Recent Development of Implantable Chemical Sensors Utilizing Flexible and Biodegradable Materials for Biomedical Applications DOI
Hu Chen, Liu Wang, Shangbin Liu

et al.

ACS Nano, Journal Year: 2024, Volume and Issue: 18(5), P. 3969 - 3995

Published: Jan. 25, 2024

Implantable chemical sensors built with flexible and biodegradable materials exhibit immense potential for seamless integration biological systems by matching the mechanical properties of soft tissues eliminating device retraction procedures. Compared conventional hospital-based blood tests, implantable have capability to achieve real-time monitoring high accuracy important biomarkers such as metabolites, neurotransmitters, proteins, offering valuable insights clinical applications. These innovative could provide essential information preventive diagnosis effective intervention. To date, despite extensive research on bioresorbable electronics, development has faced several challenges related design, resulting in only a limited number successful accomplishments. This review highlights recent advancements based materials, encompassing their sensing strategies, geometric configurations. The following discussions focus demonstrated detection various objects including ions, small molecules, few examples macromolecules using and/or sensors. Finally, we will present current explore future directions.

Language: Английский

Multifunctional Photoelectrochemical Biosensor Based on ZnIn2S4/ZnS QDs@Au–Ag-Reversed Photocurrent of Cu-Metal–Organic Framework Coupled with CRISPR/Cas-12a-Shearing for Assay of Dual Targets DOI

Haotian Du,

Tengyue Yin,

Jianru Wang

et al.

Analytical Chemistry, Journal Year: 2023, Volume and Issue: 95(17), P. 7053 - 7061

Published: April 20, 2023

False positives and negatives in bioanalytical assays remain a persistent problem. Herein, multifunctional photoelectrochemical (PEC) biosensor based on ZnIn2S4 (ZIS)/ZnS quantum dots (QDs)@Au–Ag-reversed photocurrent of Cu-metal–organic framework (MOF) coupled with CRISPR/Cas-12a-shearing was innovatively developed for assay dual targets. First, Cu-MOF as good PEC material shows cathodic photocurrent. Then, numerous ZIS/ZnS QDs were assembled to the Au–Ag nanoparticles (NPs) prepare stable highly amplified signal probe, which can just match energy level Cu-MOFs realized polarity-reversed first time. As empty-core nanostructure NPs has high specific surface area low density, bimetallic nanocrystal much increase reaction rate improve redox efficiency. When target CEA-produced cDNA opened hairpin DNA (HP1 DNA) electrode, QDs@Au–Ag probe conjugated electrode via hybridization, achieving significantly reversed current CEA detection. Moreover, binding kanamycin/aptamer generated acDNA (activator), activate trans-cleavage activity CRISPR-CAS12a system ssDNA, so sheared caused obvious decrease kanamycin The newly displayed excellent properties MOF combined unique CRISPR-Cas12a achieve sensitive detection targets, open new sensing platform rapid accurate analysis multiple targets effectively avoid false results clinical testing.

Language: Английский

Citations

46
Spinel-type persistent luminescence nanoparticles: From mechanisms, compositions to applications DOI

Tianqi Zhao,

Renagul Abdurahman,

Ruxiangul Aiwaili

et al.

Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 488, P. 215171 - 215171

Published: April 29, 2023

Language: Английский

Citations

45
On the Road from Single-Atom Materials to Highly Sensitive Electrochemical Sensing and Biosensing DOI Open Access
Lei Jiao, Weiqing Xu, Yu Wu

et al.

Analytical Chemistry, Journal Year: 2023, Volume and Issue: 95(1), P. 433 - 443

Published: Jan. 10, 2023

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTOn the Road from Single-Atom Materials to Highly Sensitive Electrochemical Sensing and BiosensingLei JiaoLei JiaoKey Laboratory of Pesticide Chemical Biology Ministry Education, International Joint Research Center for Intelligent Biosensing Technology Health, College Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. ChinaInstitute Molecular Metrology, Chemistry Engineering, Qingdao 266071, ChinaMore by Lei JiaoView Biography, Weiqing XuWeiqing XuKey XuView Yu WuYu WuKey WuView Hengjia WangHengjia WangKey WangView Liuyong HuLiuyong HuHubei Engineering Optoelectronic New Energy Materials, Key Plasma Advanced School Science Wuhan Institute Technology, 430205, HuView Wenling GuWenling GuKey GuView Chengzhou Zhu*Chengzhou ZhuKey China*[email protected]More ZhuView Biographyhttps://orcid.org/0000-0003-0679-7965Cite this: Anal. Chem. 2023, 95, 1, 433–443Publication Date (Web):January 10, 2023Publication History Received19 April 2022Published online10 January 2023Published inissue 10 2023https://pubs.acs.org/doi/10.1021/acs.analchem.2c01722https://doi.org/10.1021/acs.analchem.2c01722review-articleACS PublicationsCopyright © 2023 American SocietyRequest reuse permissionsArticle Views2478Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are COUNTER-compliant sum full text article downloads since November 2008 (both PDF HTML) across all institutions individuals. These metrics regularly updated reflect usage leading up last few days.Citations number other articles citing this article, calculated Crossref daily. Find more information about citation counts.The Altmetric Attention Score is a quantitative measure attention that research has received online. Clicking on donut icon will load page at altmetric.com with additional details score social media presence given article. how calculated. Share Add toView InAdd Full Text ReferenceAdd Description ExportRISCitationCitation abstractCitation referencesMore Options onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Biotechnology,Electrochemical detection,Metals,Platinum,Sensors Get e-Alerts

Language: Английский

Citations

44
Dual function of magnetic nanocomposites-based SERS lateral flow strip for simultaneous detection of aflatoxin B1 and zearalenone DOI
Limei Yin,

Jianrong Cai,

Lixin Ma

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 446, P. 138817 - 138817

Published: Feb. 20, 2024

Language: Английский

Citations

31
Recent Development of Implantable Chemical Sensors Utilizing Flexible and Biodegradable Materials for Biomedical Applications DOI
Hu Chen, Liu Wang, Shangbin Liu

et al.

ACS Nano, Journal Year: 2024, Volume and Issue: 18(5), P. 3969 - 3995

Published: Jan. 25, 2024

Implantable chemical sensors built with flexible and biodegradable materials exhibit immense potential for seamless integration biological systems by matching the mechanical properties of soft tissues eliminating device retraction procedures. Compared conventional hospital-based blood tests, implantable have capability to achieve real-time monitoring high accuracy important biomarkers such as metabolites, neurotransmitters, proteins, offering valuable insights clinical applications. These innovative could provide essential information preventive diagnosis effective intervention. To date, despite extensive research on bioresorbable electronics, development has faced several challenges related design, resulting in only a limited number successful accomplishments. This review highlights recent advancements based materials, encompassing their sensing strategies, geometric configurations. The following discussions focus demonstrated detection various objects including ions, small molecules, few examples macromolecules using and/or sensors. Finally, we will present current explore future directions.

Language: Английский

Citations

29