Stimuli-activatable nanomedicine meets cancer theranostics

Theranostics, Journal Year: 2023, Volume and Issue: 13(15), P. 5386 - 5417

Published: Jan. 1, 2023

Stimuli-activatable strategies prevail in the design of nanomedicine for cancer theranostics.Upon exposure to endogenous/exogenous stimuli, stimuli-activatable could be self-assembled, disassembled, or functionally activated improve its biosafety and diagnostic/therapeutic potency.A myriad tumor-specific features, including a low pH, high redox level, overexpressed enzymes, along with exogenous physical stimulation sources (light, ultrasound, magnet, radiation) have been considered nano-medicinal products.Recently, novel stimuli explored elegant designs emerged nanomedicine.In addition, multi-functional theranostic has employed imaging-guided image-assisted antitumor therapy.In this review, we rationalize development clinical pressing needs.Stimuli-activatable self-assembly, disassembly functional activation approaches developing realize better efficacy are elaborated state-of-the-art advances their structural detailed.A reflection, status, future perspectives provided.

Language: Английский

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Iron-based metal–organic frameworks and their derived materials for photocatalytic and photoelectrocatalytic reactions

Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 499, P. 215538 - 215538

Published: Nov. 1, 2023

Language: Английский

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Plant exosome nanovesicles (PENs): green delivery platforms

Materials Horizons, Journal Year: 2023, Volume and Issue: 10(10), P. 3879 - 3894

Published: Jan. 1, 2023

Structure of plant-derived vesicles and their bioactive applications. Created with BioRender.com

Language: Английский

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ROS Balance Autoregulating Core–Shell CeO2@ZIF-8/Au Nanoplatform for Wound Repair

Nano-Micro Letters, Journal Year: 2024, Volume and Issue: 16(1)

Published: March 21, 2024

Reactive oxygen species (ROS) plays important roles in living organisms. While ROS is a double-edged sword, which can eliminate drug-resistant bacteria, but excessive levels cause oxidative damage to cells. A core-shell nanozyme, CeO

Language: Английский

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Metal‐Organic Frameworks (MOFs): Classification, Synthesis, Modification, and Biomedical Applications

Small, Journal Year: 2024, Volume and Issue: 20(47)

Published: Aug. 16, 2024

Abstract Metal‐organic frameworks (MOFs) are a new variety of solid crystalline porous functional materials. As an extension inorganic materials, it has made important progress in preparation and application. MOFs widely used various fields such as gas adsorption storage, drug delivery, sensing, biological imaging due to their high specific surface area, porosity, adjustable pore size, abundant active sites, modification by introducing groups. In this paper, the types classified, synthesis methods mechanisms materials summarized. Finally, application prospects challenges metal‐organic framework biomedical field discussed, hoping promote multidisciplinary fields.

Language: Английский

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Hyperuricemia research progress in model construction and traditional Chinese medicine interventions

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: March 7, 2024

Hyperuricemia (HUA), a severe metabolic disease derived from purine metabolism disorder, will lead to abnormally increased serum uric acid (SUA) levels in the body. Studies have shown that HUA is highly related gout, hypertension, diabetes, coronary heart disease, chronic kidney diseases, and so on. Traditional Chinese medicine (TCM) shows excellent results treating because of its unique advantages multi-metabolites multi-targets. This article reports on use TCM components for (UA)-lowering activity with efficacy low side effects based established models. work summarizes limitations various models evaluation. Applications treatment also been discussed detail. paper reveals recent research progress constructing evaluation systematic interventions. It provide scientific reference establishing model suggest future TCM-related studies.

Language: Английский

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Photo-responsive polydopamine nanoenzyme microneedles with oxidative stress regulation ability for atopic dermatitis treatment

Nano Today, Journal Year: 2024, Volume and Issue: 56, P. 102241 - 102241

Published: March 28, 2024

Language: Английский

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Metal-organic frameworks for biomedical applications: A review

Advances in Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 331, P. 103210 - 103210

Published: June 5, 2024

Language: Английский

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Artificial Intelligence-Powered Materials Science

Nano-Micro Letters, Journal Year: 2025, Volume and Issue: 17(1)

Published: Feb. 6, 2025

Abstract The advancement of materials has played a pivotal role in the human civilization, and emergence artificial intelligence (AI)-empowered science heralds new era with substantial potential to tackle escalating challenges related energy, environment, biomedical concerns sustainable manner. exploration development are poised assume critical attaining technologically advanced solutions that environmentally friendly, energy-efficient, conducive well-being. This review provides comprehensive overview current scholarly progress intelligence-powered its cutting-edge applications. We anticipate AI technology will be extensively utilized material research development, thereby expediting growth implementation novel materials. serve as catalyst for innovation, turn, advancements innovation further enhance capabilities AI-powered science. Through synergistic collaboration between science, we stand realize future propelled by

Language: Английский

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Tunable metal–organic frameworks assist in catalyzing DNAzymes with amplification platforms for biomedical applications

Chemical Society Reviews, Journal Year: 2023, Volume and Issue: 52(21), P. 7549 - 7578

Published: Jan. 1, 2023

Various binding modes of tunable metal organic frameworks (MOFs) and functional DNAzymes (Dzs) synergistically catalyze the emergence abundant nanoplatforms.

Language: Английский

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