Fabrication of 3D printed Si3N4 bioceramics with superior comprehensive performance through ZnO nanowires doping DOI Creative Commons
Xiaofeng Zeng, Coswald Stephen Sipaut, Noor Maizura Ismail

et al.

Ceramics International, Journal Year: 2024, Volume and Issue: 50(18), P. 34457 - 34466

Published: June 13, 2024

Silicon nitride (Si3N4) material holds significant potential as a widespread applied biomedical with high reliability in mechanical properties and biological activity. This study utilized 3D printing techniques to fabricate Si3N4 bioceramics reinforced zinc oxide (ZnO) nanowires, which overcomes the dilemma faced by traditional materials, possess excellent but lack sufficient antibacterial performance, or porous materials that exhibit good yet suffer from poor characteristics. Compared Ti-alloy, Al2O3, PEEK, conventional bioceramic an addition of 5 wt percent (wt%) ZnO nanowires retains superior properties: bending strength 735 MPa, fracture toughness 8.25 MPa m1/2, vickers hardness 14.8 GPa, compressive 2575 MPa. Furthermore, demonstrates commendable biocompatibility outstanding effects. Cellular activity on surface this is also noted be exceptionally vigorous. Research indicates synergistic effects characteristics appropriate inclusion positively interact β-Si3N4 crystals, are primarily responsible for exceptional comprehensive performance printed bioceramics.

Language: Английский

3D printing in upcycling plastic and biomass waste to sustainable polymer blends and composites: A review DOI Creative Commons
Malik Hassan, Amar K. Mohanty, Manjusri Misra

et al.

Materials & Design, Journal Year: 2023, Volume and Issue: 237, P. 112558 - 112558

Published: Dec. 13, 2023

Mishandling of waste plastics and biomasses is a major global concern. Every year, around 380 million tons plastic are produced, with only 9% being recycled, leading to widespread pollution. Similarly, biomass generation from agricultural forestry sectors accounts for 140 billion metric tons, in addition 2.01 municipal solid waste. This review paper addresses the gap regarding integration 3D printing, upcycling recycled plastics, utilization sustainable composites. printed parts have shown comparable mechanical properties compared virgin materials, which been further improved by biomass-derived fillers. The acknowledges that different printing parameters substantial influence on strength, ductility, crystallinity, dimensional accuracy parts. Therefore, optimizing these becomes crucial achieving performance. Moreover, incorporating reinforcing agents, stabilizers, chain extenders, compatibilizers, surface modifiers recycling presents an excellent opportunity enhance properties, thermal stability, adhesion, stability. Additionally, identifies research gaps proposes machine learning artificial intelligence enhanced process control material development, expanding possibilities this field.

Language: Английский

Citations

58
Design of bone scaffolds with calcium phosphate and its derivatives by 3D printing: A review DOI

Seyedeh Farnaz Darghiasi,

Ashkan Farazin,

Hanieh Sadat Ghazali

et al.

Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials, Journal Year: 2024, Volume and Issue: 151, P. 106391 - 106391

Published: Jan. 9, 2024

Language: Английский

Citations

20
Regenerative approaches in alveolar bone augmentation for dental implant placement: Techniques, biomaterials, and clinical decision-making: A comprehensive review DOI Creative Commons
Mohamed Elboraey, Ahmed Yaseen Alqutaibi, Afaf Noman Aboalrejal

et al.

Journal of Dentistry, Journal Year: 2025, Volume and Issue: unknown, P. 105612 - 105612

Published: Feb. 1, 2025

Language: Английский

Citations

3
Current status of nano-embedded growth factors and stem cells delivery to bone for targeted repair and regeneration DOI Creative Commons
Wenqing Liang, Chao Zhou, Xiankun Liu

et al.

Journal of Orthopaedic Translation, Journal Year: 2025, Volume and Issue: 50, P. 257 - 273

Published: Jan. 1, 2025

Language: Английский

Citations

2
Embedded 3D bioprinting – An emerging strategy to fabricate biomimetic & large vascularized tissue constructs DOI Creative Commons
Harshavardhan Budharaju, Dhakshinamoorthy Sundaramurthi, Swaminathan Sethuraman

et al.

Bioactive Materials, Journal Year: 2023, Volume and Issue: 32, P. 356 - 384

Published: Oct. 21, 2023

Three-dimensional bioprinting is an advanced tissue fabrication technique that allows printing complex structures with precise positioning of multiple cell types layer-by-layer. Compared to other methods, extrusion has several advantages print large-sized constructs and organ models due large build volume. Extrusion using sacrificial, support embedded strategies have been successfully employed facilitate hollow structures. Embedded a gel-in-gel approach developed overcome the gravitational overhanging limits micron-scale resolution. In bioprinting, deposition bioinks into microgel or granular bath will be facilitated by sol-gel transition through needle movement inside medium. This review outlines various polymers used in systems advantages, limitations, efficacy vascularized tissues Further, essential requirements like viscoelasticity, stability, transparency easy extraction human scale organs are discussed. Additionally, geometries vascular constructs, heart, bone, octopus jellyfish printed assisted methods their anatomical features elaborated. Finally, challenges clinical translation future scope these replace native envisaged.

