Effect of Ramadan intermittent fasting on inflammatory markers, disease severity, depression, and quality of life in patients with inflammatory bowel diseases: A prospective cohort study DOI Creative Commons
Mohamed Negm, Ahmed Bahaa, Ahmed Farrag

et al.

BMC Gastroenterology, Journal Year: 2022, Volume and Issue: 22(1)

Published: April 24, 2022

Intermittent fasting (IF) during the month of Ramadan is part religious rituals Muslims. The effect intermittent on disease activity in inflammatory bowel diseases (IBD) still unknown. This first study to assess IF markers patients diagnosed with IBD. effects clinical activity, quality life, and levels depression were also assessed.Patients ulcerative colitis (UC) or Crohn's (CD) who intended observe recruited. following assessed immediately before at end Ramadan: Serum CRP stool calprotectin, partial Mayo score, Harvey Bradshaw index (HBI), Simple IBD questionnaire (SIBDQ), Hamilton scale questionnaire.80 recruited (60 UC, 20 CD). calprotectin did not show a significant change vs after (median 0.53 0.50, P value = 0.27, Calprotectin 163 218 respectively, 0.62). score showed rise 1 fasting, mean: 1.79 2.33 0.02). Harvey-Bradshaw 4 5, 0.4). Multiple linear regression revealed that older age higher baseline associated (P 0.02 0.01, respectively). No was detected SIBDQ scores.In worsening parameters, more pronounced those levels. However, an adverse objective (CRP calprotectin).

Language: Английский

Role of Secondary Plant Metabolites on Enteric Methane Mitigation in Ruminants DOI Creative Commons
Juan Carlos Kú-Vera, Rafael Jiménez-Ocampo, Sara S. Valencia-Salazar

et al.

Frontiers in Veterinary Science, Journal Year: 2020, Volume and Issue: 7

Published: Aug. 27, 2020

The rumen microbiome plays a fundamental role in all ruminant species, it is involved health, nutrient utilization, detoxification, and methane emissions. Methane greenhouse gas which eructated large volumes by ruminants grazing extensive grasslands the tropical regions of world. Enteric largest contributor to emissions gases originating from animal agriculture. A variety plants containing secondary metabolites [essential oils (terpenoids), tannins, saponins, flavonoids] have been evaluated as cattle feedstuffs changes volatile fatty acid proportions synthesis assessed. Alterations may lead diversity, composition, structure methanogen community. Legumes condensed tannins such Leucaena leucocephala shown good mitigating effect when fed at levels up 30-35% ration dry matter result on bacteria methanogens. It has that saponins disrupt membrane protozoa, thus decreasing numbers both protozoa methanogenic archaea. Trials carried out with housed respiration chambers demonstrated enteric mitigation sheep legumes Enterolobium cyclocarpum Samanea saman contain saponins. Essential are constituents terpenoid or non-terpenoid origin impair energy metabolism archaea reductions 26% ruminants. There emerging evidence showing potential flavonoids compounds, but more work required vivo confirm preliminary findings. From information hereby presented, clear plant can be rational approach modulate modify its function, some species microbes improve protein fiber degradation reduce feed loss species.

Language: Английский

Citations

177

Effects of intermittent fasting and energy-restricted diets on lipid profile: A systematic review and meta-analysis DOI

Haiyan Meng,

Lei Zhu, Hamed Kord‐Varkaneh

et al.

Nutrition, Journal Year: 2020, Volume and Issue: 77, P. 110801 - 110801

Published: March 12, 2020

Language: Английский

Citations

117

Effect of diurnal fasting on sleep during Ramadan: a systematic review and meta-analysis DOI
MoezAlIslam E. Faris, Haitham Jahrami,

Fatema A. Alhayki

et al.

Sleep And Breathing, Journal Year: 2019, Volume and Issue: 24(2), P. 771 - 782

Published: Dec. 12, 2019

Language: Английский

Citations

113

Intermittent Fasting and Metabolic Health: From Religious Fast to Time‐Restricted Feeding DOI Open Access
Kristin K. Hoddy, Kara L. Marlatt, Hatice Çetinkaya

et al.

Obesity, Journal Year: 2020, Volume and Issue: 28(S1)

Published: July 1, 2020

Over the past 10 to 15 years, intermittent fasting has emerged as an unconventional approach reduce body weight and improve metabolic health beyond simple calorie restriction. In this review, we summarize findings related Ramadan Sunnah fasting. We then discuss role of caloric restriction not only intervention for control, but importantly, a strategy healthy aging longevity. Finally, review four most common (IF) strategies used date management cardiometabolic health. Weight loss is after IF does appear be different than daily when compared directly. may also provide additional benefit, such insulin sensitization, that independent from loss. While no specific regimen stands out superior at time, there indeed heterogeneity in responses these diets. This suggests one dietary ideally suited every individual. Future studies should consider tailoring prescriptions, including IF, based on advanced phenotyping genotyping prior diet initiation.

Language: Английский

Citations

103

Remodeling of the gut microbiome during Ramadan-associated intermittent fasting DOI Creative Commons
Junhong Su, Yueying Wang, Xiaofang Zhang

et al.

