Suspect and Nontarget Screening Reveal the Underestimated Risks of Antibiotic Transformation Products in Wastewater Treatment Plant Effluents

Environmental Science & Technology, Journal Year: 2023, Volume and Issue: 57(45), P. 17439 - 17451

Published: Nov. 6, 2023

Antibiotics are anthropogenic contaminants with a global presence and of deep concern in aquatic environments, while less is known about the occurrence risks their transformation products (TPs). Herein, we developed comprehensive suspect nontarget screening workflow based on high-resolution mass spectrometry to identify unknown antibiotic TPs wastewater treatment plant effluents. We identified 211 compounds (35 parent antibiotics 176 TPs) at confidence levels ≥3 107 originated from macrolides. were quantified by 17 standards semiquantified predicted response factors accounted for 55.6-95.1% (76.7% average) total concentrations parents TPs. 22.2%, 63.1%, 18.8% estimated be more persistent, mobile, toxic than antibiotics, respectively. Further ecological risk assessment toxicity organisms revealed that cumulative generally higher those parents. Despite newly formed N-oxide TPs, tertiary process (mainly ozonation) could decrease averaged 20.3% 36.2% antibiotic-related compounds. This study highlights necessity include environmental scrutiny different environments.

Language: Английский

---

Discovering Novel Organophosphorus Compounds in Wastewater Treatment Plant Effluents through Suspect Screening and Nontarget Analysis

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: 58(14), P. 6402 - 6414

Published: March 28, 2024

Limited knowledge on the structure of emerging organophosphorus compounds (OPCs) hampers our comprehensive understanding their environmental occurrence and potential risks. Through suspect nontarget screening, combining data-dependent acquisition, data-independent parallel reaction monitoring modes, we identified 60 OPCs (17 traditional 43 compounds) in effluents 14 wastewater treatment plants (WWTPs) Beijing Qinghai, China. These comprise 26 organophosphate triesters, 17 diesters, 6 organophosphonates, 7 organothiophosphate esters, 4 other OPCs. Notably, were newly WWTP effluents, 16 discovered matrices. Specifically, cyclic phosphonate, (5-ethyl-2-methyl-1,3,2-dioxaphosphorinan-5-yl)methyl dimethyl phosphonate P-oxide (PMMMPn), consistently appeared all with semiquantitative concentrations ranging from 44.4 to 282 ng/L. Its analogue, di-PMMMPn, presented 93% samples. Compositional differences between two cities mainly attributed Hazard ecological risk assessment underscored substantial contribution chlorinated esters overall risks effluents. This study provides most OPC profiles date, highlighting need for further research occurrence, fate, risks, particularly

Language: Английский

---

Greenhouse gas emission during swine manure aerobic composting: Insight from the dissolved organic matter associated microbial community succession

Bioresource Technology, Journal Year: 2023, Volume and Issue: 373, P. 128729 - 128729

Published: Feb. 11, 2023

Language: Английский

---

Delivering on sustainable development goals in wastewater reuse for agriculture: Initial prioritization of emerging pollutants in the Tula Valley, Mexico

Water Research, Journal Year: 2023, Volume and Issue: 238, P. 119903 - 119903

Published: March 24, 2023

Wastewater reuse for agricultural irrigation is a widespread beneficial practice, in line with the sustainable development goals. However, contaminants of emerging concern (CECs) present wastewater, such as pharmaceuticals, pose an environmental risk. The Tula Valley Mexico one world's largest areas reusing wastewater agriculture. no untargeted CEC monitoring has been undertaken there, limiting information available to prioritise local risk assessment. Furthermore, presence Global South remains understudied, compared North. There that current research efforts focus on CECs predominantly found North, leading strategies may not be appropriate where pollution profile different. To address these knowledge gaps, sampling campaign at five key sites was and samples analysed using multi-residue targeted liquid chromatography mass spectrometry methods. Using data, ten were least site: 4‑tert-octylphenol, acetaminophen, bezafibrate, diclofenac, erythromycin, levonorgestrel, simvastatin, sulfamethoxazole, trimethoprim tramadol well total estrogenicity (combination three steroid hormones). Six have previously quantified Valley. Over hundred pollutants never measured area identified through analysis supported by library spectrum match. Examples include diclofenac carbamazepine metabolites area-specific herbicide fomesafen. This contributes characterising South, providing site-specific data

Language: Английский

---

Nontarget Identification of Novel Organophosphorus Flame Retardants and Plasticizers in Rainfall Runoffs and Agricultural Soils around a Plastic Recycling Industrial Park

Environmental Science & Technology, Journal Year: 2023, Volume and Issue: 57(34), P. 12794 - 12805

Published: Aug. 14, 2023

Plastic recycling and reprocessing activities may release organophosphate ester (OPE) flame retardants plasticizers into the surrounding environment. However, relevant contamination profiles impacts remain not well studied. This study investigated occurrence of 28 OPEs their metabolites (mOPEs) in rainfall runoffs agricultural soils around one largest plastic industrial parks North China identified novel organophosphorus compounds (NOPs) using high-resolution mass spectrometry-based nontarget analysis. Twenty twenty-seven were detected runoff water soil samples, with total concentrations 86.0–2491 ng/L 2.53–199 ng/g dw, respectively. Thirteen NOPs identified, which eight reported environment for first time, including a chlorine-containing OPE, an heterocycle, phosphite, three OPE metabolites, two oligomers. Triphenylphosphine oxide diphenylphosphinic acid occurred ubiquitously soils, up to 390 40.2 The downwind areas park showed elevated levels NOPs. contribution hydroxylated mOPEs was higher than runoffs. These findings suggest that are significant sources biotransformation further increase ecological human exposure risk.

