Mechanically robust superhydrophobic and oleophobic nanofiber membranes with breathability, solvent-resistance, and high-temperature-resistance DOI Creative Commons
Xiang Liu, Jiqiang Cao, Junli Chen

et al.

Materials & Design, Journal Year: 2024, Volume and Issue: 244, P. 113153 - 113153

Published: July 9, 2024

Protective materials that can ensure the safety of personnel and equipment in extreme environments have a wide range application prospects, such as outdoor protective clothing, fire-fighting etc. However, designing highly functional is still considered long-standing challenge. Herein, superhydrophobic oleophobic fibrous membranes (SOFM) prepared by electrospinning, heat treatment spraying techniques, endowing with good thermal stability, air permeability outstanding repellence to liquids water, oil low surface energy solvents. The developed SOFM exhibits integrated properties ethanol intrusion pressure 0.75 KPa, excellent 1.54 mm/s, water vapor transmission rate 7.99 kg·m−2·d-1, high decomposition temperature 330 ℃, tensile strength 9.2 MPa. Therefore, effectively protect people environments. This work may contribute design fiber higher protection levels field clothing.

Language: Английский

Electrospun radially oriented berberine-PHBV nanofiber dressing patches for accelerating diabetic wound healing DOI Creative Commons
Qiuyu Wang, Sai Zhang, Jiayi Jiang

et al.

Regenerative Biomaterials, Journal Year: 2024, Volume and Issue: 11

Published: Jan. 1, 2024

Abstract A dressing patch made of radially oriented poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) nanofibers was successfully manufactured with a modified electrospinning strategy. The as-electrospun PHBV nanofiber exhibited uniform and bead-free nanofibrous morphology innovative arrangement, which demonstrated to possess obviously improved mechanical property, increased surface hydrophilicity enhanced biological properties compared the control traditionally randomly pattern. Interestingly, it found that pattern could induce cell migration from periphery center along in rapid manner. To further improve biofunction patch, berberine (Beri, an isoquinoline alkaloid) two different concentrations were encapsulated into during electrospinning, present sustained drug release behavior for nearly one month. Importantly, addition Beri impart excellent anti-inflammatory property by significantly inhibiting secretion pro-inflammatory factors M1 macrophages, also showed additive influence on promoting proliferation human dermal fibroblasts (HDFs), as well growth E. coli, S. aureus C. albicans, Beri-free patch. In animal studies, electrospun loading high content accelerate healing process diabetic mouse full-thickness skin wound shortened time (100% closure rate after 18 days’ treatment) quality (improved collagen deposition, re-epithelialization neovascularization hair follicles). all, this study reported therapeutic strategy integrating physical cues multiple effective treatment hard-to-heal wounds.

Language: Английский

Citations

33
Synergistic effect of Cydonia oblonga and its extracted silver nanoparticles for improving antioxidant and antibacterial activity of 3D printed alginate-based hydrogel as wound dressing DOI
Ali Ashtariyan, Hamid Mollania,

Nafiseh Annabestani

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 276, P. 133989 - 133989

Published: July 31, 2024

Language: Английский

Citations

8
Cyclodextrin nanocarriers in Coordination Chemistry: Enhancing encapsulation and targeted delivery of 5-Fluorouracil for cancer treatment DOI Creative Commons
Sara Payamifar, Amin Foroozandeh, Mehrab Pourmadadi

et al.

Results in Chemistry, Journal Year: 2024, Volume and Issue: 12, P. 101878 - 101878

Published: Oct. 30, 2024

Language: Английский

Citations

8
Metal-organic framework-hydrogel composites as emerging platforms for enhanced wound healing applications: Material design, therapeutic strategies, and future prospects DOI
Fereshte Hassanzadeh‐Afruzi, Majid Abdouss, Ehsan Nazarzadeh Zare‬

et al.

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 524, P. 216330 - 216330

Published: Nov. 14, 2024

Language: Английский

Citations

4
Autonomous living materials and bone-inspired scaffolds motivated by human osteogenic microenvironment mechanisms DOI Creative Commons
Yutong Chen, Seeram Ramakrishna,

Zhengyang Jin

et al.

Materials & Design, Journal Year: 2024, Volume and Issue: 244, P. 113145 - 113145

Published: July 8, 2024

The repair of secondary critical bone defects is an international medical challenge. Bone tissue engineering provides methods and technology for repair. regeneration mechanism serves as inspiration the material structural design scaffolds. In terms materials, this review draws from biological characteristics host cells in osteogenic microenvironment (including osteoblast lineage, vascular cell inflammatory cells, etc.), reviewing regulatory mechanisms self-healing proposing autonomous living materials scaffolds which prepared by in-situ manufacturing. Autonomous regulate migration, proliferation differentiation real time releasing steadily long-term. Regarding structure, we functional role natural structures homeostasis, providing insights into bone-inspired Due to conflict between mechanical properties ability, proposes assembled They can prolong half-life provide support attachment points new growth, autonomously microenvironment. have potential advance research progress field pave way novel clinical treatments.

