Environmental Science & Technology,
Journal Year:
2023,
Volume and Issue:
58(1), P. 510 - 521
Published: Dec. 15, 2023
Fluorinated
liquid
crystal
monomers
(FLCMs)
have
been
suggested
as
emerging
contaminants,
raising
global
concern
due
to
their
frequent
occurrence,
potential
toxic
effects,
and
endurance
capacity
in
the
environment.
However,
environmental
fate
of
FLCMs
remains
unknown.
To
fill
this
knowledge
gap,
we
investigated
aerobic
microbial
transformation
mechanisms
an
important
FLCM,
4-[difluoro(3,4,5-trifluorophenoxy)methyl]-3,
5-difluoro-4′-propylbiphenyl
(DTMDPB),
using
enrichment
culture
termed
BG1.
Our
findings
revealed
that
67.5
±
2.1%
initially
added
DTMDPB
was
transformed
10
days
under
optimal
conditions.
A
total
14
products
obtained
a
series
reactions
(e.g.,
reductive
defluorination,
ether
bond
cleavage,
demethylation,
oxidative
hydroxylation
aromatic
ring
opening,
sulfonation,
glucuronidation,
O-methylation,
thiolation)
were
identified.
Consortium
BG1
harbored
essential
genes
could
transform
DTMDPB,
such
dehalogenation-related
[e.g.,
glutathione
S-transferase
gene
(GST),
2-haloacid
dehalogenase
(2-HAD),
nrdB,
nuoC,
nuoD];
hydroxylating-related
hcaC,
ubiH,
COQ7;
opening-related
ligB
catE;
methyltransferase
ubiE
ubiG.
Two
DTMDPB-degrading
strains
isolated,
which
are
affiliated
with
genus
Sphingopyxis
Agromyces.
This
study
provides
novel
insight
into
FLCMs.
The
implications
for
development
bioremediation
strategies
aimed
at
addressing
sites
contaminated
Eco-Environment & Health,
Journal Year:
2023,
Volume and Issue:
2(3), P. 131 - 141
Published: July 18, 2023
Liquid
crystal
monomers
(LCMs)
are
a
family
of
synthetic
organic
chemicals
applied
in
the
liquid
displays
(LCDs)
various
electric
and
electronic
products
(e-products).
Due
to
their
unique
properties
(i.e.,
persistence,
bioaccumulative
potential,
toxicity)
widespread
environmental
distributions,
LCMs
have
attracted
increasing
attention
across
world.
Recent
studies
focused
on
source,
distribution,
fate,
toxicity
LCMs;
however,
comprehensive
review
is
scarce.
Herein,
we
highlighted
persistence
bioaccumulation
potential
by
reviewing
physical-chemical
properties.
The
naming
rules
were
suggested
standardize
abbreviations
regarding
LCMs.
sources
occurrences
different
compartments,
including
dust,
sediment,
soil,
leachate,
air
particulate,
human
serum,
biota
samples,
reviewed.
It
concluded
that
environment
mainly
originate
from
usage
disassembly
e-products
with
LCDs.
Moreover,
recycling
removal
technologies
waste
LCD
panels
suggests
combination
natural
attenuation
physic-chemical
remediation
should
be
developed
for
remediations
future.
By
health
risks
LCMs,
it
found
large
gap
exists
risk
organisms.
fate
investigation
further
investigations
effects
exposure
residents,
especially
occupational
workers,
considered
Journal of Agricultural and Food Chemistry,
Journal Year:
2024,
Volume and Issue:
72(33), P. 18401 - 18411
Published: Aug. 2, 2024
The
uptake,
translocation,
and
accumulation
of
mefentrifluconazole
(MFZ),
an
innovative
chiral
triazole
fungicide,
in
plants
at
the
enantiomeric
level
are
still
unclear.
Herein,
we
investigated
patterns
mechanisms
bioaccumulation,
translocation
through
several
experiments.
Rac-MFZ
shows
strongest
uptake
bioaccumulation
capacity
wheat
compared
with
its
enantiomers,
while
S-(+)-MFZ
has
highest
potential.
Molecular
docking
provided
evidence
stronger
ability
than
R-(-)-MFZ.
Split-root
experiments
showed
that
MFZ
enantiomers
could
undergo
long-distance
transport
within
wheat.
Active
or
facilitated
simple
diffusion
may
be
involved
MFZ.
limited
acropetal
capability
attributed
to
dominant
pathway
apoplastic.
concentrations
different
subcellular
fractions
varied
greatly.
In
summary,
this
study
provides
novel
insights
for
further
understanding
behaviors
plants.
Nature Communications,
Journal Year:
2025,
Volume and Issue:
16(1)
Published: Jan. 31, 2025
Embryonic
and
fetal
development
can
be
affected
during
gestation
by
exposure
to
xenobiotics
that
cross
the
placenta.
Liquid
crystal
monomers
(LCMs)
are
emerging
contaminants
commonly
found
in
indoor
environments;
however,
whether
they
placenta
affect
placental
remains
unexplored.
Here,
we
develop
an
evaluation
system
integrates
human
biomonitoring,
uterine
perfusion
pregnant
rats,
cells.
We
find
fourteen
out
of
fifty-six
LCMs
detected
maternal
cord
serum
samples
from
ninety-three
healthy
women,
at
median
levels
13.9
18.1
ng/mL,
respectively.
Subsequent
explorations
utero
rats
indicate
aromatic
amino
acid
transporter
1
(SLC16A10)
mediates
transplacental
transportation
LCMs.
Placental
cells
exposed
exhibit
delayed
reduced
progesterone
release.
These
findings
show
SLC16A10-mediated
inhibits
release,
highlighting
importance
gestational
contaminants.
contaminants;
authors
SLC16A10-
mediated
