Study on the chiroptical properties of carbon dots based on citric acid and formamide with the addition of various chiral molecules DOI
Evgeniia A. Stepanidenko, Anna A. Vedernikova, Alexander M. Mitroshin

et al.

Journal of Optical Technology, Journal Year: 2024, Volume and Issue: 91(6), P. 421 - 421

Published: June 1, 2024

Subject of study. The study focuses on luminescent carbon nanoparticles, specifically dots, based citric acid, formamide, and various chiral molecules. Aim aim is to assess the influence molecules used in synthesis dots optical transitions long-wavelength spectral region investigate mechanism underlying circular dichroism signal these nanoparticles. Method. Carbon dot samples were synthesized using two methods: (i) a one-step solvothermal from (ii) two-step method involving achiral acid followed by surface treatment with L-cysteine. Absorption luminescence spectroscopy methods employed chemical structure properties dots. chiroptical obtained analyzed spectroscopy. Main results. addition mixture precursors during enabled fabrication different compositions, including variations groups types emission centers 350–700 nm. use L-phenylglycine L-tryptophan was shown lead formation nanoparticles both short- regions spectrum. L-glutathione resulted short-wavelength emission, while L-cysteine did not alter characteristics formamide. remained unchanged compared those spectra all showed at ∼250nm, which attributed derivatives attached irrespective preparation method. Practical significance. Chiral hold promise biomedicine as sensors, biomarkers, other applications due their biocompatibility non-toxicity. results this work will serve foundation for further investigation luminescence.

Language: Английский

D‐cysteine‐Derived Carbon Dots for Selective Discrimination, Imaging, and Synergistic Elimination of Gram‐Positive Bacteria and Fungi DOI
Wenzhu Song,

Xuexiao Wang,

Shuli Nong

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: 34(38)

Published: April 30, 2024

Abstract Microbial infections pose a significant threat to public health, exacerbated by the escalating issue of antibiotic resistance resulting from their overuse. Chiral carbon dots (CDs) not only inherit antibacterial properties CDs but also demonstrate highly selective chiral bactericidal activity. This study focuses on development synthesized D‐ and L‐cysteine, selectively identify synergistically eradicate Gram‐positive bacteria fungi. exhibit high efficacy in staining fungi while demonstrating minimal no fluorescence with Gram‐negative bacteria, attributable variances membrane structures these pathogens. D‐CDs stronger signals greater against compared L‐CDs. Under dual light irradiation, bolster activity through triple‐modal mechanism, involving disruption absence light, singlet oxygen generation during photodynamic therapy, elevated temperature photothermal treatment. Animal studies additionally showcase that notably enhanced healing wounds infected S. aureus under laser exposure. investigation underscores chiral‐specific imaging potentials D‐CDs, paving way for advancement nanomaterials bacterial diagnostics therapy.

Language: Английский

Citations

18
A review of carbon dots in synthesis, property and application DOI
Qian Wang,

Xinyi He,

Yuanda Lv

et al.

Materials Today Communications, Journal Year: 2025, Volume and Issue: unknown, P. 111824 - 111824

Published: Feb. 1, 2025

Language: Английский

Citations

2
Large Scale Synthesis of Carbon Dots and Their Applications: A Review DOI Creative Commons
Zhujun Huang, Lili Ren

Molecules, Journal Year: 2025, Volume and Issue: 30(4), P. 774 - 774

Published: Feb. 7, 2025

Carbon dots (CDs), a versatile class of fluorescent carbon-based nanomaterials, have attracted widespread attention due to their exceptional optical properties, biocompatibility, and cost-effectiveness. Their applications span biomedicine, optoelectronics, smart food packaging, yet large-scale synthesis remains significant challenge. This review categorizes methods into liquid-phase (hydrothermal/solvothermal, microwave-assisted, magnetic hyperthermia, aldol condensation polymerization), gas-phase (plasma synthesis), solid-phase (pyrolysis, oxidation/carbonization, ball milling), emerging techniques (microfluidic, ultrasonic, molten-salt). Notably, microwave-assisted solid-state show promise for industrial production scalability efficiency. Despite these advances, challenges persist in optimizing reproducibility, reducing energy consumption, developing purification quality control strategies. Addressing issues will be critical transitioning CDs from laboratory research real-world applications.

Language: Английский

Citations

2
Carbon Dots in the Pathological Microenvironment: ROS Producers or Scavengers? DOI
Chen Dong, Yanan Wang, Tianxiang Chen

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(29)

Published: July 22, 2024

Reactive oxygen species (ROS), as metabolic byproducts, play pivotal role in physiological and pathological processes. Recently, studies on the regulation of ROS levels for disease treatments have attracted extensive attention, mainly involving ROS-induced toxicity therapy mediated by producers antioxidant scavengers. Nanotechnology advancements led to development numerous nanomaterials with ROS-modulating capabilities, among which carbon dots (CDs) standing out noteworthy nanomedicines own their distinctive physicochemical properties, high stability, excellent biocompatibility. Despite progress treating ROS-related diseases based CDs, critical issues such rational design principles remain underexplored. The primary cause these may stem from intricate amalgamation core structure, defects, surface states, inherent poses challenges establishing a consistent generalization. This review succinctly summarizes recently ROS-modulated approaches using CDs treatment. Specifically, it investigates established therapeutic strategies CDs-regulated ROS, emphasizing interplay between intrinsic structure generation or scavenging ability. conclusion raises several unresolved key scientific prominent technological bottlenecks, explores future perspectives comprehensive CDs-based therapy.