Language: Английский

Citations

4
Multifunctional coaxial gelatin/polylactic acid three-dimensional nanofibrous scaffolds for diabetic wounds DOI
Xin Chen, Jingwen Wu, Tong Zhang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141525 - 141525

Published: Feb. 1, 2025

Language: Английский

Citations

0
Progress in Advanced Composite Hydrogel Dressings: Innovative Materials and Designs for the Treatment of Chronic Wounds DOI
Z T Sun, Li Zhao, Fenglong Wang

et al.

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(8)

Published: Feb. 1, 2025

Abstract Chronic wounds, as a kind of long‐term disease that is difficult to cure, are challenged in healthcare, placing substantial physical, emotional, and economic burdens on patients society. Effective treatment chronic wounds essential for improving patient quality life, reducing healthcare costs, alleviating the strain medical resources. Hydrogel materials have emerged promising candidates wound due their exceptional adaptability environments ability deliver various therapeutic agents, effectively promoting healing wounds. However, wide array available with diverse functionalities presents challenge selecting most appropriate components synthesizing hydrogel dressings. This review summarizes common materials, including properties, cross‐linking methods, applications. Additionally, it systematically categorizes different elucidating action mechanisms effects. Furthermore, this work offers guidance material selection dressing design based characteristics Finally, challenges future perspectives composite hydrogels field dressings discussed. provides readers comprehensive understanding reliable basis synthesize ideal

Language: Английский

Citations

0
Nature-Inspired Healing: Biomimetic Nanomaterials for Advanced Wound Management DOI

Elnaz Sarrami-Foroushani,

Maryam Yavari, Atefeh Zarepour

et al.

Materials Today Sustainability, Journal Year: 2024, Volume and Issue: 28, P. 100975 - 100975

Published: Sept. 6, 2024

Language: Английский

Citations

3
Development of 5-fluorouracil/etoposide co-loaded electrospun nanofibrous scaffold for localized anti-melanoma therapy DOI Creative Commons
Shirin Shojaei, Mahtab Doostan,

Hamid-Reza Mohammadi Motlagh

et al.

Journal of Applied Biomaterials & Functional Materials, Journal Year: 2024, Volume and Issue: 22

Published: Jan. 1, 2024

Nanofibrous scaffolds have emerged as promising candidates for localized drug delivery systems in the treatment of cutaneous cancers. In this study, we prepared an electrospun nanofibrous scaffold incorporating 5-fluorouracil (5-FU) and etoposide (ETP) chemotherapy targeting melanoma cancer. The was composed polyvinyl alcohol (PVA) chitosan (CS), via electrospinning process loaded with chemotherapeutic agents. We conducted relevant physicochemical characterizations, assessed cytotoxicity, evaluated apoptosis against A375 cells. 5-FU/ETP co-loaded PVA/CS exhibited nanofibers (NFs) average diameter 321 ± 61 nm, defect-free homogenous morphology. FTIR spectroscopy confirmed successful incorporation chemotherapeutics into scaffold. Additionally, demonstrated a hydrophilic surface, proper mechanical strength, high porosity, efficient liquid absorption capacity. Notably, sustained controlled release observed from Furthermore, significantly increased cytotoxicity (95%) (74%) Consequently, holds promise valuable system eradication tumors mitigation adverse reactions associated chemotherapy.

Language: Английский

Citations

3
Mechanically robust superhydrophobic and oleophobic nanofiber membranes with breathability, solvent-resistance, and high-temperature-resistance DOI Creative Commons
Xiang Liu, Jiqiang Cao, Junli Chen

et al.

Materials & Design, Journal Year: 2024, Volume and Issue: 244, P. 113153 - 113153

Published: July 9, 2024

Protective materials that can ensure the safety of personnel and equipment in extreme environments have a wide range application prospects, such as outdoor protective clothing, fire-fighting etc. However, designing highly functional is still considered long-standing challenge. Herein, superhydrophobic oleophobic fibrous membranes (SOFM) prepared by electrospinning, heat treatment spraying techniques, endowing with good thermal stability, air permeability outstanding repellence to liquids water, oil low surface energy solvents. The developed SOFM exhibits integrated properties ethanol intrusion pressure 0.75 KPa, excellent 1.54 mm/s, water vapor transmission rate 7.99 kg·m−2·d-1, high decomposition temperature 330 ℃, tensile strength 9.2 MPa. Therefore, effectively protect people environments. This work may contribute design fiber higher protection levels field clothing.

Language: Английский

Citations

2