Appropriateness for SARS-CoV-2 vaccination for otolaryngologist and head and neck surgeons in case of pregnancy, breastfeeding, or childbearing potential: Yo-IFOS and CEORL-HNS joint clinical consensus statement DOI Creative Commons
Alberto Maria Saibene, Fabiana Allevi, Tareck Ayad

et al.

European Archives of Oto-Rhino-Laryngology, Journal Year: 2021, Volume and Issue: 278(10), P. 4091 - 4099

Published: April 15, 2021

SARS-CoV-2 vaccines are a key step in fighting the pandemic. Nevertheless, their rapid development did not allow for testing among specific population subgroups such as pregnant and breastfeeding women, or elaborating guidelines healthcare personnel working high infection risk specialties, otolaryngology (ORL). This clinical consensus statement (CCS) aims to offer guidance vaccination this high-risk based on best evidence available. A multidisciplinary international panel of 33 specialists judged statements through two-round modified Delphi method survey. Statements were designed encompass following topics: SARS-Cov-2 use protective equipment ORL; respective risks mother/child dyad; counseling pregnant, breastfeeding, fertile workers (PBFHW). All ORL PBFHW considered target audience. Of 13 statements, 7 reached strong consensus, 2 no near-consensus. According with otorhinolaryngologists-head neck surgeons who childbearing potential should have opportunity receive vaccination. Moreover, personal (PPE) still be used even after Until prospective evaluations these topics available, ORL-HNS must specialty. While PPE remains pivotal, allowed access provided they up-to-date information.

Language: Английский

Pregnant women’s perceptions of the COVID-19 vaccine: A French survey DOI Creative Commons
Charles Egloff, Camille Couffignal,

Anne Cordier

et al.

PLoS ONE, Journal Year: 2022, Volume and Issue: 17(2), P. e0263512 - e0263512

Published: Feb. 7, 2022

Introduction Pregnant women are at increased risk for COVID-19, and COVID-19 vaccine is the most promising solution to overcome current pandemic. This study was conducted evaluate pregnant women’s perceptions acceptance of vaccination. Materials & methods A cross-sectional from February 18 April 5 2021. An anonymous survey distributed in 7 French obstetrics departments all before a prenatal visit. All attending follow-up consultation were asked participate study. web available through QR code participants whether or not they would agree be vaccinated against SARS-CoV-2, why. The questionnaire included questions on patients’ demographics their knowledge vaccines. Results Of 664 who completed questionnaire, 29.5% (95% CI 27.7; 31.3) indicated COVID-19. main reason agreeing being more afraid potential side effects SARS-CoV-2 fetus than Factors influencing vaccination were: slightly older, multiparity, having discussed it with caregiver influenza vaccine. Discussion Nearly one-third this population willing vaccinated. In addition studies establishing fetal safety, public health agencies healthcare professionals should provide accurate information about safety

Language: Английский

Citations

63
Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and infancy DOI Creative Commons
Mary Prahl, Yarden Golan, Arianna G. Cassidy

et al.

Nature Communications, Journal Year: 2022, Volume and Issue: 13(1)

Published: July 30, 2022

Studies are needed to evaluate the safety and effectiveness of mRNA SARS-CoV-2 vaccination during pregnancy, levels protection provided their newborns through placental transfer antibodies. Here, we transplacental vaccine products functional anti-SARS-CoV-2 antibodies pregnancy early infancy in a cohort 20 individuals vaccinated late pregnancy. We find no evidence maternal blood, placenta tissue, or cord blood at delivery. However, time-dependent efficient IgG neutralizing neonate that persists infancy. Additionally, using phage immunoprecipitation sequencing, vaccine-specific signature Spike protein epitope binding is transplacentally transferred Timing critical ensure protective

Language: Английский

Citations

50
Worldwide beliefs among pregnant women on SARS-CoV-2 vaccine: a systematic review DOI Open Access
Luigi Carbone, Raffaella Di Girolamo, Ilenia Mappa

et al.

European Journal of Obstetrics & Gynecology and Reproductive Biology, Journal Year: 2021, Volume and Issue: 268, P. 144 - 164

Published: Dec. 7, 2021

Language: Английский

Citations

38
COVID‐19 and novel mRNA vaccines in pregnancy: an updated literature review DOI Open Access
E.P. Joubert,

AC Kekeh,

CN Amin

et al.