Language: Английский

---

Nontarget Identification of Novel Organophosphorus Flame Retardants and Plasticizers in Indoor Air and Dust from Multiple Microenvironments in China

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: 58(18), P. 7986 - 7997

Published: April 24, 2024

The indoor environment is a typical source for organophosphorus flame retardants and plasticizers (OPFRs), yet the characteristics of OPFRs in different microenvironments remain less clear. This study collected 109 air samples 34 paired dust from 4 within university Tianjin, China, including dormitory, office, library, information center. 29 target were analyzed, novel compounds (NOPs) identified by fragment-based nontarget analysis. Target exhibited highest concentrations 46.2–234 ng/m3 20.4–76.0 μg/g, respectively, center, where chlorinated dominant. Triphenyl phosphate (TPHP) was primary OPFR office air, while tris(2-chloroethyl) dominated dust. TPHP predominant library. Triethyl (TEP) ubiquitous tris(2-butoxyethyl) particularly high 9 25 NOPs first time, mainly center such as bis(chloropropyl) 2,3-dichloropropyl phosphate. Diphenyl phosphinic acid, two hydroxylated methylated metabolites tris(2,4-ditert-butylphenyl) phosphite (AO168), dimer newly reported environment. widely associated with OPFRs, their human exposure risk environmental behaviors warrant further study.

Language: Английский

---

Exploring organic and inorganic contaminant histories in sediment cores across the anthropocene: Accounting for site/area dependent factors

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 470, P. 134168 - 134168

Published: April 7, 2024

Sedimentary records help chronologically identify anthropogenic contamination in environmental systems. This study analysed dated sediment cores from L'Albufera Lake (Valencia, Spain), to assess the occurrence of heavy metals (HMs), polycyclic aromatic hydrocarbons (PAHs), perfluoroalkyl substances (PFASs), organophosphorus flame retardants (OPFRs), pesticides and pharmaceuticals personal care products (PPCPs). The results evidence continuing vertical presence all types contaminants this location. age was difficult establish. However, shells together with an historical estimation knowledge sedimentary rates could help. HMs contents are higher upper layer reflecting most recent increase industrial agricultural practices area since middle 20th century. Higher availability index these layers is associated point diffuse sources area. PAHs OPFRs were homogeneous distributed through sediments few exceptions such as phenanthrene North fluoranthene South. Perfluorooctanoic acid (PFOA) perfluorooctanesulfonate (PFOS) detected throughout core while short-chain PFASs (except Perfluoropentanoic (PFPeA)) only top layer. Pesticides PPCPs showed appreciable down-core mobility. concentration profiles organic did not exhibit a clear trend depth, then, it develop direct relationship between contaminant concentrations, elucidate based on core. Consequently, linking occurrences directly use somewhat speculative at least conditions Lake.

Language: Английский

---

Identification of Novel Organophosphate Esters in Hydroponic Lettuces (Lactuca sativa L.): Biotransformation and Acropetal Translocation

Environmental Science & Technology, Journal Year: 2022, Volume and Issue: 56(15), P. 10699 - 10709

Published: July 18, 2022

The absorption, translocation, and biotransformation behaviors of organophosphate esters (OPEs) diesters (OPdEs) in a hydroponic system were investigated. lateral root was found as the main accumulation place OPEs OPdEs lettuce. nontarget analysis using high-resolution mass spectrometry revealed five hydroxylated metabolites conjugating OPE exposure group, among which methylation, acetylation, palmitoyl reported for first time. Particularly, methylation on phosphate can be significant process plant metabolism, methyl diphenyl (MDPP) accounted majority metabolites. translocation factor values most identified are negatively associated with their predicted logarithmic octanol–water partitioning coefficient (log Kow) (0.75–2.45), indicating that hydrophilicity is dominant In contrast, conjugation may lead to an enhanced acropetal those log Kow < 0 have limited potential. Additionally, produced from lettuce showed higher potential than exposed directly. These results further emphasize necessity consider utmost important plants.

Language: Английский

---

Characterizing the spatiotemporal distribution of dissolved organic matter (DOM) in the Yongding River Basin: Insights from flow regulation

Journal of Environmental Management, Journal Year: 2022, Volume and Issue: 325, P. 116476 - 116476

Published: Oct. 27, 2022

Language: Английский

---

Combining Passive Sampling with Suspect and Nontarget Screening to Characterize Organic Micropollutants in Streams Draining Mixed-Use Watersheds

Environmental Science & Technology, Journal Year: 2022, Volume and Issue: 56(23), P. 16726 - 16736

Published: Nov. 4, 2022

Organic micropollutants (OMPs) represent an anthropogenic stressor on stream ecosystems. In this work, we combined passive sampling with suspect and nontarget screening enabled by liquid chromatography–high-resolution mass spectrometry to characterize complex mixtures of OMPs in streams draining mixed-use watersheds. Suspect identified 122 unique for target quantification polar organic chemical integrative samplers (POCIS) grab samples collected from 20 sites upstate New York over two seasons. Hierarchical clustering established the co-occurrence profiles connection watershed attributes indicative influences. Nontarget leveraging time-integrative nature POCIS cross-site variability prioritized confirmed 11 additional compounds that were ubiquitously present monitored streams. Field rates 37 simultaneously occurred spanned range 0.02 0.22 L/d a median value 0.07 L/d. Comparative analyses daily average loads, cumulative exposure–activity ratios, multi-substance potentially affected fractions supported feasibility complementing OMP load estimation screening-level risk assessments. Overall, work demonstrated multi-watershed approach can be adapted assess contamination across landscapes.

Language: Английский

---