American Journal of Clinical Nutrition, Journal Year: 2020, Volume and Issue: 113(5), P. 1332 - 1342

Published: Nov. 25, 2020

Intermittent fasting is a popular dietary intervention with perceived relatively easy compliance and linked to various health benefits, including weight loss improvement in blood glucose concentrations. The mechanistic explanations underlying the beneficial effects of intermittent remain largely obscure but may involve alterations gut microbiota.We sought establish 1 mo on microbiome.We took advantage being voluntarily observed during Islamic faith-associated Ramadan sampled feces blood, as well collected longitudinal physiologic data 2 cohorts, different years. fecal microbiome was determined by 16S sequencing. Results were contrasted age- body weight-matched controls correlated parameters (e.g., mass calorie intake).We that Ramadan-associated increased diversity specifically associated upregulation Clostridiales order-derived Lachnospiraceae [no 24.6 ± 13.67 compared 39.7 15.9 relative abundance (%); linear discriminant analysis = 4.9, P < 0.001 coupled effect size measurements] Ruminococcaceae 13.4 6.9 23.2 12.9 4.7, bacterial families. Microbiome composition returned baseline upon cessation feeding. Furthermore, changes concentrations mirrored fasting-provoked parameters.Intermittent provokes substantial remodeling microbiome. butyric acid-producing provides an obvious possible explanation for fasting.

Language: Английский

Citations

102

A systematic review, meta-analysis, and meta-regression of the impact of diurnal intermittent fasting during Ramadan on body weight in healthy subjects aged 16 years and above DOI
Haitham Jahrami, Joud Zanabili, Cain C. T. Clark

et al.

European Journal of Nutrition, Journal Year: 2020, Volume and Issue: 59(6), P. 2291 - 2316

Published: March 10, 2020

Language: Английский

Citations

88

Effect of diurnal intermittent fasting during Ramadan on ghrelin, leptin, melatonin, and cortisol levels among overweight and obese subjects: A prospective observational study DOI Creative Commons
Natheer Al‐Rawi, Mohamed Madkour, Haitham Jahrami

et al.

PLoS ONE, Journal Year: 2020, Volume and Issue: 15(8), P. e0237922 - e0237922

Published: Aug. 26, 2020

Background Levels of cortisol, melatonin, ghrelin, and leptin are highly correlated with circadian rhythmicity. The levels these hormones affected by sleep, feeding, general behaviors, fluctuate light dark cycles. During the fasting month Ramadan, a shift to nighttime eating is expected affect rhythm and, subsequently, leptin. present study aimed examine effect diurnal intermittent (DIF) during Ramadan on daytime leptin, cortisol in group overweight obese subjects, determine how anthropometric, dietary, lifestyle changes correlate hormonal changes. Methods Fifty-seven male (40) female (17) subjects were enrolled this study. Anthropometric measurements, dietary intake, sleep duration, serum salivary assessed one week before start after 28 days at fixed times day (11:00 am-1:00 pm). Results At end significantly (P<0.001) decreased, while did not change compared pre-fasting state. Conclusions DIF altered Further, sex anthropometric variables most impacting factors tested four hormones. Further studies needed assess DIF's impact rhythmicity people.

Language: Английский

Citations

86

A systematic review, meta-analysis, and meta-regression of the impact of diurnal intermittent fasting during Ramadan on glucometabolic markers in healthy subjects DOI
MoezAlIslam E. Faris, Haitham Jahrami, Ahmed S. BaHammam

et al.

Diabetes Research and Clinical Practice, Journal Year: 2020, Volume and Issue: 165, P. 108226 - 108226

Published: May 21, 2020

Language: Английский

Citations

78

Plant Extracts Rich in Polyphenols as Potent Modulators in the Growth of Probiotic and Pathogenic Intestinal Microorganisms DOI Creative Commons
Milica Milutinović, Suzana Dimitrijević‐Branković, Mirjana Rajilić‐Stojanović

et al.

Frontiers in Nutrition, Journal Year: 2021, Volume and Issue: 8

Published: July 30, 2021

Medicinal plants and their extracts contain substantial quantities of polyphenols. As metabolically active plant metabolites, polyphenols are food components with a wide range biological activities. Given poor absorbability in the digestive tract activity toward human host is typically mediated through interaction intestinal microbes. result, comprise novel group prebiotics. In this study, we tested effect five polyphenol-rich from four medicinal herbs on growth probiotic pathogenic The studied were Gentiana asclepiadea L. (willow gentian), Hypericum perforatum (St. John's wort), Satureja montana (winter savory), Achillea millefolium (yarrow). All these traditionally used for treatment problems. Extracts prepared using safe solvent combinations. We impact addition three lactobacilli yeast Saccharomyces boulardii . to liquid media (concentration 0.25–10 mg/mL) probiotics, was vitro antimicrobial against several opportunistic bacteria yeast. St. wort, winter savory, willow gentian showed stimulative growth, while highest growth-stimulating achieved when microwave-assisted yarrow extract concentration 0.5 mg/mL. Under conditions S. increased 130-fold. addition, stimulated Lactiplantibacillus plantarum 299v. two Lacticasibacillus rhamnosus strains not by any extracts. Our results show that can influence microorganisms typical members microbiota. For first time demonstrate be herbs, which accompanied suppression Candida yeasts suggests potential benefit diseases associated fungal dysbiosis.

Language: Английский

Citations

77

Does four-week consecutive, dawn-to-sunset intermittent fasting during Ramadan affect cardiometabolic risk factors in healthy adults? A systematic review, meta-analysis, and meta-regression DOI
Haitham Jahrami, MoezAlIslam E. Faris,

Abdulrahman Janahi

et al.

Nutrition Metabolism and Cardiovascular Diseases, Journal Year: 2021, Volume and Issue: 31(8), P. 2273 - 2301

Published: May 25, 2021

Language: Английский

Citations

71