Green Synthesis of Zinc Oxide (ZnO) Nanoparticles Using Aqueous Fruit Extracts of Myristica fragrans: Their Characterizations and Biological and Environmental Applications

ACS Omega, Journal Year: 2021, Volume and Issue: 6(14), P. 9709 - 9722

Published: March 30, 2021

In the present work, bioaugmented zinc oxide nanoparticles (ZnO-NPs) were prepared from aqueous fruit extracts of Myristica fragrans. The ZnO-NPs characterized by different techniques such as X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, ultraviolet (UV) scanning electron microscopy (SEM), transmission (TEM), dynamic light scattering (DLS), and thermogravimetric analysis (TGA). crystallites exhibited a mean size 41.23 nm measured via XRD highly pure, while SEM TEM analyses synthesized NPs confirmed their spherical or elliptical shape. functional groups responsible for stabilizing capping using FTIR analysis. ζ-size ζ-potential reported 66 −22.1 mV, respectively, DLS technique can be considered moderate stable colloidal solution. Synthesized used to evaluate possible antibacterial, antidiabetic, antioxidant, antiparasitic, larvicidal properties. found active against bacterial strains both coated with antibiotics alone. Klebsiella pneumoniae was most sensitive strain (27 ± 1.73) imipinem (26 1.5). displayed outstanding inhibitory potential enzymes protein kinase (12.23 0.42), α-amylase (73.23 α-glucosidase (65.21 0.49). Overall, have shown significant activity (77.3 1.8) Aedes aegypti, mosquitoes involved in dengue fever. Similarly, tremendous leishmanicidal also observed promastigote (71.50 0.70) amastigote (61.41 0.71) forms parasite. biosynthesized excellent antioxidant biocompatible nanomaterials. Biosynthesized photocatalytic agents, resulting 88% degradation methylene blue dye 140 min. Owing eco-friendly synthesis, nontoxicity, nature, M. fragrans exploited candidates biomedical environmental applications.

Language: Английский

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Chitosan nanofiber biocomposites for potential wound healing applications: Antioxidant activity with synergic antibacterial effect

Bioengineering & Translational Medicine, Journal Year: 2021, Volume and Issue: 7(1)

Published: Sept. 9, 2021

Abstract Bacterial wound infection is one of the most common nosocomial infections. The unnecessary employment antibiotics led to raising growth antibiotic‐resistant bacteria. Accordingly, alternative armaments capable accelerating healing along with bactericidal effects are urgently needed. Considering this, we fabricated chitosan (CS)/polyethylene oxide (PEO) nanofibers armed antibacterial silver and zinc nanoparticles. nanocomposites exhibited a high antioxidant effect activity against Staphylococcus aureus , Escherichia coli Pseudomonas aeruginosa . Besides, based on results cell viability assays, optimum concentration ZnONPs AgNPs in nanofibrous mats 0.2% w/v 0.08% respectively had no cytotoxicity fibroblast cells. scaffold also showed good blood compatibility according coagulation time. As well as significant migration proliferation margin, wound‐healing assay. All all, developed biocompatible, antioxidant, Ag‐ZnO NPs incorporated CS/PEO their potential an effective dressing.

Language: Английский

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A Review on Green Synthesis of Zinc Oxide Nanoparticles Using Plant Extracts and Its Biomedical Applications

BioNanoScience, Journal Year: 2020, Volume and Issue: 10(4), P. 848 - 863

Published: July 22, 2020

Language: Английский

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Nanotechnology in ovarian cancer: Diagnosis and treatment

Life Sciences, Journal Year: 2020, Volume and Issue: 266, P. 118914 - 118914

Published: Dec. 16, 2020

Language: Английский

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Green Synthesis of Metal and Metal Oxide Nanoparticles: Principles of Green Chemistry and Raw Materials

Magnetochemistry, Journal Year: 2021, Volume and Issue: 7(11), P. 145 - 145

Published: Oct. 31, 2021

Increased request for metal and oxide nanoparticles has led to their large-scale production using high-energy methods with various toxic solvents. This cause environmental contamination, thus eco-friendly "green" synthesis become necessary. An alternative way synthesize includes bioresources, such as plants plant products, bacteria, fungi, yeast, algae, etc. "Green" low toxicity, is safe human health environment compared other methods, meaning it the best approach obtaining nanoparticles. review reveals 12 principles of chemistry examples biological components suitable synthesis, well modern scientific research magnetic Particularly, extracts green tea, fruits, roots, leaves, etc., obtain Fe3O4 NPs. The precursors egg white (albumen), leaf fruit extracts, can be used spinel are being widely antimicrobials, photocatalysts adsorbents. demonstrate toxicity high biocompatibility, which allows biomedical application, especially targeted drug delivery, contrast imaging hyperthermia applications. silver, gold, platinum palladium from red been described.

