemical engineering, Journal Year: 2025, Volume and Issue: unknown, P. 116703 - 116703

Published: April 1, 2025

Language: Английский

Citations

0

A proteomic study on gastric impairment in rats caused by microcystin-LR DOI
Shangchun Li, Lihong Gu, Yanfang Wang

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 917, P. 169306 - 169306

Published: Dec. 15, 2023

Language: Английский

Citations

9