Dalton Transactions, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
(Eu 3+ 4 [PTC] 4– 3 ) 0.78 [TREN-1,2-HOPO] 3− 0.22 nanoparticles show a shift of the emission colour from red to green triggered by carbonate, allowing luminescence-driven qualitative and quantitative determination carbonate content in water.
Language: Английский
ACS Applied Materials & Interfaces, Journal Year: 2023, Volume and Issue: 15(2), P. 2499 - 2528
Published: Jan. 5, 2023
Lanthanide-doped upconversion nanoparticles (UCNPs) possess the remarkable ability to convert multiple near-infrared (NIR) photons into higher energy ultraviolet-visible (UV-vis) photons, making them a prime candidate for several advanced applications within realm of nanotechnology. Compared traditional organic fluorophores and quantum dots (QDs), UCNPs narrower emission bands (fwhm 10-50 nm), large anti-Stokes shifts, low toxicity, high chemical stability, resistance photobleaching blinking. In addition, unlike UV-vis excitation, NIR excitation is nondestructive at lower power intensities has tissue penetration depths (up 2 mm) with autofluorescence scattering. Together, these properties make exceedingly favored bioanalytical theranostic applications, where systems have been well-explored. are also well-suited bioimaging, optically modulating chemistries, forensic science, other state-of-the-art research applications. this review, an up-to-date account emerging in UCNP research, beyond theranostics, presented including optogenetics, super-resolution imaging, encoded barcodes, fingerprinting, vision, UCNP-assisted photochemical manipulations, optical tweezers, 3D printing, lasing, NIR-II UCNP-molecule nanohybrids, UCNP-based persistent luminescent nanocrystals.
Language: Английский
Citations
80
Nano Today, Journal Year: 2022, Volume and Issue: 43, P. 101439 - 101439
Published: March 3, 2022
Language: Английский
Citations
74
ACS Applied Bio Materials, Journal Year: 2020, Volume and Issue: 4(5), P. 3937 - 3961
Published: Dec. 14, 2020
Bacterial infection is a universal threat to public health, which not only causes many serious diseases but also exacerbates the condition of patients cancer, pandemic diseases, e.g., COVID-19, and so on. Antibiotic therapy has been used be an effective way for common bacterial disinfection. However, due misuse abuse antibiotics, more antibiotic-resistant bacteria have emerged as fatal threats human beings. At present, than 700,000 die every year with infections because lack treatment. It frustrating that pace development antibiotics lags far behind resistance, estimation 10 million deaths per from after 2050. Facing such rigorous challenge, approaches disinfection are urgently demanded. The recently developed near-infrared (NIR) light-irradiation-based highly promising shatter resistance by employing NIR light-responsive materials mediums generate antibacterial factors heat, reactive oxygen species (ROS), This treatment approach proved potent candidate accurately realize spatiotemporal control, while effectively eradicating multidrug-resistant inhibiting antibiotic resistance. Herein, we summarize latest progress light-based Ultimately, current challenges perspectives in this field discussed.
Language: Английский
Citations
84
Chemical Engineering Journal, Journal Year: 2022, Volume and Issue: 452, P. 139649 - 139649
Published: Oct. 8, 2022
Language: Английский
Citations
67
Biomedicines, Journal Year: 2021, Volume and Issue: 9(7), P. 756 - 756
Published: June 29, 2021
Due to the unique properties of lanthanide-doped upconverting nanoparticles (UCNP) under near-infrared (NIR) light, last decade has shown a sharp progress in their biomedicine applications. Advances techniques for polymer, dye, and bio-molecule conjugation on surface further expanded dynamic opportunities optogenetics, oncotherapy bioimaging. In this account, considering primary benefits such as absence photobleaching, photoblinking, autofluorescence UCNPs not only facilitate construction accurate, sensitive multifunctional nanoprobes, but also improve therapeutic diagnostic results. We introduce, with basic knowledge upconversion, mechanisms involved photon upconversion discuss how can be implemented biological practices. focused review, we categorize applications UCNP-based various strategies into following domains: neuromodulation, immunotherapy, drug delivery, photodynamic photothermal therapy, bioimaging biosensing. Herein, current emerging bioapplications cutting edge nano-/biointerfacing UCNPs. Finally, review provides concluding remarks future challenges clinical translation UCNPs-based nanotechnology research.