BJOG An International Journal of Obstetrics & Gynaecology, Journal Year: 2021, Volume and Issue: 129(1), P. 21 - 28

Published: Oct. 15, 2021

The novel coronavirus, SARS-CoV-2, or COVID-19, has affected the world on a pandemic scale resulting in catastrophic outcomes and deaths. Currently, there is limited safety data specific to mRNA vaccine use pregnant lactating individuals potential risks individual fetus are unknown. We report an updated literature review of current information evidence available aid decision whether vaccinate against COVID-19 currently being made by their healthcare providers so that they able make well-informed recommendation decision.

Language: Английский

Citations

37
Coronavirus disease 2019 (Covid‐19) vaccination recommendations in special populations and patients with existing comorbidities DOI Open Access
Zeinab Mohseni Afshar, Arefeh Babazadeh, Alireza Janbakhsh

et al.

Reviews in Medical Virology, Journal Year: 2021, Volume and Issue: 32(3)

Published: Oct. 22, 2021

Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a crucial step in ending the current worldwide pandemic. However, several particularly vulnerable groups population were not included sufficient numbers disease 2019 (Covid-19) vaccine trials. Therefore, as science advances, advice for vaccinating these special populations Covid-19 will continue to evolve. This focused review provides latest recommendations and considerations (i.e., patients with rheumatologic autoimmune disorders, cancer, transplant recipients, chronic liver diseases, end-stage renal disease, neurologic psychiatric diabetes mellitus, obesity, cardiovascular obstructive pulmonary human immunodeficiency virus, smokers, pregnant breastfeeding women, elderly, children, allergic reactions) using currently available research evidence.

Language: Английский

Citations

37
Comparison of Vaccine Acceptance Between COVID-19 and Seasonal Influenza Among Women in China: A National Online Survey Based on Health Belief Model DOI Creative Commons
Liyuan Tao,

Ruitong Wang,

Jue Liu

et al.

Frontiers in Medicine, Journal Year: 2021, Volume and Issue: 8

Published: June 4, 2021

Background: Influenza could circulate in parallel with COVID-19. Studies focusing on the comparison of vaccine acceptance between COVID-19 and seasonal influenza are lacking. The aim study was to assess compare among reproductive women China, order better understand address factors associated provide guidance for targeted measures promote vaccination. Methods: A national anonymous cross-sectional survey aged 18–49 years China conducted online based health belief model, a model widely used evaluate beliefs. Sociodemographic characteristics, status, knowledge, attitude, beliefs related infection vaccination were retrieved. Pearson's χ 2 test by mentioned above. Multivariable logistic regression adjusted associations acceptance. Paired t -test scores vaccinations. Results: rate 90.3% (95% CI 89.2–91.3%), which significantly higher than (85.5%, 95% CI: 84.2–86.7%). both had trends decrease age (all p < 0.05). Living western region, young age, high level knowledge disease vaccines, perceived susceptibility, cues action, low barriers positively 0.05), while history additionally ( Conclusions: Our findings suggest that tailored public needed improve women's COVID-19, influenza, vaccines alleviate hesitancy expand uptake.

Language: Английский

Citations

36
COVID-19 Vaccine Considerations during Pregnancy and Lactation DOI
Dean A. Blumberg, Aparna Sridhar, Satyan Lakshminrusimha

et al.

American Journal of Perinatology, Journal Year: 2021, Volume and Issue: 38(06), P. 523 - 528

Published: May 1, 2021

COVID-19 vaccines have been developed with unprecedented rapidity, deliver the vaccine antigen in a completely different manner than all previous widespread use, and are made available outside of routine Food Drug Administration (FDA) approval process. Therefore, it is understandable that there uncertainty about safety their administration during pregnancy lactation, both among clinicians those who pregnant or lactating. In this commentary, we review limited data as well theoretical considerations concerning vaccination lactation. Finally, discuss guidance situation our perspective context disease severity transmission.

Language: Английский

Citations

33
Perceptions and Attitudes toward COVID-19 Vaccination among Pregnant and Postpartum Individuals DOI
Molly Siegel, Mario I. Lumbreras-Márquez, Kaitlyn E. James

et al.

