The Versatile Wayfinder: Prefrontal Contributions to Spatial Navigation

Trends in Cognitive Sciences, Journal Year: 2021, Volume and Issue: 25(6), P. 520 - 533

Published: March 20, 2021

Language: Английский

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The geometry of domain-general performance monitoring in the human medial frontal cortex

Science, Journal Year: 2022, Volume and Issue: 376(6593)

Published: May 5, 2022

Controlling behavior to flexibly achieve desired goals depends on the ability monitor one's own performance. It is unknown how performance monitoring can be both flexible, support different tasks, and specialized, perform each task well. We recorded single neurons in human medial frontal cortex while subjects performed two tasks that involve three types of cognitive conflict. Neurons encoding conflict probability, conflict, error one or were intermixed, forming a representational geometry simultaneously allowed specialization generalization. retrospectively served update internal estimates probability. Population representations compositional. These findings reveal evaluative signals abstract task-specific suggest neuronal mechanism for estimating control demand.

Language: Английский

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Perceptual reality monitoring: Neural mechanisms dissociating imagination from reality

Neuroscience & Biobehavioral Reviews, Journal Year: 2022, Volume and Issue: 135, P. 104557 - 104557

Published: Feb. 2, 2022

Language: Английский

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Depression and Anxiety During the COVID-19 Pandemic: Epidemiology, Mechanism, and Treatment

Neuroscience Bulletin, Journal Year: 2022, Volume and Issue: 39(4), P. 675 - 684

Published: Nov. 21, 2022

Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has had an adverse impact on the physical and mental health of public worldwide. In addition to illness in patients with COVID-19, isolated people general population have experienced problems due social distancing policies, mandatory lockdown, other psychosocial factors, prevalence depression anxiety significantly increased during pandemic. purpose this review is elucidate epidemiology, contributing pathogenesis anxiety. These findings indicate that physicians psychiatrists should pay more attention identify those a high risk for problems, such as females, younger people, unmarried low educational level. addition, researchers focus identifying neural neuroimmune mechanisms involved anxiety, assess intestinal microbiome effective biomarkers. We also provide overview various intervention methods, including pharmacological treatment, psychological therapy, physiotherapy, reference different populations guide development optimized methods.

Language: Английский

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Organization of the human cerebral cortex estimated within individuals: networks, global topography, and function

Journal of Neurophysiology, Journal Year: 2024, Volume and Issue: 131(6), P. 1014 - 1082

Published: March 15, 2024

The organization of cerebral networks was estimated within individuals with intensive, repeat sampling fMRI data. A hierarchical emerged in each individual that delineated first-, second-, and third-order cortical networks. Regions distinct association consistently exhibited side-by-side juxtapositions repeated across multiple zones, clear robust functional specialization among the embedded regions.

Language: Английский

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Frontal lobe syndromes

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 627 - 640

Published: July 16, 2024

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Violations of physical and psychological expectations in the human adult brain

Imaging Neuroscience, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Abstract After seeing one solid object apparently passing through another, or a person taking the long route to destination when shortcut was available, human adults classify those events as surprising. When tested on these in violation-of-expectation (VOE) experiments, infants look longer at same outcomes, relative similar but expected outcomes. What cognitive processes underlie judgments from adults, and perhaps infants' sustained attention events? As approach test this question, we used functional magnetic resonance imaging (fMRI) scan brains of (total N = 49, 22 female, mean age 26 years) while they viewed stimuli that were originally designed for physical psychological expectations infants. We examined non-mutually exclusive candidates underlying VOE effect, including domain-general processes, like visual prediction error curiosity, domain-specific with respect distinctively (objects are solid; agents behave rationally). Early regions did not distinguish between unexpected either domain. By contrast, multiple demand regions, involved goal-directed attention, responded more both domains, providing evidence mechanism VOE. Left supramarginal gyrus (LSMG) engaged during preferentially domain, error. Thus, adult brains, violations involve domain-specific, domain-general, though purely visual, computations.

Language: Английский

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Orthogonal neural encoding of targets and distractors supports multivariate cognitive control

Nature Human Behaviour, Journal Year: 2024, Volume and Issue: 8(5), P. 945 - 961

Published: March 8, 2024

Language: Английский

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Effects of single-session versus multi-session non-invasive brain stimulation on craving and consumption in individuals with drug addiction, eating disorders or obesity: A meta-analysis

Brain stimulation, Journal Year: 2018, Volume and Issue: 12(3), P. 606 - 618

Published: Dec. 27, 2018

Language: Английский

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Economic Choice as an Untangling of Options into Actions

Neuron, Journal Year: 2018, Volume and Issue: 99(3), P. 434 - 447

Published: Aug. 1, 2018

Language: Английский

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