Preparation and Investigation of Cellulose Acetate/Gelatin Janus Nanofiber Wound Dressings Loaded with Zinc Oxide or Curcumin for Enhanced Antimicrobial Activity

Membranes, Journal Year: 2024, Volume and Issue: 14(5), P. 95 - 95

Published: April 23, 2024

The skin, as the largest organ, serves a protective barrier against external stimuli. However, when skin is injured, wound healing becomes complex process influenced by physiological conditions, bacterial infections, and inflammation. To improve of healing, variety dressings with antibacterial qualities have been created. Electrospun nanofibers gained significant attention in dressing research due to their large specific surface area unique structure. One interesting method for creating Janus-structured side-by-side electrospinning. This work used electrospinning make cellulose acetate/gelatin Janus nanofibers. Curcumin zinc oxide nanoparticles were added these We studied nanofibers' physicochemical characteristics abilities regulate small-molecule medication release. coated curcumin also tested activity. specified successfully fabricated. Nanofibers released medicines controlled manner. Additionally, loaded exhibited excellent capabilities. contributes development advanced promoting combating infections.

Language: Английский

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Versatility of electrospun Janus wound dressings

Nanomedicine, Journal Year: 2024, Volume and Issue: 20(3), P. 271 - 278

Published: Dec. 23, 2024

Electrospun nanofibers produced through single-fluid blending processes have successfully demonstrated their potential as highly effective wound dressings. However, electrospun Janus nanofibers, in which various chambers can be designed to load different active pharmaceutical ingredients into polymeric matrices, are further exhibiting versatility for promoting healing. This commentary declares that dressings always need multiple functional performances promote unique advantages, with parts interacting environments, thereby providing a versatile platform developing novel Two recent examples, each preparation strategy dressings, discussed, and the promising future of dressing applications is highlighted.

Language: Английский

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Electrospun photothermally active graphene-based nanofibers with a Retro-Diels-Alder reaction to initiate drug release

European Polymer Journal, Journal Year: 2024, Volume and Issue: 210, P. 112946 - 112946

Published: March 15, 2024

Language: Английский

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Electrospun lavender essential oil-loaded polylactic acid nanofibrous mats for antioxidant applications

Polymer Bulletin, Journal Year: 2024, Volume and Issue: 81(15), P. 13975 - 13992

Published: June 24, 2024

Abstract In this study, the lavender essential oil-incorporated polylactic acid (PLA) nanofibers were fabricated by electrospinning technique with presence of kolliphor as a nonionic surfactant. The FTIR spectra supported chemical composition fibers. demonstrated that there is no reaction present between PLA and oil. SEM images all showed bead-free morphology. ImageJ results average diameter oil-loaded fibers ranged 121.6 ± 32 228.2 53 nm. All hydrophobic satisfactory thermal properties. Furthermore, nanofibrous mats exhibited good antioxidant activity. concentration oil in resulting increased, activity also increased. According to can be considered for wide range potential applications such active packaging, food coating, facial masks, wound dressing.

Language: Английский

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Advances and applications of crosslinked electrospun biomacromolecular nanofibers

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 271, P. 132743 - 132743

Published: May 30, 2024

Language: Английский

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