Exercise training upregulates CD55 to suppress complement-mediated synaptic phagocytosis in Parkinson’s disease DOI Creative Commons

Hongkai Yao,

Weifang Tong,

Yunping Song

et al.

Journal of Neuroinflammation, Journal Year: 2024, Volume and Issue: 21(1)

Published: Sept. 28, 2024

Language: Английский

Understanding the mechanisms of disease modifying effects of aerobic exercise in people with Alzheimer’s disease DOI
Auwal Abdullahi, Thomson W. L. Wong, Shamay S. M. Ng

et al.

Ageing Research Reviews, Journal Year: 2024, Volume and Issue: 94, P. 102202 - 102202

Published: Jan. 23, 2024

Language: Английский

Citations

8
Friend or foe: Lactate in neurodegenerative diseases DOI
Mingyu Wang, Yang Zhou,

Wenlian Li

et al.

Ageing Research Reviews, Journal Year: 2024, Volume and Issue: 101, P. 102452 - 102452

Published: Aug. 8, 2024

Language: Английский

Citations

8
Lactate Protects Microglia and Neurons from Oxygen–Glucose Deprivation/Reoxygenation DOI
Isadora D’Ávila Tassinari, Fernanda da Silva Rodrigues, Craig Bertram

et al.

Neurochemical Research, Journal Year: 2024, Volume and Issue: 49(7), P. 1762 - 1781

Published: March 29, 2024

Language: Английский

Citations

4
Physical exercise regulates microglia in health and disease DOI Creative Commons
Alexandra O. Strohm, Ania K. Majewska

Frontiers in Neuroscience, Journal Year: 2024, Volume and Issue: 18

Published: June 7, 2024

There is a well-established link between physical activity and brain health. As such, the effectiveness of exercise as therapeutic strategy has been explored in variety neurological contexts. To determine extent to which could be most beneficial under different circumstances, studies are needed uncover underlying mechanisms behind benefits activity. Interest grown understanding how can regulate microglia, resident immune cells central nervous system. Microglia key mediators neuroinflammatory processes play role maintaining homeostasis healthy pathological settings. Here, we explore evidence suggesting that potential microglia various animal models. We emphasize areas where future research contribute uncovering engaging exercise.

Language: Английский

Citations

4
High-intensity interval training and medium-intensity continuous training may affect cognitive function through regulation of intestinal microbial composition and its metabolite LPS by the gut-brain axis DOI

Mei Peng,

Ruihan Zou,

Sisi Yao

et al.

Life Sciences, Journal Year: 2024, Volume and Issue: 352, P. 122871 - 122871

Published: June 25, 2024

Language: Английский

Citations

4
Voluntary wheel exercise improves learning and memory impairment caused by hippocampal Hb-α deficiency by reducing microglial activation and reversing synaptic damage DOI
Yiying Wang,

Yuning Zhou,

Shun Wang

et al.

Brain Behavior and Immunity, Journal Year: 2025, Volume and Issue: 127, P. 81 - 95

Published: March 7, 2025

Language: Английский

Citations

0
Impact of Diet and Exercise on Mitochondrial Quality and Mitophagy in Alzheimer's disease DOI
Jangampalli Adi Pradeepkiran, Md. Ariful Islam,

Ujala Sehar

et al.

Ageing Research Reviews, Journal Year: 2025, Volume and Issue: unknown, P. 102734 - 102734

Published: March 1, 2025

Language: Английский

Citations

0
Treadmill Exercise Modulates the Leptin/LepR/GSK-3β Signalling Pathway to Improve Leptin Sensitivity and Alleviate Neuroinflammation in High-Fat Diet-Fed APP/PS1 Mice DOI

Juan Wang,

Meiqing Liao,

Zhen Tong

et al.

Molecular Neurobiology, Journal Year: 2025, Volume and Issue: unknown

Published: March 25, 2025

Language: Английский

Citations

0
Mapping the scientific research on exercise therapy for Alzheimer’s disease: a scientometric study of hotspots and emerging trends DOI Creative Commons
SuJin Song, Wendy Yu, Xin Cai

et al.

Frontiers in Aging Neuroscience, Journal Year: 2025, Volume and Issue: 17

Published: April 3, 2025

Background Alzheimer’s disease (AD) is the most common form of dementia globally, placing a substantial economic burden on patients and society. Exercise serves as an adjuvant therapy for AD with low incidence related adverse events. As non-pharmacological intervention, it has demonstrated significant potential in AD. Objective This study examines key hotspots emerging trends exercise AD, offering valuable insights researchers engaged future research this field. Methods The Web Science Core Collection database was utilized to search literature from January 1, 2000, November 2024, 1,372 relevant articles being identified. And CiteSpace 6.2.R4 VOSviewer were used evaluate bibliometric indicators. Results Since number publications field been increasing. In addition well-known areas research, such impact cognitive function, combination medication therapy, effects specific symptoms, music may also focus more novel topics. These include integration design implementation interventions, dendritic spines, neurophysiological mechanisms. Furthermore, analysis keywords reveals that current main direction exploring physiological mechanisms through which affects includes three trends: impairment patients, brain-derived neurotrophic factor (BDNF) Amyloid beta, influence Stress neuroinflammation. Conclusion results indicate interventions using alleviate negative symptoms well combining are gaining increasing attention researchers. Meanwhile, topics should attract scholarly interest. Additionally, behind could be research.

Language: Английский

Citations

0
Effects of home-based and telerehabilitation exercise on mental and physical health, and disease cost in people with Alzheimer’s disease: A meta-analysis DOI
Auwal Abdullahi, Thomson W. L. Wong, Shamay S. M. Ng

et al.

Ageing Research Reviews, Journal Year: 2024, Volume and Issue: 97, P. 102284 - 102284

Published: April 9, 2024

Language: Английский

Citations

2