Nanoarchitecture-Integrated Hydrogel Systems toward Therapeutic Applications

ACS Nano, Journal Year: 2023, Volume and Issue: 17(9), P. 7953 - 7978

Published: April 18, 2023

Hydrogels, as one of the most feasible soft biomaterials, have gained considerable attention in therapeutic applications by virtue their tunable properties including superior patient compliance, good biocompatibility and biodegradation, high cargo-loading efficiency. However, hydrogel application is still limited some challenges like inefficient encapsulation, easy leakage loaded cargoes, lack controllability. Recently, nanoarchitecture-integrated systems were found to be therapeutics with optimized properties, extending bioapplication. In this review, we briefly presented category hydrogels according synthetic materials further discussed advantages Additionally, various nanoarchitecture hybrid biomedical engineering are systematically summarized, cancer therapy, wound healing, cardiac repair, bone regeneration, diabetes obesity therapy. Last, current challenges, limitations, future perspectives development flexible addressed.

Language: Английский

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Biocompatible 2D Materials via Liquid Phase Exfoliation

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(24)

Published: March 8, 2024

Abstract 2D materials (2DMs), such as graphene, transition metal dichalcogenides (TMDs), and black phosphorus (BP), have been proposed for different types of bioapplications, owing to their unique physicochemical, electrical, optical, mechanical properties. Liquid phase exfoliation (LPE), one the most effective up‐scalable size‐controllable methods, is becoming standard process produce high quantities various 2DM it can benefit from use green biocompatible conditions. The resulting exfoliated layered garnered significant attention because biocompatibility potential in biomedicine new multimodal therapeutics, antimicrobials, biosensors. This review focuses on production LPE‐assisted 2DMs aqueous solutions with or without aid surfactants, bioactive, non‐natural molecules, providing insights into possibilities applications biological biomedical fields.

Language: Английский

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An insight into the dual role of MoS2-based nanocarriers in anticancer drug delivery and therapy

Acta Biomaterialia, Journal Year: 2024, Volume and Issue: 179, P. 36 - 60

Published: March 27, 2024

Language: Английский

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Recent Advances in Two-Dimensional Nanomaterials for Healthcare Monitoring

ACS Sensors, Journal Year: 2024, Volume and Issue: 9(4), P. 1706 - 1734

Published: April 2, 2024

The development of advanced technologies for the fabrication functional nanomaterials, nanostructures, and devices has facilitated biosensors analyses. Two-dimensional (2D) with unique hierarchical structures, a high surface area, ability to be functionalized target detection at surface, exhibit potential biosensing applications. electronic properties, mechanical flexibility, optical, electrochemical, physical properties 2D nanomaterials can easily modulated, enabling construction platforms various analytes targeted recognition, sensitivity, selectivity. This review provides an overview recent advances in nanostructures used biosensor wearable-sensor healthcare health-monitoring Finally, advantages 2D-nanomaterial-based several challenges their optimal operation have been discussed facilitate smart high-performance future.

Language: Английский

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MXenes in healthcare: synthesis, fundamentals and applications

Chemical Society Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Since their discovery over a decade ago, MXenes have transformed the field of "materials for healthcare", stimulating growing interest in healthcare-related applications. These developments also driven significant advancements MXenes' synthesis. This review systematically examines synthesis and applications sensing biomedical fields, underscoring pivotal role addressing critical challenges modern healthcare. We describe experimental by combining appropriate laboratory modules with mechanistic principles underlying each step. In addition, we provide extensive details on parameters, considerations, essential instructions successful Various healthcare including sensing, imaging, synergistic therapies, regenerative medicine, wearable devices been explored. further highlight emerging trends MXenes, viz., as nanovehicles drug delivery, vectors gene therapy, tools immune profiling. By identifying important parameters that define utility applications, this outlines strategies to regulate profile, thereby serving valuable guide design application-specific properties. The final section integrates research theoretical studies comprehensive understanding field. It technologies, such artificial intelligence (AI) machine learning (ML), accelerating material discovery, structure-property optimization, automation. Complemented detailed supplementary information synthesis, stability, biocompatibility, environmental impact, insights, offers profound knowledge base diverse family 2D materials. Finally, compared potential other materials underscore existing prioritize interdisciplinary collaboration. synthesizing key from its current (especially 2018 onward), provides cohesive assessment MXene foundations prospects sector.

Language: Английский

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Advances in Single-component inorganic nanostructures for photoacoustic imaging guided photothermal therapy

Advanced Drug Delivery Reviews, Journal Year: 2022, Volume and Issue: 192, P. 114644 - 114644

Published: Dec. 6, 2022

Language: Английский

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Properties and applications of quantum dots derived from two-dimensional materials

Advances in Physics X, Journal Year: 2022, Volume and Issue: 7(1)

Published: April 17, 2022

Quantum dots based on two-dimensional materials (2D-QDs) have received significant attention due to their exceptional physical, chemical, and biological properties. They shown unprecedented performance efficiency in many fields including electronics, spintronics, energy, water treatment, sensors, applications. This article provides a critical review the recent progress of 2D-DQs, synthesis approaches, categories, properties, The introduces various types 2D-QDs, such as graphene, hBN, silicene, phosphorene, transition metal dichalcogenides, MXenes that show wide range properties applicable for different fields. We describe detail electronic, magnetic, optical, catalytic, 2D-QDs relate them suitable Future directions research are given novel provided by newly discovered 2D heterostructures.

Language: Английский

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Recent Development of Polydopamine Anti-Bacterial Nanomaterials

International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(13), P. 7278 - 7278

Published: June 30, 2022

Polydopamine (PDA), as a mussel-inspired material, exhibits numerous favorable performance characteristics, such simple preparation process, prominent photothermal transfer efficiency, excellent biocompatibility, outstanding drug binding ability, and strong adhesive properties, showing great potential in the biomedical field. The rapid development of this field past few years has engendered substantial progress PDA antibacterial materials. This review presents recent advances PDA-based antimicrobial materials, including methods mechanisms free-standing materials composite Furthermore, urgent challenges future research opportunities for are discussed.

Language: Английский

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Flexible polymeric patch based nanotherapeutics against non-cancer therapy

Bioactive Materials, Journal Year: 2022, Volume and Issue: 18, P. 471 - 491

Published: March 29, 2022

Language: Английский

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A comprehensive review of synthesis, structure, properties, and functionalization of MoS2; emphasis on drug delivery, photothermal therapy, and tissue engineering applications

Journal of Drug Delivery Science and Technology, Journal Year: 2022, Volume and Issue: 76, P. 103767 - 103767

Published: Sept. 3, 2022

Language: Английский

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