Environmental Science & Technology,
Journal Year:
2023,
Volume and Issue:
57(16), P. 6444 - 6454
Published: April 6, 2023
Antidepressants
are
one
of
the
most
commonly
prescribed
pharmaceuticals.
Although
they
have
been
frequently
detected
in
aquatic
environments
around
globe,
little
is
known
regarding
their
adverse
effects
on
humans
and
organisms.
Recently,
an
vitro
monoamine
transporter
inhibition
assay
was
developed
to
detect
transporter-inhibitory
activities
antidepressants
wastewater
Japan.
However,
it
unclear
which
were
responsible
for
wastewater.
Herein,
per
capita
consumption
32
antidepressants,
excretion
unchanged
parent
compounds,
water
consumption,
removal
rate
during
treatment
processes,
potency
values
from
used
prioritize
concern
effluent
England
In
both
countries,
sertraline
O-desmethylvenlafaxine
had
highest
contribution
inhibitory
against
human
serotonin
(hSERT)
zebrafish
SERT
(zSERT),
respectively.
It
found
that
inhibited
zSERT
more
strongly
than
hSERT.
The
Japan
higher
thresholds
abnormal
behavior
fish.
prioritized
this
study
provide
insight
into
launching
environmental
monitoring
ecotoxicological
studies
antidepressants.
Chemistry & Biodiversity,
Journal Year:
2023,
Volume and Issue:
20(8)
Published: July 3, 2023
The
most
significant
groupings
of
cold-blooded
creatures
are
the
fish
family.
It
is
crucial
to
recognize
and
categorize
species
since
various
seafood
diseases
decay
exhibit
different
symptoms.
Systems
based
on
enhanced
deep
learning
can
replace
area's
currently
cumbersome
sluggish
traditional
approaches.
Although
it
seems
straightforward,
classifying
images
a
complex
procedure.
In
addition,
scientific
study
population
distribution
geographic
patterns
important
for
advancing
field's
present
advancements.
goal
proposed
work
identify
best
performing
strategy
using
cutting-edge
computer
vision,
Chaotic
Oppositional
Based
Whale
Optimization
Algorithm
(CO-WOA),
data
mining
techniques.
Performance
comparisons
with
leading
models,
such
as
Convolutional
Neural
Networks
(CNN)
VGG-19,
made
confirm
applicability
suggested
method.
feature
extraction
approach
Proposed
Deep
Learning
Model
was
used
in
research,
yielding
accuracy
rates
100
%.
performance
also
compared
image
processing
models
an
98.48
%,
98.58
99.04
98.44
99.18
%
99.63
Networks,
ResNet150V2,
DenseNet,
Visual
Geometry
Group-19,
Inception
V3,
Xception.
Using
empirical
method
leveraging
artificial
neural
networks,
model
shown
be
model.
Frontiers in Public Health,
Journal Year:
2022,
Volume and Issue:
10
Published: Aug. 11, 2022
Aims
Antidepressants
have
aroused
wide
public
concern
due
to
their
widespread
presence
in
water
and
harm
human
health
environment.
This
study
was
designed
evaluate
the
contribution
of
wastewater
treatment
plants
(WWTPs)
antidepressants
surface
water.
Methods
Data
evaluated
by
analyzing
samples
collected
from
influent,
effluent,
upstream
downstream
WWTPs
on
rivers
interest
Hangzhou,
Zhejiang
Province,
China.
Besides,
also
assessed
impact
release
drinking
An
automatic
solid-phase
extraction
combined
with
ultra-high
performance
liquid
chromatography-tandem
triple
quadrupole
mass
spectrometry
(UPLC-MS/MS)
used
detect
antidepressants.
Results
The
most
abundant
compound
venlafaxine,
followed
citalopram,
sertraline,
fluvoxamine
concentrations
between
0.6
87
ng/L.
showed
maximum
at
effluent
outlets
WWTPs,
greater
were
found
than
Qiantang
River.
results
source
finished
that
detection
concentration
lower
limit
method.
Conclusions
less
identified.
Nevertheless,
these
compounds
hardly
removed
processes.
Thus,
risks
deserve
close
attention.
Journal of Animal Ecology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 26, 2024
Abstract
In
our
rapidly
changing
world,
understanding
how
species
respond
to
shifting
conditions
is
of
paramount
importance.
Pharmaceutical
pollutants
are
widespread
in
aquatic
ecosystems
globally,
yet
their
impacts
on
animal
behaviour,
life‐history
and
reproductive
allocation
remain
poorly
understood,
especially
the
context
intraspecific
variation
ecologically
important
traits
that
facilitate
species'
adaptive
capacities.
We
test
whether
a
pharmaceutical
pollutant,
fluoxetine
(Prozac),
disrupts
trade‐off
between
individual‐level
(co)variation
behavioural,
freshwater
fish.
exposed
progeny
wild‐caught
guppies
(
Poecilia
reticulata
)
three
field‐relevant
levels
(mean
measured
concentrations:
0,
31.5
316
ng/L)
for
5
years,
across
multiple
generations.
used
12
independent
laboratory
populations
repeatedly
quantified
activity
risk‐taking
behaviour
male
guppies,
capturing
both
mean
behaviours
within
individuals
exposure
treatments.
also
key
(body
condition,
coloration
gonopodium
size)
assessed
post‐copulatory
sperm
(sperm
vitality,
number
velocity)
known
be
under
strong
sexual
selection
polyandrous
species.
Intraspecific
these
was
analysed
using
comprehensive,
multivariate
statistical
approach.
Fluoxetine
had
dose‐specific
(mean)
effect
trait
guppies:
low
pollutant
altered
body
condition
increased
size,
but
reduced
velocity.
At
individual
level,
behavioural
plasticity
by
eroding
within‐individual
behaviour.
between‐individual
correlations
pace‐of‐life
syndrome
traits:
it
triggered
emergence
(e.g.
condition)
size
vitality),
collapsed
other
size).
Our
results
reveal
chronic
global
can
affect
phenotypic
at
population
levels,
even
alter
among
such
manner.
discuss
need
integrate
analyses
association
with
fully
understand
animals
human‐induced
environmental
change.
