Materials Advances, Journal Year: 2022, Volume and Issue: 3(21), P. 7687 - 7708
Published: Jan. 1, 2022
As one of the current research hotspots, drug release nanoplatforms have great potential in treatment autoimmune inflammatory diseases.
Language: Английский
International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(8), P. 4339 - 4339
Published: April 14, 2022
The use of nanoparticles (NPs) has surely grown in recent years due to their versatility, with a spectrum applications that range from nanomedicine the food industry. Recent research focuses on development NPs for oral administration route rather than intravenous one, placing interactions between and intestine at centre attention. This allows functionalization exploit different characteristics digestive tract, such as pH, intestinal mucus layer, or absorption capacity. On other hand, these same can represent problem complexity, also considering potential matrix microbiota. review intends give comprehensive look into three main branches delivery through route: drug carriers systemic targets, case insulin an example; drugs locally active intestine, treatment inflammatory bowel diseases colon cancer; finally, concerns side effects accidental uncontrolled exposure employed additives, focus E171 (titanium dioxide) E174 (silver NPs).
Language: Английский
Citations
62
Journal of Materials Chemistry B, Journal Year: 2022, Volume and Issue: 10(31), P. 5853 - 5872
Published: Jan. 1, 2022
As a group of chronic and idiopathic gastrointestinal (GI) disorders, inflammatory bowel disease (IBD) is characterized by recurrent intestinal mucosal inflammation.
Language: Английский
Citations
59
International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 232, P. 123229 - 123229
Published: Jan. 13, 2023
Language: Английский
Citations
33
Materials, Journal Year: 2023, Volume and Issue: 16(6), P. 2364 - 2364
Published: March 15, 2023
Biopolymers are polymers obtained from either renewable or non-renewable sources and the most suitable candidate for tailor-made nanoparticles owing to their biocompatibility, biodegradability, low toxicity immunogenicity. Biopolymeric (BPn) can be classified as natural (polysaccharide protein based) synthetic on basis of origin. They have been gaining wide interest in biomedical applications such tissue engineering, drug delivery, imaging cancer therapy. BPn synthesized by various fabrication strategies emulsification, ionic gelation, nanoprecipitation, electrospray drying so on. The main aim review is understand use biodegradable biopolymers applications. There very few reviews highlighting biopolymeric employed medical applications; this an attempt explore possibilities using these materials This highlights based (albumin, gelatin, collagen, silk fibroin); polysaccharide (chitosan, starch, alginate, dextran) (Poly lactic acid, Poly vinyl alcohol, caprolactone) that has recently used many different also being highlighted. future perspective challenges faced employing reviewed.
Language: Английский
Citations
30
Polymers, Journal Year: 2023, Volume and Issue: 15(21), P. 4327 - 4327
Published: Nov. 5, 2023
In recent years, there has been a growing interest in the use of gelatin nanoparticles (GNPs) for treatment infectious diseases. The inherent properties these make them attractive options drug delivery. Their biocompatibility ensures that they can interact with biological systems without causing adverse reactions, while their biodegradability break down harmlessly body once function is performed. Furthermore, capacity controlled release therapeutic agents be delivered over sustained period, thereby enhancing efficacy. This review examines current landscape GNP-based delivery, specific focus on its potential applications and challenges context Key include controlling rates, ensuring nanoparticle stability under physiological conditions, scaling up production maintaining quality, mitigating immunogenic optimizing loading efficiency, tracking biodistribution clearance GNPs body. Despite hurdles, hold promising realm disease treatment. Ongoing research innovation are essential to overcome obstacles completely harness clinical applications.
Language: Английский
Citations
27
Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 93, P. 105436 - 105436
Published: Feb. 1, 2024
Nanotechnology in the field of pediatric dentistry offers innovative solutions to challenges. In this literature review, nanomaterials application dentistry, addressing critical concerns, such as toxicity and regulatory hurdles, is discussed. Also, unique physicochemical properties nanomaterials, including size, biocompatibility, drug delivery capabilities are explored. The safety efficacy nanoscale therapeutics were found be before their use dentistry. Polymer-based systems, especially those using natural polysaccharides, demonstrate great potential prevalent dental issues children. These systems can perform targeted therapy, reduce dosages, minimize side effects, making them beneficial for addition, future personalized treatments While advantages applying nanotechnology readily apparent, ongoing research should performed maximize its address
Language: Английский
Citations
13
Biomaterials, Journal Year: 2024, Volume and Issue: 314, P. 122822 - 122822
Published: Sept. 12, 2024
Language: Английский
Citations
9
Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: 250, P. 114545 - 114545
Published: Feb. 1, 2025
Language: Английский
Citations
1
Biomaterials Science, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Ulcerative colitis (UC) is a chronic inflammatory condition affecting the colon part of large intestine.
Language: Английский
Citations
1
Carbohydrate Polymers, Journal Year: 2021, Volume and Issue: 258, P. 117600 - 117600
Published: Jan. 13, 2021
Language: Английский
Citations
56