Ultrasonics, Journal Year: 2022, Volume and Issue: 125, P. 106798 - 106798
Published: June 30, 2022
Language: Английский
Journal of Applied Clinical Medical Physics, Journal Year: 2022, Volume and Issue: 23(5)
Published: April 12, 2022
Agar gels were previously proven capable of accurately replicating the acoustical and thermal properties real tissue widely used for construction tissue-mimicking phantoms (TMPs) focused ultrasound (FUS) applications. Given current popularity magnetic resonance-guided FUS (MRgFUS), we have investigated MR relaxation times T1 T2 different mixtures agar-based phantoms. Nine TMPs constructed containing agar as gelling agent various concentrations silicon dioxide evaporated milk. An phantom doped with wood powder was also evaluated. A series images acquired in a 1.5 T scanner mapping. predominantly affected by varying concentrations. trend toward decreasing an increasing concentration milk observed. The addition decreased both pure gels. proposed great potential use continuously emerging MRgFUS technology. several body tissues can be mimicked adjusting ingredients, thus enabling more accurate realistic studies.
Language: Английский
Citations
26
Bioengineering, Journal Year: 2024, Volume and Issue: 11(6), P. 620 - 620
Published: June 18, 2024
Medical imaging has allowed for significant advancements in the field of ultrasound procedures over years. However, each modality exhibits distinct limitations that differently affect their accuracy. It is imperative to ensure quality identify and eliminate these limitations. To achieve this, a tissue-mimicking material (TMM) phantom utilised validation. This study aims perform systematic analysis materials used creating phantoms. We reviewed 234 studies on use TMM phantoms were published from 2013 2023 two research databases. Our focus was discussed TMMs’ properties fabrication ultrasound, elastography, flow The screening process led selection 16 out include analysis. categorised into three groups based solvent used; group offers broad range physical properties. water-based most closely aligns with ultrasound. provides important information about also compared real human tissues found PVA matches best.
Language: Английский
Citations
5
Medical Physics, Journal Year: 2023, Volume and Issue: 50(10), P. 5956 - 5968
Published: May 24, 2023
The persistent development of focused ultrasound (FUS) thermal therapy in the context oncology creates need for tissue-mimicking tumor phantom models early-stage experimentation and evaluation relevant systems protocols.This study presents a tumor-bearing tissue model testing magnetic resonance imaging (MRI)-guided FUS (MRgFUS) ablation protocols equipment based on MR thermometry.Normal was mimicked by pure agar gel, while simulator differentiated from surrounding material including silicon dioxide. characterized terms acoustic, thermal, MRI properties. US, MRI, computed tomography (CT) images were acquired to assess contrast between two compartments. phantom's response heating investigated performing high power sonications with 2.4 MHz single element spherically ultrasonic transducer 3T scanner.The estimated properties fall within range literature-reported values soft tissues. inclusion dioxide offered excellent visualization CT. thermometry revealed temperature elevations levels clear evidence larger heat accumulation owing dioxide.Overall, findings suggest that proposed constitutes simple inexpensive tool preclinical MRgFUS studies, potentially other image-guided applications upon minimal modifications.
Language: Английский
Citations
11
IEEE Reviews in Biomedical Engineering, Journal Year: 2024, Volume and Issue: 18, P. 93 - 112
Published: June 6, 2024
The advent of flexible, compact, energy-efficient, robust, and user-friendly wearables has significantly impacted the market growth, with an estimated value 61.30 billion USD in 2022. Wearable sensors have revolutionized in-home health monitoring by warranting continuous measurements vital parameters. Ultrasound is used to non-invasively, safely, continuously record next generation smart ultrasonic devices for healthcare integrates microelectronics stretchable patches body-conformable devices. They offer not only wearability, user comfort, but also higher tracking accuracy immediate changes cardiovascular Moreover, due fixed adhesion skin, errors derived from probe placement or patient movement are mitigated, even though at correct anatomical location still critical requires a user's skill knowledge. In this review, steps required bring wearable systems into medical (technologies, device development, signal-processing, in-lab validation, and, finally, clinical validation) discussed. vascular ultrasound its future research directions many possibilities modernizing assessment quality personalized care home monitoring.
