Macromolecular Rapid Communications,
Journal Year:
2024,
Volume and Issue:
45(17)
Published: May 28, 2024
Stimuli-responsive
low
molecular
weight
hydrogel
interventions
for
Biomedical
challenges
are
a
rapidly
evolving
paradigm
in
the
bottom-up
approach
recently.
Peptide-based
self-assembled
nano
biomaterials
present
safer
alternatives
to
their
non-degradable
counterparts
as
demanded
today's
most
urged
clinical
needs.Although
plethora
of
work
has
already
been
accomplished,
programming
hydrogelators
with
appropriate
functionalities
requires
better
understanding
impact
macromolecular
structure
peptides
and
subsequently,
nanostructures
remain
unidentified.
Henceforth
this
review
focuses
on
two
aspects:
Firstly,
underlying
guidelines
building
biomimetic
strategies
tailor
scaffolds
leading
hydrogelation
along
role
non-covalent
interactions
that
key
components
various
self-assembly
processes.
In
second
section,
it
is
aimed
bring
together
recent
achievements
designer
assembly
concerning
self-aggregation
behaviour
applications
mainly
biomedical
arena
like
drug
delivery
carrier
design,
antimicrobial,
anti-inflammatory
well
wound
healing
materials.
Furthermore,
anticipated
article
will
provide
conceptual
demonstration
different
approaches
taken
towards
construction
these
task-specific
hydrogels.
Finally,
collective
effort
among
material
scientists
required
pave
path
entrance
intelligent
materials
into
medicine
from
bench
bedside.
ChemPhysMater,
Journal Year:
2022,
Volume and Issue:
1(4), P. 294 - 309
Published: April 29, 2022
Zwitterionic
polymers
have
attracted
research
attention
in
recent
years
owing
to
their
unique
molecular
structures.
In
the
same
repeat
unit,
positive
and
negative
charges
are
simultaneously
located
on
a
pair
of
cationic
anionic
groups;
therefore,
zwitterionic
large
dipole
moment
numerous
charged
groups.
Although
chain
polymer
can
be
maintained
an
electrically
neutral
state
overall,
coexistence
oppositely
groups
confers
extremely
high
polarity
excellent
hydrophilicity
polymer.
At
time,
electricality
further
regulated
by
environmental
pH
salt
ions,
which
greatly
broadens
scope
applications
different
fields.
This
review
introduces
various
structures
analyzes
reasons
why
exhibit
responsiveness,
anti-polyelectrolyte
effects,
superior
electrical
conductivity.
The
application
fields
also
summarized
generalizing
status
polymers,
including
antifouling
coatings,
drug
delivery,
wastewater
treatment,
sensors,
etc.
Small,
Journal Year:
2023,
Volume and Issue:
20(5)
Published: Sept. 26, 2023
Abstract
Microbial
infections
based
on
drug‐resistant
pathogenic
organisms
following
surgery
or
trauma
and
uncontrolled
bleeding
are
the
main
causes
of
increased
mortality
from
worldwide.
The
prevalence
pathogens
has
led
to
a
significant
increase
in
medical
costs
poses
great
threat
normal
life
people.
This
is
an
important
issue
field
biomedicine,
emergence
new
antimicrobial
materials
hydrogels
holds
promise
for
solving
this
problem.
Hydrogel
material
with
good
biocompatibility,
water
absorption,
oxygen
permeability,
adhesion,
degradation,
self‐healing,
corrosion
resistance,
controlled
release
drugs
as
well
structural
diversity.
Bacteria‐disturbing
have
applications
direction
surgical
treatment,
wound
dressing,
device
coating,
tissue
engineering.
paper
reviews
classification
hydrogels,
current
status
research,
potential
one
application
analyzes
research
biomedical
five
aspects:
metal‐loaded
drug‐loaded
carbon‐material‐loaded
fixed
activity
biological
provides
outlook
high
activity,
biodegradability,
injectability,
clinical
applicability
future
development
prospects
field.
Materials Horizons,
Journal Year:
2023,
Volume and Issue:
10(10), P. 4033 - 4058
Published: Jan. 1, 2023
In
this
paper,
the
structure
types,
optimization
mechanism
of
mechanical
properties
and
common
application
scenarios
bionic
ordered
hydrogels
are
reviewed.
Materials,
Journal Year:
2022,
Volume and Issue:
15(17), P. 5871 - 5871
Published: Aug. 25, 2022
Peptide-based
hydrogels
have
attracted
increasing
attention
for
biological
applications
and
diagnostic
research
due
to
their
impressive
features
including
biocompatibility
biodegradability,
injectability,
mechanical
stability,
high
water
absorption
capacity,
tissue-like
elasticity.
The
aim
of
this
review
will
be
present
an
updated
report
on
the
advancement
peptide-based
activity
in
recent
years
field
anticancer
drug
delivery,
antimicrobial
wound
healing
materials,
3D
bioprinting
tissue
engineering,
vaccines.
Additionally,
biosensing
key
group
discussed
mainly
focusing
cancer
detection.
