Neuropsychologia,
Journal Year:
2021,
Volume and Issue:
160, P. 107976 - 107976
Published: July 24, 2021
Endel
Tulving's
episodic
memory
framework
emphasizes
the
multifaceted
re-experiencing
of
personal
events.
Indeed,
decades
research
focused
on
experiential
nature
memories,
usually
treating
recent
as
a
coherent
quality.
However,
insights
into
functional
architecture
medial
temporal
lobe
show
that
different
types
mnemonic
information
are
segregated
distinct
neural
pathways
in
brain
circuits
empirically
associated
with
memory.
Moreover,
memories
do
not
fade
whole
under
conditions
progressive
neurodegeneration
these
circuits,
notably
Alzheimer's
disease.
Instead,
certain
content
seem
particularly
vulnerable
from
moment
their
encoding
while
other
can
remain
memorable
consistently
across
individuals
and
contexts.
We
propose
observations
related
to
content-specific
consequently
impairment
at
stages
neurodegeneration.
To
develop
inspirational
legacy
further
advance
our
understanding
how
function
is
affected
by
neurodegenerative
such
disease,
we
postulate
it
compelling
focus
representational
memories.
Journal of Experimental Psychology General,
Journal Year:
2024,
Volume and Issue:
153(1), P. 200 - 223
Published: Jan. 1, 2024
Aging
results
in
less
detailed
memories,
reflecting
reduced
fidelity
of
remembered
compared
to
real-world
representations.
We
tested
whether
poorer
representational
across
perception,
short-term
memory
(STM),
and
long-term
(LTM)
are
among
the
earliest
signs
cognitive
aging.
Our
paradigm
probed
target-lure
object
mnemonic
discrimination
precision
object-location
binding.
Across
lifespan,
deficits
were
observed
midlife
when
stimulus
representations
required
for
perceptual
short/long-term
forced
choice
discrimination.
A
continuous
metric
source
combined
with
computational
modeling
demonstrated
that
errors
STM
LTM
middle-aged
adults
largely
driven
by
a
loss
retrieved
not
necessarily
forgetting.
On
trial-by-trial
basis,
item
spatial
information
was
more
tightly
bound
this
association
being
unaffected
age.
Standard
neuropsychological
tests
without
demands
on
quality
(digit
span,
verbal
learning)
sensitive
age
effects
than
precision.
Perceptual
predicted
Neuropsychological
proxies
prefrontal
executive
functions
correlated
STM,
but
fidelity.
Conversely,
indicators
hippocampal
integrity
both
LTM,
suggesting
partially
dissociable
mechanisms
interindividual
variability
These
findings
suggest
is
hallmark
aging
can
be
from
onward.
Continuous
tasks
may
promising
early
detection
subtle
age-related
decline.
(PsycInfo
Database
Record
(c)
2024
APA,
all
rights
reserved).
Annual Review of Psychology,
Journal Year:
2021,
Volume and Issue:
73(1), P. 159 - 186
Published: Sept. 30, 2021
The
ability
to
remember
events
in
vivid,
multisensory
detail
is
a
significant
part
of
human
experience,
allowing
us
relive
previous
encounters
and
providing
with
the
store
memories
that
shape
our
identity.
Recent
research
has
sought
understand
subjective
experience
remembering,
is,
what
it
feels
like
have
memory.
Such
remembering
involves
reactivating
sensory-perceptual
features
an
event
thoughts
feelings
we
had
when
occurred,
integrating
them
into
conscious
first-person
experience.
It
allows
reflect
on
content
make
judgments
about
them,
such
as
distinguishing
actually
occurred
from
those
might
imagined
or
been
told
about.
In
this
review,
consider
recent
evidence
functional
neuroimaging
healthy
participants
studies
neurological
psychiatric
conditions,
which
shedding
new
light
how
subjectively
remembering.
Neuroscience & Biobehavioral Reviews,
Journal Year:
2021,
Volume and Issue:
133, P. 104489 - 104489
Published: Dec. 17, 2021
The
field
of
neurocognition
is
currently
undergoing
a
significant
change
perspective.
Traditional
neurocognitive
models
evolved
into
an
integrative
and
dynamic
vision
cognitive
functioning.
Dynamic
integration
assumes
interaction
between
domains
traditionally
considered
to
be
distinct.
Language
declarative
memory
are
regarded
as
separate
functions
supported
by
different
neural
systems.
However,
they
also
share
anatomical
structures
(notably,
the
inferior
frontal
gyrus,
supplementary
motor
area,
superior
middle
temporal
hippocampal
complex)
processes
(such
semantic
working
memory)
that
merge
endorse
our
quintessential
daily
lives.
We
propose
new
model,
"L∪M"
(i.e.,
Language/union/Memory),
considers
these
two
interactively.
fractionated
language
three
fundamental
dimensions
or
systems
("Receiver-Transmitter",
"Controller-Manager"
"Transformer-Associative"
Systems),
communicate
reciprocally.
formalized
their
interactions
at
brain
level
with
connectivity-based
approach.
This
taxonomy
overcomes
modular
view
functioning
reconciles
functional
specialization
plasticity
in
neurological
disorders.
NeuroImage,
Journal Year:
2022,
Volume and Issue:
254, P. 119123 - 119123
Published: March 20, 2022
The
involvement
of
the
medial
temporal
lobe
(MTL)
in
working
memory
is
controversially
discussed.
Recent
findings
suggest
that
persistent
neural
firing
hippocampus
during
maintenance
verbal
associated
with
workload.
Here,
we
recorded
single
neuron
13
epilepsy
patients
(7
male)
while
they
performed
a
visual
task.
number
colored
squares
stimulus
set
determined
workload
trial.
Performance
was
almost
perfect
for
low
(1
and
2
squares)
dropped
at
high
(4
6
squares),
suggesting
exceeded
capacity.
We
identified
neurons
MTL
showed
period.
More
were
found
trials
correct
compared
to
incorrect
performance.
Maintenance
increased
decreased
entorhinal
cortex
Population
predicted
particularly
Prediction
accuracy
based
on
single-trial
activity
strongest
hippocampus.
data
reflects
domain-general
process
supporting
performance
multiple
items
below
beyond
Persistent
may
be
its
preference
visual-spatial
arrays.
