Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Dec. 28, 2024
The
risk
of
infertility
is
progressively
escalating
over
the
years,
and
it
has
been
established
that
exposure
to
environmental
pollutants
closely
linked
infertility.
As
a
prevalent
pollutant
in
daily
life,
there
still
lack
substantial
evidence
on
association
between
volatile
organic
compounds
(VOCs)
risk.
This
study
aimed
examine
VOCs
female
United
States.
Participant
data
sets
from
three
cycles
(2013–2020)
were
collected
downloaded
National
Health
Nutrition
Examination
Survey
(NHANES),
including
demographics,
examination,
laboratory
questionnaire
data.
baseline
characteristics
included
population
evaluated,
weighted
quartile
logistic
regression
was
used
analyze
urinary
metabolites
(mVOCs)
levels
Further
exploration
relationship
mVOCs
conducted
by
using
35
25
as
cut-off
points
for
age
BMI
subgroup
analyses,
respectively.
Restricted
cubic
spline
(RCS)
employed
elucidate
nonlinear
Additionally,
Bayesian
kernel
machine
(BKMR)
model
with
20,000
iterations
applied
link
when
exposed
mixed
or
individual
mVOCs.
A
total
1082
women
aged
18
45
years
this
study,
133
group
949
control
group.
analysis
suggested
34MHA,
AMCC
DHBMA
significantly
higher
compared
(p
<
0.05).
Quartile
indicated
AAMA
(Q3),
(Q4),
CYMA
(Q3)
HPMMA
positively
associated
all
models
Subgroup
revealed
different
factors
among
various
subgroups,
consistently
showing
positive
correlation
two
subgroups
Furthermore,
observed
only
≥
kg/m2.
RCS
2MHA,
ATCA,
BMA,
BPMA,
CYMA,
2HPMA,
3HPMA
PGA
exhibited
linear
dose-response
relationships
>
0.05),
while
remaining
variables
showed
BKMR
demonstrated
an
increasing
trend
accumulation
co-exposure.
represented
34MHA
research.
However,
inherent
limitations
cross-sectional
design
necessitate
pursuit
additional
prospective
experimental
research
further
validate
The Science of The Total Environment,
Journal Year:
2024,
Volume and Issue:
925, P. 171742 - 171742
Published: March 15, 2024
No
study
has
examined
the
association
between
per-
and
polyfluoroalkyl
substances
(PFAS)
exposure
chronic
obstructive
pulmonary
disease
(COPD)
risk.
This
aims
to
explore
this
relationship.
enrolled
4541
individuals
who
had
unavailable
data
on
PFAS,
COPD,
covariates
from
NHANES
2007–2018.
Serum
PFAS
including
perfluorohexane
sulfonate
(PFHxS),
perfluorononanoic
acid
(PFNA),
perfluorooctanoic
(PFOA),
perfluorooctane
sulfonic
(PFOS)
were
analyzed,
because
of
high
detective
rates.
Considering
skew
distribution
levels,
natural
logarithm-transformed
(Ln-PFAS)
was
used.
Logistic
regression
analysis,
restricted
cubic
spline
(RCS),
weighted
quantile
sum
(WQS)
performed
single,
nonlinear,
mixed
effects.
A
mediating
analysis
used
evaluate
mediated
effects
albumin.
Individuals
with
COPD
higher
levels
PFHxS,
PFNA,
PFOA,
PFOS
compared
those
without
COPD.
Ln-PFNA
(OR
males:
1.92,
95
%
CI:1.31
2.80,
P:
<0.001;
OR
females:
1.07,
CI:
0.81
1.40,
0.636)
ln-PFOA
2.17,
CI:1.38
3.41,
1.49,
1.08
2.05,
0.016)
associated
risk
especially
in
males.
The
interaction
PFNA
sex
significant
(P
interaction:
<0.001).
RCS
curve
demonstrated
nonlinear
relationship
nonlinear:0.001),
ln-PFNA
nonlinear:0.045),
WQS
showed
correlated
males
(OR:
1.44,
CI:1.18
1.75,
Albumin
PFOA
(mediated
proportion:
−17.94
%).
concludes
are
linked
a
males,
serum
albumin
plays
role
Thess
findings
beneficial
for
prevention
Further
studies
required
potential
mechanisms.
Journal of Health Population and Nutrition,
Journal Year:
2025,
Volume and Issue:
44(1)
Published: Jan. 24, 2025
The
present
study
explored
the
association
between
biological
aging
(BA),
healthy
eating
index-2015
(HEI-2015)
and
non-alcoholic
fatty
liver
disease
(NAFLD)
in
general
population
of
United
States.
We
used
data
from
NHANES
database
2017-2018
years
to
conduct
study.
Weighted
multivariable
logistic
regression
analysis,
restricted
cubic
spline
(RCS),
subgroup
analysis
were
performed
analyze
BA
HEI-2015
with
prevalence
NAFLD
mediation
effect
was
also
discussed.
Additionally,
generalized
additive
model
conducted
investigate
ZJU
index,
BARD
score,
fibrosis
score.
There
a
total
2,421
individuals.
RCS
shown
that
positively
correlated
NAFLD,
while
negative
risk.
After
adjusting
for
interfering
factors,
compared
lowest
quartiles
HEI-2015,
odds
ratios
95%
confidence
intervals
across
(1.24
(0.84,
1.84),
2.07
(1.15,
3.73)
2.49
(1.16,
5.38))
(0.89
(0.66,
1.18),
0.87
(0.65,
1.16)
0.64
(0.46,
0.87)),
respectively.
linear
positive
score
However,
correlation
existed
Mediation
showed
could
be
mediated
weakened
by
HEI-2015.
gradually
increases
BA,
but
this
can
diet.
Frontiers in Medicine,
Journal Year:
2024,
Volume and Issue:
11
Published: Dec. 13, 2024
This
study
investigated
the
association
between
coronary
artery
calcification
(CAC)
and
triglyceride
glucose-body
mass
index
(TyG-BMI)
in
patients
receiving
maintenance
hemodialysis
(MHD).
BMC Public Health,
Journal Year:
2024,
Volume and Issue:
24(1)
Published: Oct. 22, 2024
Evidence
for
the
relationship
between
individual
and
combined
volatile
organic
compounds
(VOCs)
cardiovascular
disease
(CVD)
is
limited.
Besides,
mediating
role
of
biological
aging
(BA)
has
not
been
studied.
Therefore,
this
study
aimed
to
examine
association
VOCs
CVD
risk
explore
effects
BA.
