Journal of Pure and Applied Microbiology,
Journal Year:
2024,
Volume and Issue:
18(2), P. 797 - 807
Published: May 27, 2024
Tremendous
increase
in
anthropogenic
activities
and
natural
disasters
have
created
long
term
negative
impacts
to
the
crop
productivity
as
well
on
our
ecosystem.
In
debate
regarding
ongoing
ecosystem
fluctuations,
there
is
a
need
explore
an
efficient,
cost-effective,
target-oriented
less
manpower-based
technologies
for
sustainable
development.
Microbial
engineering
provides
better
solution
growth
of
healthy
environment
higher
agricultural
over
existing
methods
resolved
challenges
worldwide
related
development
agriculture
greener
ecosystems.
recent
years,
researchers
are
working
different
advanced
microbial
strategies
such
gene
editing,
CRISPR/Cas9,
RNAi
enhance
potential
microorganisms
towards
plant
degradation
pollutants.
The
present
review
focused
applications
genetically
engineered
inoculants
Journal of Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: Nov. 15, 2024
Abstract
Nanotechnology
holds
immense
promise
in
revolutionising
healthcare,
offering
unprecedented
opportunities
diagnostics,
drug
delivery,
cancer
therapy,
and
combating
infectious
diseases.
This
review
explores
the
multifaceted
landscape
of
nanotechnology
healthcare
while
addressing
critical
aspects
safety
environmental
risks
associated
with
its
widespread
application.
Beginning
an
introduction
to
integration
we
first
delved
into
categorisation
various
materials
employed,
setting
stage
for
a
comprehensive
understanding
potential.
We
then
proceeded
elucidate
diverse
applications
nanotechnology,
spanning
medical
tissue
engineering,
targeted
gene
development
antimicrobial
agents.
The
discussion
extended
current
situation
surrounding
clinical
translation
commercialisation
these
cutting-edge
technologies,
focusing
on
nanotechnology-based
products
that
have
been
approved
globally
date.
also
discussed
considerations
nanomaterials,
both
terms
human
health
impact.
presented
vivo
nanomaterial
exposure,
relation
transport
mechanisms,
oxidative
stress,
physical
interactions.
Moreover,
highlighted
risks,
acknowledging
potential
implications
ecosystems
biodiversity.
Lastly,
strived
offer
insights
regulatory
governing
across
different
regions
globally.
By
synthesising
perspectives,
underscore
imperative
balancing
innovation
stewardship,
charting
path
forward
responsible
healthcare.
Graphical
abstract
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: June 26, 2024
The
development
of
nanomaterials
has
been
speedily
established
in
recent
years,
yet
nanoparticles
synthesized
by
traditional
methods
suffer
unacceptable
toxicity
and
the
sustainability
procedure
for
synthesizing
such
is
inadequate.
Consequently,
green
biosynthesis,
which
employs
biopolymers,
gaining
attraction
as
an
environmentally
sound
alternative
to
less
sustainable
approaches.
Chitosan-encapsulated
exhibit
exceptional
antibacterial
properties,
offering
a
wide
range
uses.
Chitosan,
obtained
from
shrimp
shells,
aided
friendly
synthesis
high-purity
zinc
oxide
(ZnO
NPs)
with
desirable
features
extraction
yield
(41%),
deacetylation
(88%),
crystallinity
index
(74.54%).
particle
size
ZnO
NPs
was
12
nm,
while
that
chitosan-ZnO
21
bandgap
energies
these
were
3.98
3.48,
respectively.
strong
action
demonstrated
NPs,
chitosan-ZnO/PVP,
particularly
against
Gram-positive
bacteria,
making
them
appropriate
therapeutic
use.
photocatalytic
degradation
abilities
also
assessed
all
nanoparticles.
At
concentration
6
×
10
Advanced Science,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 23, 2024
The
continuous
imbalance
of
the
diabetic
wound
microenvironment
is
an
important
cause
chronic
nonhealing,
which
manifests
as
a
vicious
cycle
between
excessive
accumulation
reactive
oxygen
species
(ROS)
and
abnormal
healing.