Language: Английский

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Nanomaterials for Diagnosis and Treatment of Brain Cancer: Recent Updates

Chemosensors, Journal Year: 2020, Volume and Issue: 8(4), P. 117 - 117

Published: Nov. 20, 2020

Brain tumors, especially glioblastoma, remain the most aggressive form of all cancers because inefficient diagnosis and profiling. Nanostructures, such as metallic nanostructures, silica nano-vehicles, quantum dots, lipid nanoparticles (NPs) polymeric NPs, with high specificity have made it possible to permeate blood–brain barrier (BBB). NPs possess optical, magnetic photodynamic properties that can be exploited by surface modification, bio composition, contrast agents’ encapsulation coating tumor-derived cells. Hence, nanotechnology has brought on a revolution in field imaging brain tumors cancers. Recently, nanomaterials biomimetic functions been introduced efficiently cross BBB engulfed deep skin cancer malignancies for imaging. The review focuses nanotechnology-based diagnostic approaches exploration Moreover, also summarizes few strategies image glioblastoma multimodal functional nanocomposites more precise accurate clinical diagnosis. Their unique physicochemical attributes, including nanoscale sizes, larger area, explicit structural features ability encapsulate diverse molecules their surface, render nanostructured materials excellent nano-vehicles convey drug target region. This sheds light current progress various kinds nanomaterials, liposomes, nano-micelles, dendrimers, carbon nanotubes, dots (gold, silver zinc oxide NPs), efficient delivery treatment cancer.

Language: Английский

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Antibacterial and cytotoxic potency of the plant-mediated synthesis of metallic nanoparticles Ag NPs and ZnO NPs: A review

OpenNano, Journal Year: 2022, Volume and Issue: 8, P. 100077 - 100077

Published: Aug. 28, 2022

Green synthesis approaches of metal nanoparticles and oxide from plant extracts have become a focus research attention in an era environmentally friendly development due to the simplicity, low cost, benefits environmental sustainability compared chemical physical routes. This current review article introduces data 85 selected articles that were synthesized ZnO NPs Ag using different parts (such as leaves, fruits, flowers, stems, bark, rhizomes, roots, seeds), with specific on their biomedical applications are 40 antibacterial properties mechanism action .in addition anticancer potential (in vitro) at time or dose-independent MTT assay 5 studies vivo). Several used model cell lines exhibit cytotoxicity ZnONPs AgNPs. Different proved particle size shape is significant factor indicates antimicrobial effectiveness NPs. Our results showed Ag-NPs display excellent for both metal/metal biocompatibility.

Language: Английский

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Recent advances in green synthesized nanoparticles: from production to application

Materials Today Sustainability, Journal Year: 2023, Volume and Issue: 24, P. 100500 - 100500

Published: Aug. 19, 2023

With the increasing concern over environmental impact of conventional chemical methods, environmentally friendly processes, commonly known as green chemistry, for synthesis nanoparticles have gained growing interest in field nanobiotechnology. This review focuses on metallic (NPs) based chemistry and their applications new drug delivery system anticancer antimicrobial treatment. The encompasses a survey production characterization synthetic NPs, along with an examination physico-chemical properties biological activities. Notably, this goes beyond previous reports by providing extensive analysis recent studies that utilize silico design computational modeling to gain deeper insights into interactions between these NPs targets. simulation helps not only comprehending mechanism but also predicting any potential bioactivities. By offering broad perspective novel ideas, attempts shed light future development smart medicine modern generation cancer therapy other disease treatments.

Language: Английский

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Environmentally Safe Biosynthesis of Gold Nanoparticles Using Plant Water Extracts

Nanomaterials, Journal Year: 2021, Volume and Issue: 11(8), P. 2033 - 2033

Published: Aug. 10, 2021

Due to their simplicity of synthesis, stability, and functionalization, low toxicity, ease detection, gold nanoparticles (AuNPs) are a natural choice for biomedical applications. AuNPs’ unique optoelectronic features have subsequently been investigated used in high-tech applications such as organic photovoltaics, sensory probes, therapeutic agents, the administration drugs biological medical applications, electronic devices, catalysis, etc. Researchers demonstrated biosynthesis AuNPs using plants. The present study evaluates 109 plant species traditional medicine Middle East countries new sources wide variety laboratory environments. In this study, dried samples bark, bulb, flower, fruit, gum, leaf, petiole, rhizome, root, seed, stamen, above-ground parts were evaluated water extracts. About 117 screened from 54 families, with 102 extracts demonstrating bioreduction Au3+ Au0, revealing 37 regard. color change biosynthesized gray, violet, or red was confirmed by UV-Visible spectroscopy, TEM, FSEM, DLS, EDAX six various sizes measured 27 107 nm. This also includes an evaluation potency Asian medicinal plants AuNPs. An environmentally safe procedure could act foundation cosmetic industries whose quality assessment systems give high priority non-chemically synthesized products. It is crucial that future optimizations adequately documented scale up described process.

Language: Английский

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Role of agrochemical-based nanomaterials in plants: biotic and abiotic stress with germination improvement of seeds

Plant Growth Regulation, Journal Year: 2022, Volume and Issue: 97(2), P. 375 - 418

Published: Jan. 4, 2022

Language: Английский

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