Language: Английский
Citations
63
Advanced Functional Materials, Journal Year: 2022, Volume and Issue: 32(37)
Published: May 1, 2022
Abstract Despite the significant advancements of developing upconversion nanoparticles (UCNPs) for high performance biosensing and bioimaging, development DNA‐functionalized UCNPs with thin coatings, efficient surface passivation, fully functional DNAs hybridization sensing in biological media remains extremely challenging. Here, a straightforward concept labeling DNA to polysulfonate polymer layer on is presented. Both preserve their full functionality as demonstrated by Förster resonance energy transfer (FRET) assays Cy3‐conjugated complementary DNA. The important bioanalytical benefits UCNP‐DNA nanohybrids are implementation into rapid wash‐free microRNA FRET assays. Using simple fiber‐coupled USB‐spectrometer 980 nm diode laser excitation 96‐well microplate, ratiometric from UCNP‐to‐Cy3 can quantify miR20a 0.01–10 × 10 −9 m concentration range detection limit 30 −12 (4.5 fmol miR20a), which more than 20‐fold lower compared quantum dot‐based thin‐coating DNA‐UCNP have strong potential translating advanced DNA‐based biosensing, high‐throughput point‐of‐care clinical diagnostics.
Language: Английский
Citations
61
Biomaterials, Journal Year: 2022, Volume and Issue: 286, P. 121577 - 121577
Published: May 19, 2022
Language: Английский
Citations
57
Advanced Drug Delivery Reviews, Journal Year: 2022, Volume and Issue: 188, P. 114414 - 114414
Published: July 7, 2022
Language: Английский
Citations
48
Advanced Functional Materials, Journal Year: 2023, Volume and Issue: 33(18)
Published: Feb. 20, 2023
Abstract Orthogonal upconversion with color‐switchable emissions under different excitation conditions provides new chances to diverse frontier applications of luminescent materials. However, the previous orthogonal systems compulsorily require precise control spatial distributions dopants and host compositions avoid spectral cross‐talk, greatly limiting their synthesis application. Herein, a conceptual design is presented realize by selectively activating sensitizers activators in nanostructure. In detail, 915 nm laser, instead mostly used 980 nm, adopted activate sensitizer Yb 3+ because broad 2 F 5/2 ← 7/2 absorption band; while it non‐responsive Er , consequently avoiding cross‐talk due simultaneous activation both irradiation as shown works. Such selective strategy able red/green, blue/red, blue/green single nanoparticle simply altering wavelength from 1530 nm. More interestingly, further allows for full‐color output temporal dynamics. The findings suggest facile but effective approach smart materials, showing great potential multi‐level anti‐counterfeiting, information security biological applications.
Language: Английский
Citations
34
Advanced Materials, Journal Year: 2023, Volume and Issue: 35(42)
Published: Sept. 19, 2023
Abstract Optogenetic modulation of brain neural activity that combines optical and electrical modes in a unitary system has recently gained robust momentum. Controlling illumination spatial coverage, designing light‐activated modulators, developing wireless light delivery data transmission are crucial for maximizing the use neuromodulation. To this end, biocompatible electrodes with enhanced optoelectrical performance, device integration multiplexed addressing, transmission, multimodal operation soft systems have been developed. This review provides an outlook uniformly illuminating large areas while spatiotemporally imaging responses upon stimulation little artifacts. Representative concepts important breakthroughs, such as head‐mounted illumination, multiple implanted fibers, micro‐light‐delivery devices, discussed. Examples techniques incorporate electrophysiological monitoring presented. Challenges perspectives posed further research efforts toward high‐density interface modulation, potential nonpharmacological neurological disease treatments stimulation.
Language: Английский
Citations
28