Indus journal of bioscience research.,
Journal Year:
2025,
Volume and Issue:
3(3), P. 19 - 35
Published: March 14, 2025
Microplastics,
which
are
small
plastic
particles
less
than
5
millimeters
in
size,
originate
from
the
degradation
of
larger
items
or
intentionally
manufactured
for
various
uses.
These
have
become
ubiquitous
marine
and
freshwater
environments,
posing
significant
risks
to
aquatic
life
due
their
ability
absorb
concentrate
hazardous
pollutants.
The
exposure
Microplastics
(MPs),
leads
DNA
damage
fish
that
alters
hematological
parameters
causes
oxidative
stress,
thereby
impacting
overall
health
organisms.
MPs
also
induce
an
imbalance
reactive
oxygen
species
(ROS)
production
antioxidant
capacity,
causing
damage.
In
addition,
impact
immune
responses
physical
chemical
toxicity
cause
neurotoxicity,
altering
AchE
activity.
This
review
highlights
toxic
effects
through
indicators
were
examined
including
bioaccumulation,
parameters,
responses,
neurotoxicity
relation
MP
exposure,
facilitating
identification
biomarkers
following
fish.
study
digestive
tract
contains
more
microplastics
(MPs)
gills,
with
fragments,
fibers,
films,
pellets
being
predominant
types.
FTIR
analysis
identified
polyethylene,
polystyrene,
polyvinylchloride,
polyamide,
polycarbonate
both
gills
system.
pollution
triggered
stress
gambusia
East
Java
Brantas
River.
While
PVC-MPs
did
not
significantly
affect
gill
histopathology
ion
regulation,
combined
Cu
individual
findings
emphasize
need
further
research
on
heavy
metals
ecosystems.
Antioxidants,
Journal Year:
2024,
Volume and Issue:
13(5), P. 579 - 579
Published: May 8, 2024
Microplastics
(MPs)
are
plastic
particles
between
0.1
and
5000
µm
in
size
that
have
attracted
considerable
attention
from
the
scientific
community
general
public,
as
they
threaten
environment.
contribute
to
various
harmful
effects,
including
lipid
peroxidation,
DNA
damage,
activation
of
mitogen-activated
protein
kinase
pathways,
cell
membrane
breakages,
mitochondrial
dysfunction,
lysosomal
defects,
inflammation,
apoptosis.
They
affect
cells,
tissues,
organs,
overall
health,
potentially
contributing
conditions
like
cancer
cardiovascular
disease.
pose
a
significant
danger
due
their
widespread
occurrence
food.
In
recent
years,
information
has
emerged
indicating
MPs
can
cause
oxidative
stress
(OS),
known
factor
accelerating
aging
organisms.
This
comprehensive
evaluation
exposed
notable
variability
reported
connection
OS.
work
aims
provide
critical
review
whether
harmfulness
constitute
environmental
contaminants
may
result
OS
through
analysis
research
existing
literature,
well
an
assessment
characteristics
causing
Additionally,
article
covers
analytical
methodology
used
this
field.
The
conclusions
point
necessity
for
further
into
effects
on
Metabolites,
Journal Year:
2022,
Volume and Issue:
12(10), P. 897 - 897
Published: Sept. 23, 2022
Mitochondria
are
highly
dynamic
cellular
organelles
that
perform
crucial
functions
such
as
respiration,
energy
production,
metabolism,
and
cell
fate
decisions.
Mitochondrial
damage
dysfunction
critically
lead
to
the
pathogenesis
of
various
diseases
including
cancer,
diabetes,
neurodegenerative
cardiovascular
disorders.
in
response
environmental
contaminant
exposure
its
association
with
has
also
been
reported.
Recently,
persistent
pollutants,
micro-
nanoplastics,
have
become
growing
global
threats
potential
health
risks.
In
this
review,
we
discuss
impact
nanoplastics
on
mitochondria
review
current
knowledge
field.
