Improvement of antibacterial activity of polysaccharides via chemical modification: A review

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 269, P. 132163 - 132163

Published: May 9, 2024

Language: Английский

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Multifunctional polypeptide-based hydrogel bio-adhesives with pro-healing activities and their working principles

Advances in Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 327, P. 103155 - 103155

Published: April 16, 2024

Language: Английский

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A Multifunctional Herb‐Derived Glycopeptide Hydrogel for Chronic Wound Healing

Small, Journal Year: 2024, Volume and Issue: unknown

Published: April 30, 2024

Chronic wounds constitute an increasingly prevalent global healthcare issue, characterized by recurring bacterial infections, pronounced oxidative stress, compromised functionality of immune cells, unrelenting inflammatory reactions, and deficits in angiogenesis. In response to these multifaceted challenges, the study introduced a stimulus-responsive glycopeptide hydrogel constructed oxidized Bletilla striata polysaccharide (OBSP), gallic acid-grafted ε-Polylysine (PLY-GA), paeoniflorin-loaded micelles (MIC@Pae), called OBPG&MP. The emulates structure glycoprotein fibers extracellular matrix (ECM), exhibiting exceptional injectability, self-healing, biocompatibility. It adapts responsively microenvironment chronic wounds, sequentially releasing therapeutic agents eradicate infection, neutralize reactive oxygen species (ROS), modulate macrophage polarization, suppress inflammation, encourage vascular regeneration ECM remodeling, playing critical role across inflammatory, proliferative, remodeling phases wound healing. Both vitro vivo studies confirmed efficacy OBPG&MP regulating enhancing skin tissue. This research supports vast potential for herb-derived multifunctional hydrogels tissue engineering regenerative medicine.

Language: Английский

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Design and optimization of ε-poly-l-lysine with specific functions for diverse applications

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 262, P. 129513 - 129513

Published: Jan. 22, 2024

Language: Английский

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Oxidized hyaluronic acid/ε-polylysine/quaternized chitosan hydrogel with shear thinning injectability and self-healing properties for full-time and multipurpose wound healing

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 293, P. 139347 - 139347

Published: Jan. 2, 2025

Language: Английский

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Construction and properties of bacterial cellulose/chitosan microgel films loaded with ε-polylysine and its application on Tilapia preservation

Food Packaging and Shelf Life, Journal Year: 2025, Volume and Issue: 47, P. 101433 - 101433

Published: Jan. 1, 2025

Language: Английский

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Fe₃O₄-Based Nanospheres with High Photothermal Conversion Efficiency for Dual-Effect and Mild Biofilm Eradication against Periodontitis

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 26, 2025

Periodontitis, a chronic inflammatory oral disease resulting from plaque biofilms, affects about 743 million individuals worldwide. However, the efficacy of current treatments is hampered by challenges in delivering antibiotics to recalcitrant biofilms and bacterial resistance, thereby impeding successful treatment infectious diseases. To address issues, an antibacterial photothermal material was designed, comprising spherical structure zinc oxide (ZnO) wrapped with triiron tetraoxide (Fe3O4). The outer layer adsorbed epsilon-polylysine (EPL) electrostatic action, ultimately leading fabrication Fe3O4/ZnO/EPL nanoparticles (FZE NPs). Fe3O4 core endowed efficient properties, facilitating dispersion dense which dramatically promoted adsorption penetration ZnO EPL into effectively kill bacteria vitro enhanced sterilization ability. Additionally, upon dissolution aqueous media, acts as positively charged antimicrobial peptide that adsorbs onto surface negatively membranes, modulating responses. In order ascertain FZE NPs, investigation conducted their effects against periodontitis-associated pathogen Porphyromonas gingivalis (P. gingivalis) vitro. Furthermore, antiperiodontitis potential NPs evaluated Sprague-Dawley (SD) rats ligamentous periodontitis. addition, toxicity evaluations indicated had acceptable biosafety profile vivo. summary, nanospheres NPs) represent promising therapeutic strategy for

Language: Английский

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Innovations and challenges in the production of prepared dishes based on central kitchen engineering: A review and future perspectives

Innovative Food Science & Emerging Technologies, Journal Year: 2023, Volume and Issue: 91, P. 103521 - 103521

Published: Nov. 26, 2023

Language: Английский

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Application of novel-assisted radio frequency technology to improve ready-to-eat foods quality: A critical review

Food Bioscience, Journal Year: 2024, Volume and Issue: 59, P. 104182 - 104182

Published: April 26, 2024

Language: Английский

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Composite antibacterial hydrogels based on two natural products pullulan and ε-poly-l-lysine for burn wound healing

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 277, P. 134208 - 134208

Published: July 26, 2024

Language: Английский

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