Language: Английский
Citations
4
Ultrasonics, Journal Year: 2021, Volume and Issue: 119, P. 106600 - 106600
Published: Oct. 4, 2021
Language: Английский
Citations
25
International Journal of Medical Robotics and Computer Assisted Surgery, Journal Year: 2022, Volume and Issue: 18(2)
Published: Jan. 7, 2022
A robotic system for Magnetic Resonance guided Focussed Ultrasound (MRgFUS) therapy of tumours in the breast, bone, thyroid, and abdomen was developed.A special C-shaped structure designed to be attached table conventional magnetic resonance imaging (MRI) systems carrying 4 computer-controlled motion stages dedicated positioning a 2.75 MHz spherically focussed transducer relative patient placed supine position. The developed evaluated its MRI compatibility heating abilities agar-based phantoms freshly excised tissue.Compatibility with clinical high-field scanner demonstrated. FUS phantom successfully monitored by thermometry without any evidence magnetically induced phenomena. Cigar-shaped discrete lesions well-defined areas overlapping were inflicted tissue movement along grid patterns.The MRgFUS proven safe efficient ex-vivo feasibility studies.
Language: Английский
Citations
18
Physica Medica, Journal Year: 2025, Volume and Issue: 131, P. 104932 - 104932
Published: Feb. 11, 2025
Language: Английский
Citations
0
Journal of Medical Physics, Journal Year: 2025, Volume and Issue: 50(1), P. 38 - 45
Published: Jan. 1, 2025
This study presents the outcomes of a series magnetic resonance imaging (MRI)-guided focused ultrasound (MRgFUS) sonications performed on an anatomically accurate head phantom with embedded tumor simulator to evaluate effectiveness partial and complete ablation obstruction from thin polymer skull mimics. The was subjected single grid using single-element concave transducer integrated MRI-compatible (FUS) robotic system. All experiments were carried out in high-field MRI scanner utilizing proton frequency thermometry T2-weighted (T2-W) turbo spin echo (TSE) induced thermal effects. FUS transmission through 1-mm thick three-dimensional-printed mimics compared unobstructed sonication circular aperture model. T2-W TSE demonstrated sharp contrast between hyperintense lesions. Complete coverage achieved robotic-assisted without mimic, as well resin mimic intervening beam. With lowest attenuation among tested polymers, resulted approximately 20% reduction focal temperature change sonication, yet still facilitated beam focusing, raising ablative levels. provides preliminary evidence for potential application biocompatible implant temporarily replace portion facilitating MRgFUS inoperable tumors transducer. tumor-embedded proven effective testing oncological protocols equipment.
Language: Английский
Citations
0
Radiological Physics and Technology, Journal Year: 2025, Volume and Issue: unknown
Published: March 23, 2025
Language: Английский
Citations
0
Journal of Ultrasound, Journal Year: 2023, Volume and Issue: 27(2), P. 263 - 274
Published: July 30, 2023
Abstract Purpose The study aims to provide insights on the practicality of using single-element transducers for transcranial Focused Ultrasound (tFUS) thermal applications. Methods FUS sonications were performed through skull phantoms embedding agar-based tissue mimicking gels a 1 MHz spherically focused transducer. 3D printed with Acrylonitrile Butadiene Styrene (ABS) and Resin thermoplastics having exact bone geometry healthy volunteer. temperature field distribution during after heating was monitored in 3 T Magnetic Resonance Imaging (MRI) scanner MR thermometry. effect skull’s thickness intracranial investigated. Results A single sonication at focal acoustic intensities close 1580 W/cm 2 60 s free heated up agar phantom ablative temperatures reaching about 90 °C (baseline 37 °C). ABS strongly blocked ultrasonic waves, resulting zero increase within phantom. Considerable achieved skull, but it remained hyperthermia levels. Conversely, tFUS mm showed enhanced penetration heating, 70 °C. Conclusions demonstrated poorer performance terms compared owing its higher attenuation porosity. thin provided an efficient window delivering deep areas. results such studies could be particularly useful accelerating establishment wider range
Language: Английский
Citations
8