Regulating
by
suppressing
inflammation,
oxidative
stress,
bacterial
infection
key
challenge
in
treating
wounds.
In
this
study,
ROS-responsive
hydrogels
are
developed
composed
silk
fibroin
methacrylated
(SFMA),
modified
collagen
type
III
(rCol
Deleted Journal,
Journal Year:
2024,
Volume and Issue:
1(1)
Published: Oct. 29, 2024
The
integration
of
immunotoxicity
data
into
chemical
risk
assessment
paradigms
is
essential
for
comprehensively
evaluating
the
potential
health
hazards
posed
by
exposures.
This
review
provides
a
comprehensive
overview
methodologies,
challenges,
and
future
directions
integrating
frameworks.
It
discusses
fundamental
principles
immunotoxicology
its
relevance
to
assessment,
highlighting
critical
roles
immune
system
in
defense
against
harmful
agents.
Next,
we
explore
traditional
frameworks,
including
exposure
hazard
identification,
dose–response
characterization,
need
incorporating
endpoints
enhance
characterization
estimation.
Subsequently,
delve
modelling
immunotoxicity,
elucidating
principles,
methods,
case
studies
illustrating
relationships
extrapolation
from
animal
humans.
Furthermore,
discuss
focusing
on
identification
immunotoxic
hazards,
evaluation
endpoints,
utilization
immunological
biomarkers
assessment.
We
then
examine
cumulative
strategies,
presenting
conceptual
framework
assessing
risks
multiple
exposures
methods
different
chemicals.
Lastly,
emerging
trends
high-throughput
screening
assays,
omics
technologies,
computational
modelling,
alternative
testing
along
with
regulatory
implications
research
needs.
valuable
insights
researchers,
regulators,
stakeholders
involved
public
protection,
facilitating
development
evidence-based
strategies
safeguarding
human
associated
Discover Nano,
Journal Year:
2024,
Volume and Issue:
19(1)
Published: April 9, 2024
Modern
imaging
strategies
are
paramount
to
studying
living
systems
such
as
cells,
bacteria,
and
fungi
their
response
pathogens,
toxicants,
nanomaterials
(NMs)
modulated
by
exposure
environmental
factors.
The
need
understand
the
processes
mechanisms
of
damage,
healing,
cell
survivability
continues
motivate
development
alternative
strategies.
Of
particular
interest
is
use
label-free
techniques
(microscopy
procedures
that
do
not
require
sample
staining)
minimize
interference
biological
foreign
marking
substances
reduce
intense
light
potential
photo-toxicity
effects.
This
review
focuses
on
synergic
capabilities
atomic
force
microscopy
(AFM)
a
well-developed
robust
strategy
with
demonstrated
applications
unravel
intimate
details
in
biomedical
applications,
label-free,
fast,
enduring
Holotomographic
Microscopy
(HTM)
strategy.
HTM
technique
combines
holography
tomography
using
low
intensity
continuous
illumination
laser
investigate
(quantitatively
non-invasively)
microorganisms,
thin
tissue
generating
three-dimensional
(3D)
images
monitoring
real-time
inner
morphological
changes.
We
first
operating
principles
form
basis
for
complementary
provided
these
regarding
surface
internal
information
AFM,
which
essential
complimentary
several
areas
interaction
NMs
organisms.
First,
AFM
can
provide
superb
resolution
morphology
biomechanical
characterization.
Second,
quantitative
phase
enable
modeling
quantification
volume,
area,
protein
content,
mass
density
main
components
cells
including
microbiological
systems.
These
result
from
directly
quantifying
refractive
index
changes
without
requiring
fluorescent
markers
or
chemicals.
As
such,
ideal
long-term
organisms
conditions
close
natural
settings.
present
case-based
principal
uses
both
contributions
nanomedicine
nanotoxicology
(study
harmful
effects
organisms),
emphasizing
cancer
infectious
disease
control.
impact
sequential
provides
clear
drive
adopting
interdependent
fundamental
tools.