American Journal of Perinatology, Journal Year: 2022, Volume and Issue: 29(14), P. 1489 - 1495

Published: June 16, 2022

This study aimed to characterize attitudes toward novel coronavirus disease 2019 (COVID-19) vaccination and evaluate factors associated with vaccine uptake among pregnant individuals.An anonymous survey was distributed a convenience sample of individuals receiving prenatal care at two large urban academic hospitals in single health network Massachusetts. Individual demographic variables were included the along questions assessing COVID-19 pregnancy. Data analyzed using parametric or nonparametric tests when appropriate, odds ratios (OR) calculated via univariable logistic regression.There 684 surveys distributed, 477 postpartum completed survey, for response rate 69.7%. Overall, 233 (49.3%) had received scheduled receive vaccine. Age, White race, non-Hispanic Latinx ethnicity, working from home, typical receipt influenza vaccination. Further, 276 respondents (58.4%) reported that their provider recommended pregnancy; these participants more likely have (OR = 5.82, 95% confidence interval [CI]: 3.68-9.26, p < 0.005). Vaccinated less be worried about effects on themselves 0.18, CI: 0.12-0.27, 0.005) developing babies 0.17, 0.11-0.26, Unvaccinated report it is easy schedule 0.56, 0.34-0.93, 0.02), travel 0.19, 0.10-0.36, 0.005), miss work 0.30, 0.18-0.48, 0.005).Strategies are needed improve patient education regarding side safety Policy changes should focus making feasible patients without loss pay get vaccinated.· There racial ethnic disparities vaccination.. · concerned growing babies.. cited scheduling-related barriers vaccination, indicating areas advocacy..

Language: Английский

Citations

28
Evaluation of Transplacental Antibody Transfer in SARS-CoV-2-Immunized Pregnant Women DOI Creative Commons
Ching‐Ju Shen,

Yi-Chen Fu,

Yen-Pin Lin

et al.

Vaccines, Journal Year: 2022, Volume and Issue: 10(1), P. 101 - 101

Published: Jan. 10, 2022

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy could result in adverse perinatal outcome. Clinical data on the assessment of immune response vaccinated pregnant women and subsequent transplacental antibody transfer are quite limited. Objective: To assess maternal neonatal neutralizing levels against both wildtype Delta (B.1.617.2) variants after mRNA vaccination. Study Design: This cohort study was conducted 29 who were at least one dose Moderna (mRNA-1273) vaccine. Both (wildtype variant) S1 receptor binding domain IgG evaluated cord blood day delivery. Results: Superiority level significant fully compared with one-dose group (maternal sera, median, 97.46%; 97.37% versus 4.01%; 1.44%). No difference noted relation to interval second immunization delivery two-dose (95.99% 0–2 weeks, 97.45% 2–4 97.48% 4–8 97.72% 8–10 weeks). The most pronounced reduction observed for variant. full-vaccinated not influenced by pertussis Conclusion: underscore importance full vaccination support recommendation COVID-19 women. lower vaccine-induced antibodies variant indicates insufficient protection mother newborn highlights need development effective vaccine strategies.

Language: Английский

Citations

27
ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy DOI Open Access
Gilbert Donders, Švitrigailė Grincevičienė, Kai Haldre

et al.

Journal of Clinical Medicine, Journal Year: 2021, Volume and Issue: 10(13), P. 2902 - 2902

Published: June 29, 2021

Sars-CoV-2 infection poses particular problems in pregnancy, as the more frequently causes severe complications than unaffected pregnant women or nonpregnant with SARS-CoV-2 infection. Now that vaccination is available and rapidly being implemented worldwide, question arises whether should be vaccinated, if so, they receive priority.Available scientific data guidelines about against were collected by Guideline Committee of International Society Infectious Diseases Obstetrics Gynecology (ISIDOG) analyzed, discussed summarized for healthcare workers caring women. Concluding statements graded according to Oxford evidence-based medicine grading system.There evidence consider pregnancy a risk factor serious COVID-19 infection, even absence additional factors, such hypertension, diabetes obesity which increase these risks pregnancy. Currently slightly favor mRNA-based vaccines above vector-based during breastfeeding, until safety become available.ISIDOG advises policy makers societies prioritize mRNA further information becomes available.

Language: Английский

Citations

28