Triple-shielded electrochemiluminescent aptasensor based on mesoporous silica film for the highly sensitive detection of aflatoxin B1 in wheat DOI

Silun Li,

Rundong Li, Xinyan Zhang

et al.

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: unknown, P. 137137 - 137137

Published: Dec. 1, 2024

Language: Английский

A trivalent aptasensor by using DNA tetrahedron as scaffold for label-free determination of antibiotics DOI
Tai Ye, Yimin Xu, Haohao Chen

et al.

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 251, P. 116127 - 116127

Published: Feb. 16, 2024

Language: Английский

Citations

13

DNA Tetrahedra as Functional Nanostructures: From Basic Principles to Applications DOI Creative Commons
Yu Ouyang, Pu Zhang, Itamar Willner

et al.

Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: 63(41)

Published: July 22, 2024

Abstract Self‐assembled supramolecular DNA tetrahedra composed of programmed sequence‐engineered complementary base‐paired strands represent elusive nanostructures having key contributions to the development and diverse applications nanotechnology. By appropriate engineering strands, tuneable sizes chemical functionalities were designed. Programmed for integrated into structures including sequence‐specific recognition (aptamers), catalytic DNAzymes, nanoparticles, proteins, or fluorophore. The article presents a comprehensive review addressing methods assemble characterize nanostructures, framework are discussed. Topics being addressed include application structurally functionalized nanostructure assembly optical electrochemical sensing platforms intracellular imaging modules. In addition, triggered reconfiguration dynamic networks circuits emulating biological transformations introduced. Moreover, functionalization frameworks with nanoparticles provides building units devices crystallization nanoparticle superlattices. Finally, in field nanomedicine addressed. These tetrahedra‐assisted permeation nanocarriers cells imaging, controlled drug release, active chemodynamic/photodynamic treatment target tissues, regenerative medicine.

Language: Английский

Citations

11

Ultrasensitive terahertz microfluidic biosensor integrated with tetrahedral DNA nanostructure for specific detection of live cancer cells DOI
Peng Shen, Yunyun Ji,

Xinmin Yue

et al.

Sensors and Actuators B Chemical, Journal Year: 2025, Volume and Issue: 428, P. 137252 - 137252

Published: Jan. 11, 2025

Language: Английский

Citations

1

Triple multivalent aptamers within DNA tetrahedron on reduced graphene oxide electrode: Unlocking enhanced sensitivity and accelerated reactions in electrochemical sensing DOI
Seung Joo Jang, Tae Hyun Kim

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 249, P. 116039 - 116039

Published: Jan. 14, 2024

Language: Английский

Citations

7

Construction of electrochemical and electrochemiluminescent dual-mode aptamer sensors based on ferrocene dual-functional signal probes for the sensitive detection of Alternariol DOI

Mingzhe Jiang,

Min Wang,

Wenjing Lai

et al.

Analytica Chimica Acta, Journal Year: 2023, Volume and Issue: 1272, P. 341476 - 341476

Published: June 8, 2023

Language: Английский

Citations

16

Dual-functional Nanomaterials Polyo-phenylenediamine and Ru–Au Complement Each Other to Construct an Electrochemical and Electrochemiluminescent Dual-Mode Aptamer Sensor for Sensitive Detection of Alternariol DOI

Mingzhe Jiang,

Min Wang,

Xuetong Song

et al.

Analytical Chemistry, Journal Year: 2023, Volume and Issue: 95(33), P. 12459 - 12469

Published: Aug. 11, 2023

To sensitively monitor trace amounts of alternariol (AOH) in fruits, a dual-mode aptamer sensor utilizing the dual-function nanomaterial PoPD/Ru–Au was developed. This provides both electrochemical (EC) and electrochemiluminescence (ECL) signals, which can greatly avoid potential false positive traditional single signal, thus enhancing accuracy reliability detection results. Polyo-phenylenediamine (PoPD), known for its favorable EC response, also assist ECL behavior Ru–Au. Furthermore, Ru–Au demonstrates excellent performance effectively activates K2S2O8 to amplify response PoPD. The complementary effect two final signal. Additionally, exhibits electrical conductivity, further signals. experimental results demonstrate that range AOH 0.01–100 ng/mL, while 0.001–100 exhibiting satisfactory linear relationship. Therefore, mutual verification be highly realized, purpose avoiding wrong achieved.

Language: Английский

Citations

16

Advances in enzyme-free nucleic acid amplification-based fluorescent biosensors for real-time imaging of DNA repair enzymes in living cells DOI
Qian Zhang,

Cong Su,

Jian‐Ge Qiu

et al.

Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 496, P. 215406 - 215406

Published: Aug. 29, 2023

Language: Английский

Citations

15

A Triple Signal Amplification Strategy for Accurate and Ultrasensitive miRNA-21 Detection DOI

Jiajun Zhan,

Futing Wang, Yujin Li

et al.

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(36), P. 14464 - 14470

Published: Aug. 26, 2024

A triple signal amplification strategy was integrated with a built-in double electrode and external energy storage device to fabricate novel self-powered biosensor for ultrasensitive detection of miRNA-21. Specifically, DNA tetrahedra haripin2-glucose oxidase are modified on the surface biocathode bioanode by catalytic hairpin assembly (CHA) achieve dual amplification. Moreover, is realized including an capacitor. Consequently, as-constructed demonstrates low limit 0.06 fM toward miRNA-21 assay within range 0.1 10 pM. This study presents practical sensitive approach timely cancer detection.

Language: Английский

Citations

5

Multipedal DNA Walker: Engineering Strategy, Biosensing Application and Future Perspectives DOI
Xiuyuan Yao,

Linyao Wang,

Jie Luo

et al.

ACS Sensors, Journal Year: 2024, Volume and Issue: 9(11), P. 5748 - 5762

Published: Oct. 18, 2024

With the continuous development of DNA nanotechnology, walkers have attracted increased attention because their autonomous and progressive walking along predesigned tracks. Compared with traditional walkers, emerged multipedal showed special charm sustainable capability, higher reaction efficiency, expanded region, improved amplification capability. Consequently, developed rapidly shown potential in biosensing applications. Hence, this review, we make a comprehensive representation engineering strategy which focused on design multiple strands as well construction tracks driving forces. Meanwhile, application biosensors has been thoroughly described according to type signal readout. By illustrating some representative works, also summarized merits challenges walker-based offered deep discussion latest progress future.

Language: Английский

Citations

5

Self-assembled methodologies for the construction of DNA nanostructures and biological applications DOI
Rui Ye, Yuqi Wang, Yan Liu

et al.

Biomaterials Science, Journal Year: 2024, Volume and Issue: 12(15), P. 3712 - 3724

Published: Jan. 1, 2024

Overview of the methodologies and applications DNA self-assembly, including conventional strategy based on Watson–Crick base-pairing, hybrid assembly mediated by functional elements their in biological fields.

Language: Английский

Citations

4