Cited by Antibacterial functionalized carbon dots and their application in bacterial infections and inflammation

Unraveling the Structure Transition and Peroxidase Mimic Activity of Copper Sites over Atomically Dispersed Copper‐Doped Carbonized Polymer Dots DOI

Fucheng Gao, Jian Huang,

Ying Ruan

et al.

Angewandte Chemie International Edition, Journal Year: 2022, Volume and Issue: 62(7)

Published: Dec. 24, 2022

The lack of systematic structural resolution makes it difficult to build specific transition-metal-atom-doped carbonized polymer dots (TMA-doped CPDs). Herein, the structure-activity relationship between Cu atoms and CPDs was evaluated by studying peroxidase-like properties Glu-Cu-CPDs prepared using copper glutamate (Glu) with a Cu-N2 O2 initial structure. results showed that bound in form C2 , indicating Cu-O bonds changed into Cu-C under hydrothermal conditions. This phenomenon also observed other copper-doped CPDs. Moreover, carboxyl amino groups content decreased after copper-atom doping. Theoretical calculations revealed dual-site catalytic mechanism for catalyzing H2 . detection intracellular suggested their application prospects. Our study provides an in-depth understanding formation TMA-doped-CPDs, allowing generation TMA-doped-CPDs.

Language: Английский

Citations

Recent advances on nanomaterials for antibacterial treatment of oral diseases DOI

Zetong Chen,

Zhaoyou Chu,

Yechun Jiang

et al.

Materials Today Bio, Journal Year: 2023, Volume and Issue: 20, P. 100635 - 100635

Published: April 15, 2023

An imbalance of bacteria in oral environment can lead to a variety diseases, such as periodontal disease, dental caries, and peri-implant inflammation. In the long term, view increasing bacterial resistance, finding suitable alternatives traditional antibacterial methods is an important research today. With development nanotechnology, agents based on nanomaterials have attracted much attention field due their low cost, stable structures, excellent properties broad spectrum. Multifunctional break through limitations single therapy functions remineralization osteogenesis basis antibacterial, which has made significant progress long-term prevention treatment diseases. this review, we summarized applications metal oxides, organic composite recent five years. These not only inactivate bacteria, but also achieve more efficient diseases by improving materials themselves, enhancing precision targeted delivery drugs imparting richer functions. Finally, future challenges untapped potential are elaborated demonstrate prospects field.

Language: Английский

Citations

A Multifunctional Nanozyme with NADH Dehydrogenase‐Like Activity and Nitric Oxide Release under Near‐Infrared Light Irradiation as an Efficient Therapeutic for Antimicrobial Resistance Infection and Wound Healing DOI

Yi Wang,

Hongdong Shi,

Hailin Zhang

et al.

Advanced Healthcare Materials, Journal Year: 2023, Volume and Issue: 12(25)

Published: June 16, 2023

In recent years, antimicrobial resistance (AMR) has become one of the greatest threats to human health. There is an urgent need develop new antibacterial agents effectively treat AMR infection. Herein, a novel nanozyme platform (Cu,N-GQDs@Ru-NO) prepared, where Cu,N-doped graphene quantum dots (Cu,N-GQDs) are covalently functionalized with nitric oxide (NO) donor, ruthenium nitrosyl (Ru-NO). Under 808 nm near-infrared (NIR) light irradiation, Cu,N-GQDs@Ru-NO demonstrates nicotinamide adenine dinucleotide (NADH) dehydrogenase-like activity for photo-oxidizing NADH NAD+ , thus disrupting redox balance in bacterial cells and resulting death; meanwhile, onsite NIR light-delivered NO eradicates methicillin-resistant Staphylococcus aureus (MRSA) biofilms, promotes wound healing; furthermore, shows excellent photothermal effect that enhances efficacy as well. With combination dehydrogenase activity, therapy, gas displays both vitro vivo MRSA infection biofilm eradication, which provides therapeutic modality treating inflammatory wounds.

Language: Английский

Citations

Rational Designs of Biomaterials for Combating Oral Biofilm Infections DOI

Zhengrong Yin,

Yaxi Liu,

Annikaer Anniwaer

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 11, 2023

Oral biofilms, which are also known as dental plaque, the culprit of a wide range oral diseases and systemic diseases, thus contributing to serious health risks. The manner how achieve good control biofilms has been an increasing public concern. Novel antimicrobial biomaterials with highly controllable fabrication functionalization have proven be promising candidates. However, previous reviews generally emphasized physicochemical properties, action mode, application effectiveness those biomaterials, whereas insufficient attention given design rationales tailored different infection types scenarios. To offer guidance for better diversification anti-oral-biofilm this review details up-to-date in three aspects: core strategies combating biofilm, well advanced antibiofilm capacity multiple functions based on improvement or combination abovementioned strategies. Thereafter, insights existing challenges future biomaterial-assisted biofilm treatments proposed, hoping provide theoretical basis reference subsequent biomaterials.

Language: Английский

Citations

Antibacterial functionalized carbon dots and their application in bacterial infections and inflammation DOI

Meng Fang, Liping Lin,

Muyue Zheng

et al.

Journal of Materials Chemistry B, Journal Year: 2023, Volume and Issue: 11(39), P. 9386 - 9403

Published: Jan. 1, 2023

Antimicrobial mechanisms of functionalized carbon dots: covalent and non-covalent interactions, reactive oxygen species, photothermal effect, size effect ( E. coli was used as a model).

Language: Английский

Citations