Language: Английский

Citations

6
Gram-scale synthesis of aggregation-caused quenching-resistant red-emissive carbon dots for potential applications DOI
Ashok Kumar, Kanchan Negi, Sumanta Kumar Sahu

et al.

New Journal of Chemistry, Journal Year: 2024, Volume and Issue: 48(16), P. 7265 - 7276

Published: Jan. 1, 2024

This work describes the gram-scale synthesis of N/S-doped carbon dots for red emissive properties. The developed can be used in WLEDs, fingerprinting, bioimaging, fluorescent ink, and room-temperature phosphorescence.

Language: Английский

Citations

5
Binding effect of tyrosine-based chiral carbon dots on human serum albumin and lysozyme DOI
Zahra Hallaji, Zeinab Bagheri, Zeinab Tavassoli

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1316, P. 139041 - 139041

Published: June 15, 2024

Language: Английский

Citations

5
Chiral carbon dot as a fluorescent stain with enantiomer-dependent cell imaging DOI Creative Commons
Zahra Hallaji,

Seyed-Omid Kalji,

Zeinab Bagheri

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 16, 2025

Chiral carbon dots (CDs) are gaining significant interest because of their potential uses in the biological fields. The effects these nanoparticles highly influenced by chiral structure. influence CD's chirality on cell imaging with red emission, particularly both fixed and live states, has not been studied yet. Here, emissive CDs (LCD DCD) were prepared through a simple one-step method tyrosine (L D) phenylenediamine (ortho). LCD DCD share very identical properties, including optical absorption, fluorescence functional groups, size, zeta potential, only difference being chirality. Red emission minimizes tissue auto-fluorescence interference enhances penetration depth, making ideal for imaging. As staining agents, LCDs effectively enter cells predominantly localize cytoplasm nucleolus but brightness is lower than able to identify nucleoli. In addition, DCDs biocompatible, exhibit much toxicity. show toxicity from 20 µg.mL-1, while this effect 150 µg.mL-1. different performance between isomers due spatial structure, which affects interaction biomolecules cellular uptake. These factors affect ability penetrate cells, within specific regions, cytotoxicity, generate signals. expected lead development smart materials enhanced efficiency various applications.

Language: Английский

Citations

0
Efficient Mechanochemical Conversion of Elemental Sulfur to Circularly Polarized Luminescent Sulfur Quantum Dots DOI
Hammad Hasan,

Kulbir kulbir,

Pankaj Kumar

et al.

The Journal of Physical Chemistry C, Journal Year: 2024, Volume and Issue: 128(19), P. 8114 - 8122

Published: May 1, 2024

The chiroptical property of sulfur quantum dots (Sdots) is unexplored. Herein, we develop an efficient mechanochemical synthesis strategy for chiroptically active l-Sdots, revealing their ground-state and excited-state properties. detailed structural study confirmed a polymeric core with orthorhombic α-S8 phase stabilized capped by cystine functionalities. l-Sdots exhibit strong photoluminescence (PL), originating from defect states the vacancy, consequently facilitate electron migration toward surface groups. arises outer shell core, enriched cystine-related Conversely, circularly polarized luminescence (CPL) nature glum value +2.2 × 10–3, ligand-to-sulfur interaction size effect. Additionally, Sdots find application as UV-active gel ink anticounterfeiting measures. This demonstrates physical insights into structure optical properties develops CPL-based photonic applications.

Language: Английский

Citations

3
Multicolor circularly polarized luminescence from chiral carbon dots and cellulose nanocrystals assemblies for visual polarization detection DOI

Wenyan Ma,

Di Lu, Junxue Liu

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 495, P. 153453 - 153453

Published: June 24, 2024

Language: Английский

Citations

3
Fluorescence and Circular Dichroism Dual-Mode Probe for Chiral Recognition of Tyrosine and Its Applications in Bioimaging DOI
Foroozan Feizi, Mojtaba Shamsipur,

Mohamad-Bagher Gholivand

et al.

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(36), P. 48058 - 48072

Published: Sept. 2, 2024

Chiral amino acids (AAs) are essential in metabolism and understanding physiological processes, they could be used as biomarkers for the diagnosis of different diseases. In this study, chiral Cdots@Van were prepared by postmodifying an achiral Cdots core with vancomycin recognizing determining enantiomeric excess (ee) tyrosine (Tyr) enantiomers. The fluorescence response is based on "on–off" strategy, quenching percentages d- l-tyrosine. Interestingly, circular dichroism (CD) spectrum responded to only one form Tyr enantiomer, specifically d-Tyr, remained nearly unchanged upon addition l-Tyr. Quantum mechanical (QM) calculations excellent agreement experimental results, confirming stronger binding affinity d-Tyr compared We further investigated recognition ability interconnected particles, which was synthesized using EDC/NHS coupling reaction between molecules without a core. Surprisingly, unlike free molecules, displayed CD spectroscopy, similar what observed Cdots@Van. Crucially, probe has been successfully utilized cell imaging applications.

Language: Английский

Citations

3