Polysaccharides with antioxidant activity: Extraction, beneficial roles, biological mechanisms, structure-function relationships, and future perspectives: A review

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 300, P. 140221 - 140221

Published: Jan. 22, 2025

Language: Английский

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Achyranthes bidentata polysaccharide ameliorates type 2 diabetes mellitus by gut microbiota-derived short-chain fatty acids-induced activation of the GLP-1/GLP-1R/cAMP/PKA/CREB/INS pathway

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 270, P. 132256 - 132256

Published: May 9, 2024

Language: Английский

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Critical review on the research of chemical structure, bioactivities, and mechanism of actions of Dendrobium officinale polysaccharide

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 263, P. 130315 - 130315

Published: Feb. 19, 2024

Language: Английский

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(−)-Epicatechin ameliorates type 2 diabetes mellitus by reshaping the gut microbiota and Gut–Liver axis in GK rats

Food Chemistry, Journal Year: 2024, Volume and Issue: 447, P. 138916 - 138916

Published: March 6, 2024

Language: Английский

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Influence of Bariatric Surgery on Gut Microbiota Composition and Its Implication on Brain and Peripheral Targets

Nutrients, Journal Year: 2024, Volume and Issue: 16(7), P. 1071 - 1071

Published: April 5, 2024

Obesity remains a significant global health challenge, with bariatric surgery remaining as one of the most effective treatments for severe obesity and its related comorbidities. This review highlights multifaceted impact beyond mere physical restriction or nutrient malabsorption, underscoring importance gut microbiome neurohormonal signals in mediating profound effects on weight loss behavior modification. The various procedures, such Roux-en-Y gastric bypass (RYGB) sleeve gastrectomy (SG), act through distinct mechanisms to alter microbiome, subsequently impacting metabolic health, energy balance, food reward behaviors. Emerging evidence has shown that induces changes composition notably altering Firmicutes/Bacteroidetes ratio enhancing populations beneficial bacteria Akkermansia. These microbiota shifts have far-reaching influencing dopamine-mediated pathways brain modulating secretion action key hormones including ghrelin, leptin, GLP-1, PYY, CCK. resultant dopamine signaling hormone levels contribute reduced hedonic eating, enhanced satiety, improved outcomes. Further, post-bariatric surgical satiation targets are part mediated by byproducts like short-chain fatty acids (SCFAs) bile acids, which play pivotal role metabolism expenditure reducing obesity-associated inflammation, well pathways, potentially contributing regulation body reduction eating Overall, better understanding these opens door developing non-surgical interventions replicate signaling, regulation, offering new avenues treatment.

Language: Английский

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Alleviative effects of Dendrobium officinale polysaccharide on the quality deterioration of frozen dough and corresponding bread

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 140705 - 140705

Published: Feb. 1, 2025

Language: Английский

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Polysaccharides in Medicinal and Food Homologous plants regulate intestinal flora to improve type 2 diabetes: systematic review

Phytomedicine, Journal Year: 2024, Volume and Issue: 134, P. 156027 - 156027

Published: Sept. 3, 2024

Language: Английский

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The sweet corn cob selenium polysaccharide alleviates type 2 diabetes via modulation of LPS/IκBα/NFκB and the intestinal microbiota

Food Bioscience, Journal Year: 2024, Volume and Issue: 58, P. 103742 - 103742

Published: Feb. 12, 2024

Language: Английский

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The different parts of Dendrobium officinale Kimura et Migo: traditional uses, phytochemistry, pharmacological activities, and product development status and potential

Phytochemistry Reviews, Journal Year: 2024, Volume and Issue: unknown

Published: May 31, 2024

Language: Английский

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Exopolysaccharide from Lacticaseibacillus paracasei alleviates gastritis in Helicobacter pylori-infected mice by regulating gastric microbiota

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: June 24, 2024

Introduction Many probiotics have the ability to produce extracellular polysaccharides (EPS). EPS derived from these has been confirmed regulate host intestinal microecological balance and alleviate symptoms of diseases caused by gastrointestinal imbalance. Results Lactic acid bacteria (LAB) strain with good exopolysaccharide (EPS) producing ability, namely, Lacticaseibacillus paracasei ZFM54 ( L. ZFM54) was screened. The fermentation conditions for production were optimized. EPS54 characterized chemical component monosaccharide composition determination, UV, FT-IR NMR spectra analysis. Cango red, SEM, AFM XRD analysis conducted characterize structure EPS54. effectively reduced colonization Helicobacter pylori AGS cells recovered cell morphology. could also gastritis in H. -infected mice down-regulating mRNA expression levels pro-inflammatory cytokines IL-6, IL-8, IL-1β TNF-α up-regulating inflammatory cytokine IL-10 gastric cells. found be able positively microbiota. Conclusion 54 can modulating

Language: Английский

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