Gels, Journal Year: 2025, Volume and Issue: 11(2), P. 123 - 123
Published: Feb. 7, 2025
Recent advancements in wound dressing materials have significantly improved acute and chronic management by addressing challenges such as infection control, moisture balance, enhanced healing. Important progress has been made, especially with hydrogels, foams, antimicrobial for creating optimized dressings. Hydrogels are known maintaining optimal levels, while foam dressings excellent exudate absorbents. Meanwhile, incorporates various agents to reduce risks. These options healing time focusing on customized patient needs. Therefore, this review highlights the newest research prototypes applications, emphasizing their particular benefits clinical importance. Innovations stimuli-responsive hydrogels hybrid bioengineered composites discussed relation properties, including responsiveness pH, temperature, glucose, or enzymes drug delivery precision. Moreover, ongoing trials included, demonstrating potential of emerging solutions be soon translated from laboratory settings. By discussing interdisciplinary approaches that integrate advanced materials, nanotechnology, biological insights, work provides a contemporary framework patient-centric, efficient care strategies.
Language: Английский
Citations
5Extraction and characterization of Bougainvillea glabra fibers: A study on chemical, physical, mechanical and morphological properties
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 275, P. 133787 - 133787
Published: July 9, 2024
Language: Английский
Citations
13Therapeutic Potential of Nanocarrier Mediated Delivery of Peptides for Wound Healing: Current Status, Challenges and Future Prospective
AAPS PharmSciTech, Journal Year: 2024, Volume and Issue: 25(5)
Published: May 10, 2024
Language: Английский
Citations
10A novel pH/ROS dual responsive engineering hydrogels based on poly(tannic acid)-assisted surface deposition of nano-enzymes with efficient antibacterial and antioxidant activity for diabetic wound healing
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 496, P. 153370 - 153370
Published: June 20, 2024
Language: Английский
Citations
10Application of polysaccharide-based crosslinking agents based on schiff base linkages for biomedical scaffolds
Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 345, P. 122585 - 122585
Published: Aug. 8, 2024
Language: Английский
Citations
8Multi-functional Dressings for Recovery and Screenable Treatment of Wounds: A review
Heliyon, Journal Year: 2024, Volume and Issue: 11(1), P. e41465 - e41465
Published: Dec. 24, 2024
Language: Английский
Citations
6Avanços, Desafios E Estratégias Em Terapias De Feridas: Abordagens Conservadoras, Tecnológicas E Biopoliméricas
Published: Jan. 14, 2025
Wound treatment represents a significant clinical challenge, requiring strategies that combine traditional approaches and technological innovations. The article analyzes advances in vacuum dressings, biopolymers nanotechnology-based materials, promoting faster more effective healing. research used an integrative literature review with databases such as PubMed, Scopus ScienceDirect, covering publications between 2019 2024. results highlight the use of Despite this, challenges remain, personalizing treatments adapting to different needs. combination methods emerging technologies has potential optimize care, accelerate tissue regeneration improve patients' quality life. study concludes integrated multidisciplinary approaches, combined new developments, are essential overcome barriers complex wounds.
Language: Английский
Citations
0Enhanced Cell Proliferation, Migration, and Fibroblast Differentiation with Electrospun PCL–Zinc Scaffolds Coated with Fibroblast-Derived ECM
ACS Omega, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 28, 2025
Despite tremendous improvement in the development of tissue-regenerating materials, a promising solution that provides an optimal environment remains to be accomplished. Here, we report composite nanofiber biomaterial scaffold as closely mimics extracellular matrix (ECM) improve cell viability, proliferation, and migration. Initially, composites polycaprolactone (PCL) zinc (Zn) metal were fabricated by using electrospinning. The resulting PCL–Zn (PZ) nanofibers effectively guided growth NIH3T3 fibroblasts for 7 days, forming fibroblast sheet. PZ fibers decellularized remove autologous allogenic cellular antigens while leaving intact ECM with structural functional components. PCL–Zn–ECM (PZE) showcased natural bonded surface, providing bioactive element interconnected fibers. reseeding demonstrated scaffold's excellent capacity direct support proliferation. Furthermore, vitro cytotoxicity analysis morphological staining confer biocompatibility. PZE presents which these scaffolds can further used various regenerative medicine applications including wound healing.
Language: Английский
Citations
0Eumelanin pigment release from photo-crosslinkable methacrylated gelatin-based cryogels: Exploring the physicochemical properties and antioxidant efficacy in wound healing
Biomaterials Advances, Journal Year: 2025, Volume and Issue: unknown, P. 214214 - 214214
Published: Jan. 1, 2025
Managing wounds in certain phases of the healing process still represents a big challenge. The oxidative stress, caused by reactive oxygen species (ROS), is one hallmarks controlling wound healing-related process. Multifunctional biomaterials with excellent biocompatibility, tuneable properties, and easy functionalization, may allow realizing suitable three-dimensional (3D) extracellular matrix (ECM)-mimicking structures, to efficiently control ROS levels. This might be promising strategy for severe wounds. Herein, photo-crosslinkable methacrylated gelatin (GelMA)-based spongy-like cryogels (from 5 20 % w/v) incorporating Eumelanin from Black Soldier Flies (BSF-Eumel, 0.5 1.0 mg/mL), pigment endowed marked antioxidant were developed. GelMA-based fabricated an easily handled scalable cryogelation followed ultraviolet (UV) photo-crosslinking. BSF-Eumel sub-micrometer particles embedded into passive permeation solution within polymeric network. addition resulted more hydrophilic porous exhibiting good stability prolonged release 14 days. Furthermore, GelMA/BSF-Eumel exhibited activity, confirmed powerful quenching effect on 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical (59 at mg/mL BSF-Eumel). Moreover, highest GelMA concentrations (10 accelerated human dermal fibroblasts-adult (HDF-a) migration, promoting closure 24 h. They also proved mitigate modulating production levels preventing superoxide dismutase (SOD) activity inhibition HDFs stimulated lipopolysaccharide (LPS), owing BSF-Eumel. Such remarkable outcomes make platform healing.
Language: Английский
Citations
0Advanced machine learning-driven characterization of new natural cellulosic Lablab purpureus fibers through PCA and K-means clustering techniques
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 306, P. 141589 - 141589
Published: March 2, 2025
Language: Английский
Citations
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