Biomaterials Advances, Journal Year: 2024, Volume and Issue: 167, P. 214113 - 214113
Published: Nov. 8, 2024
Language: Английский
Biomaterials Advances, Journal Year: 2024, Volume and Issue: 167, P. 214113 - 214113
Published: Nov. 8, 2024
Language: Английский
ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: 17(2), P. 2791 - 2813
Published: Jan. 6, 2025
Transplantation of bone implants is currently recognized as one the most effective means treating defects. Biobased and biodegradable polyester composites combine good mechanical degradable properties polyester, thereby providing an alternative for implant materials. Bone tissue engineering (BTE) accelerates defect repair by simulating microenvironment. Composite scaffolds support formation further accelerate process repair. The introduction 3D printing technology enables preparation to be more precise, reproducible, flexible, which a very promising development. This review presents physical BTE summarizes strategies adopted domestic international scholars improve based on biobased polyester/ceramic in recent years. In addition, future development prospects field challenges expanding production clinical applications are presented.
Language: Английский
Citations
1Journal of Polymers and the Environment, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 18, 2025
Language: Английский
Citations
1Polymer Composites, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 8, 2025
Abstract Polylactic acid (PLA) has been widely utilized in the development of bone scaffolds. However, it is still constrained by issues, such as limited mechanical strength, slow degradation rate, low bioactivity, and suboptimal cell responses. In this study, a natural bioceramic fiber—wollastonite fiber (WF)—was incorporated into PLA matrix, PLA/WF composite scaffolds were fabricated via fused modeling deposition (FDM) 3D printing. The results indicated that properties initially enhanced with WF content, reaching optimal tensile compressive strength at 2.5 wt%, which 32.78% 25.80% higher, respectively, than those pure PLA. enhancement was ascribed to reinforcement effect WF, including breakage separation mechanisms. Furthermore, incorporation significantly accelerated scaffold degradation, attributed formation microvoids locally weak alkaline microenvironment due dissolvement WF. Additionally, release Si Ca ions from stimulated apatite development, enhancing biomineralization Moreover, improved cellular response osteogenic differentiation on These findings prove promising filler for simultaneously mechanical, biological performance biodegradable polymer tissue engineering (BTE) applications. Highlights FDM 3D‐printed showed orthogonal periodic ordered porous structure. through effect. released inorganic ion. promoted responses changing surface properties.
Language: Английский
Citations
0Applied Sciences, Journal Year: 2025, Volume and Issue: 15(5), P. 2578 - 2578
Published: Feb. 27, 2025
Prosthetics, a rapidly advancing field in dentistry, aims to improve patient comfort and aesthetics by addressing the challenge of replacing missing teeth. A critical obstacle dental implantation is condition jawbone, which often necessitates reconstruction prior implant placement. Guided bone regeneration (GBR) guided tissue (GTR) techniques utilize membranes that act as scaffolds for growth while serving barriers against proliferating cells pathogens. Commonly used membranes, such poly(tetrafluoroethylene) (PTFE) collagen, have significant limitations—PTFE non-bioresorbable requires secondary removal, collagen lacks adequate mechanical strength exhibits unpredictable degradation rates. To overcome these challenges, nanofiber produced via electrospinning using polylactic acid (PLA) were developed. The novel composites functionalized with bioactive additives, including periclase (MgO) nanoparticles polydopamine (PDA), enhance osteoblast adhesion, antibacterial properties, regeneration. This study comprehensively evaluated biological, mechanical, physicochemical properties prepared nanofibrous scaffolds. Experimental results revealed controlled rates improved hydrophilicity due surface modifications PDA MgO. Moreover, nanofibers exhibited enhanced swelling behavior, promoted nutrient exchange maintaining structural integrity over prolonged periods. incorporation additives contributed superior proliferation, activity, factor immobilization, supporting These findings suggest developed are promising candidate GBR GTR applications, offering balanced combination biological performance, behavior tailored clinical use.
Language: Английский
Citations
0Materials Today Chemistry, Journal Year: 2025, Volume and Issue: 45, P. 102635 - 102635
Published: March 13, 2025
Language: Английский
Citations
0International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141046 - 141046
Published: Feb. 1, 2025
Language: Английский
Citations
0ACS Applied Polymer Materials, Journal Year: 2025, Volume and Issue: unknown
Published: March 26, 2025
Language: Английский
Citations
0Journal of Materials Research and Technology, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Language: Английский
Citations
0International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 136751 - 136751
Published: Oct. 1, 2024
Language: Английский
Citations
2Applied Materials Today, Journal Year: 2024, Volume and Issue: 41, P. 102491 - 102491
Published: Nov. 7, 2024
Language: Английский
Citations
0