Language: Английский

Citations

37
Emerging Biomedical and Clinical Applications of 3D-Printed Poly(Lactic Acid)-Based Devices and Delivery Systems DOI Creative Commons
Allan John R. Barcena, Prashanth Ravi, Suprateek Kundu

et al.

Bioengineering, Journal Year: 2024, Volume and Issue: 11(7), P. 705 - 705

Published: July 11, 2024

Poly(lactic acid) (PLA) is widely used in the field of medicine due to its biocompatibility, versatility, and cost-effectiveness. Three-dimensional (3D) printing or systematic deposition PLA layers has enabled fabrication customized scaffolds for various biomedical clinical applications. In tissue engineering regenerative medicine, 3D-printed been mostly generate bone scaffolds, typically combination with different polymers ceramics. PLA’s versatility also allowed development drug-eluting constructs controlled release agents, such as antibiotics, antivirals, anti-hypertensives, chemotherapeutics, hormones, vitamins. Additionally, recently develop diagnostic electrodes, prostheses, orthoses, surgical instruments, radiotherapy devices. provided a cost-effective, accessible, safer means improving patient care through dosimetry guides, well enhancing medical education training models simulators. Overall, widespread use settings expected persistently stimulate innovation revolutionize healthcare delivery.

Language: Английский

Citations

16
Calcium Phosphate Biomaterials for 3D Bioprinting in Bone Tissue Engineering DOI Creative Commons

Nelli Tolmacheva,

Amitava Bhattacharyya, Insup Noh

et al.

Biomimetics, Journal Year: 2024, Volume and Issue: 9(2), P. 95 - 95

Published: Feb. 6, 2024

Three-dimensional bioprinting is a promising technology for bone tissue engineering. However, most hydrogel bioinks lack the mechanical and post-printing fidelity properties suitable such hard regeneration. To overcome these weak properties, calcium phosphates can be employed in bioink to compensate of certain characteristics. Further, extracellular matrix natural contains this mineral, resulting its structural robustness. Thus, are necessary components This review paper examines different recently explored phosphates, as component potential bioinks, biological, required 3D bioprinted scaffolds, exploring their distinctive that render them favorable biomaterials The discussion encompasses recent applications adaptations 3D-printed scaffolds built with delving into scientific reasons behind prevalence types over others. Additionally, elucidates interactions polymer hydrogels applications. Overall, current status phosphate/hydrogel engineering has been investigated.

Language: Английский

Citations

14
Fused Deposition Modeling 3D-Printed Scaffolds for Bone Tissue Engineering Applications: A Review DOI
Pawan Kumar,

Shamim Shamim,

Mohammad Muztaba

et al.

Annals of Biomedical Engineering, Journal Year: 2024, Volume and Issue: 52(5), P. 1184 - 1194

Published: Feb. 28, 2024

Language: Английский

Citations

14
Advances in 3D printing of structural and functional ceramics: Technologies, properties, and applications DOI
Yixuan Wang, Yanyan Bu, Xiangfu Wang

et al.

Journal of the European Ceramic Society, Journal Year: 2024, Volume and Issue: 44(14), P. 116653 - 116653

Published: June 5, 2024

Language: Английский

Citations

14
Mechanical properties and biological activity of 3D printed silicon nitride materials DOI Creative Commons
Xiaofeng Zeng, Coswald Stephen Sipaut, Noor Maizura Ismail

et al.

Ceramics International, Journal Year: 2024, Volume and Issue: 50(9), P. 16704 - 16713

Published: Feb. 3, 2024

Silicon nitride (Si3N4) is a very promising biomedical material. Customization and reliability requirements are one of the prerequisites for achieving widespread application Si3N4 materials. This research used 3D printing method to achieve customized molding gas pressure sintering prepare dense ceramic material, investigated their mechanical properties biological activity. Compared with Ti-alloy, Al2O3, PEEK, printed materials have significant advantages in properties: bending strength 803 MPa, fracture toughness 8.86 MPa m1/2, vickers hardness 15.1 GPa, compressive 2725 MPa. Meanwhile, more stable excellent biocompatibility than other materials, obvious antibacterial performance, an rate 94.6 %. On surface cells good morphology, normal migration, conducive cell spreading, adhesion, cross-linking. Research has shown that melting deposition filling characteristics method, crystal-oriented growth microstructure beneficial effects Nitrogen elements main reasons these advantages.

Language: Английский

Citations

11